Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Tubulin alpha chain

Gene

GGTG_10309

Organism
Gaeumannomyces graminis var. tritici (strain R3-111a-1) (Wheat and barley take-all root rot fungus)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandGTP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Tubulin alpha chainUniRule annotation
Gene namesi
ORF Names:GGTG_10309Imported
OrganismiGaeumannomyces graminis var. tritici (strain R3-111a-1) (Wheat and barley take-all root rot fungus)
Taxonomic identifieri644352 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesSordariomycetidaeMagnaporthalesMagnaporthaceaeGaeumannomyces
Proteomesi
  • UP000006039 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, CytoskeletonSAAS annotation, MicrotubuleUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi29850.GGTG_10309T0.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini50 – 247TubulinInterPro annotationAdd BLAST198
Domaini249 – 399Tubulin_CInterPro annotationAdd BLAST151

Sequence similaritiesi

Belongs to the tubulin family.UniRule annotationSAAS annotation

Phylogenomic databases

OrthoDBiEOG092C2JRV.

Family and domain databases

Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
InterProiView protein in InterPro
IPR002452. Alpha_tubulin.
IPR008280. Tub_FtsZ_C.
IPR000217. Tubulin.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR037103. Tubulin/FtsZ_C_sf.
IPR036525. Tubulin/FtsZ_GTPase_sf.
IPR017975. Tubulin_CS.
IPR003008. Tubulin_FtsZ_GTPase.
PANTHERiPTHR11588. PTHR11588. 1 hit.
PfamiView protein in Pfam
PF00091. Tubulin. 1 hit.
PF03953. Tubulin_C. 1 hit.
PRINTSiPR01162. ALPHATUBULIN.
PR01161. TUBULIN.
SMARTiView protein in SMART
SM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
PROSITEiView protein in PROSITE
PS00227. TUBULIN. 1 hit.

Sequencei

Sequence statusi: Complete.

J3P9Y5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKGEVLHLHL GQAGTQLGNS AWELYLLEHG LGHDGKPDPN AKDIAEGGSF
60 70 80 90 100
ETFFTETSGG KYVPRSLFVD LDPSPIDEIR TGGYRQLFHP ELLISGKEDA
110 120 130 140 150
ANNYARGHYT IGKEMVDNVI ERIRRVADNC NSLQGFLIFH SFGGGTGSGF
160 170 180 190 200
GALLLERLST EYGKKSKLEF AVYPAPRVST AVVEPYNAVL STHSTIENSD
210 220 230 240 250
CTFLVDNEAV YDICRRNLDI PRPSYEHLNR LIAQVVSSIT SSLRFDGALN
260 270 280 290 300
VDLNEFQTNL VPYPRIHYPL ISYAPVISAT KSAHESFKVH DLTFQCFEPN
310 320 330 340 350
NQMVVCDPRN GKYMAVALLY RGDVVPRDCN AAVAALKAKA SFNLVEWCPT
360 370 380 390 400
GFKIGINYQK PVAVPSATPA DGALASVDRS VSMLSNTTAI AEAWSRLDHK
410 420 430 440 450
FDLMYSKRAF VHWYVGEGME EGEFSEARED LAALEKDYEE VAADSSFEPE

EGEAEY
Length:456
Mass (Da):50,419
Last modified:October 3, 2012 - v1
Checksum:i401DAEBB4FB83A47
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ADBI01000839 Genomic DNA. No translation available.
GL385399 Genomic DNA. Translation: EJT73471.1.
RefSeqiXP_009226445.1. XM_009228181.1.

Genome annotation databases

EnsemblFungiiGGTG_10309T0; GGTG_10309T0; GGTG_10309.
GeneIDi20350767.

Similar proteinsi

Entry informationi

Entry nameiJ3P9Y5_GAGT3
AccessioniPrimary (citable) accession number: J3P9Y5
Entry historyiIntegrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: November 22, 2017
This is version 45 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported