Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Tribbles homolog 3

Gene

TRIB3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Tribbles homolog 3Imported
Gene namesi
Name:TRIB3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 20

Organism-specific databases

EuPathDBiHostDB:ENSG00000101255.10.
HGNCiHGNC:16228. TRIB3.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000101255.

PTM / Processingi

Proteomic databases

MaxQBiJ3KR25.
PaxDbiJ3KR25.
PRIDEiJ3KR25.

Expressioni

Gene expression databases

BgeeiENSG00000101255.
ExpressionAtlasiJ3KR25. baseline and differential.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliJ3KR25.
SMRiJ3KR25.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini95 – 342Protein kinaseInterPro annotationAdd BLAST248

Phylogenomic databases

eggNOGiKOG0583. Eukaryota.
COG0515. LUCA.
GeneTreeiENSGT00880000137914.
OMAiYTCKVYP.
OrthoDBiEOG091G07JM.
PhylomeDBiJ3KR25.

Family and domain databases

InterProiView protein in InterPro
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR024104. Tribbles/Ser_Thr_kinase_40.
IPR024106. Tribbles_TRB3.
PANTHERiPTHR22961. PTHR22961. 1 hit.
PTHR22961:SF21. PTHR22961:SF21. 1 hit.
PfamiView protein in Pfam
PF00069. Pkinase. 1 hit.
SMARTiView protein in SMART
SM00220. S_TKc. 1 hit.
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiView protein in PROSITE
PS50011. PROTEIN_KINASE_DOM. 1 hit.

Sequencei

Sequence statusi: Complete.

J3KR25-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVLMHLAVKN NRMSANNDHF LTPTWQQMRA TPLAAPAGSL SRKKRLELDD
60 70 80 90 100
NLDTERPVQK RARSGPQPRL PPCLLPLSPP TAPDRATAVA TASRLGPYVL
110 120 130 140 150
LEPEEGGRAY QALHCPTGTE YTCKVYPVQE ALAVLEPYAR LPPHKHVARP
160 170 180 190 200
TEVLAGTQLL YAFFTRTHGD MHSLVRSRHR IPEPEAAVLF RQMATALAHC
210 220 230 240 250
HQHGLVLRDL KLCRFVFADR ERKKLVLENL EDSCVLTGPD DSLWDKHACP
260 270 280 290 300
AYVGPEILSS RASYSGKAAD VWSLGVALFT MLAGHYPFQD SEPVLLFGKI
310 320 330 340 350
RRGAYALPAG LSAPARCLVR CLLRREPAER LTATGILLHP WLRQDPMPLA
360 370 380
PTRSHLWEAA QVVPDGLGLD EAREEEGDRE VVLYG
Length:385
Mass (Da):42,757
Last modified:October 3, 2012 - v1
Checksum:i46A0C1B6EB5E814C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL034548 Genomic DNA. No translation available.
KF456775 Genomic DNA. No translation available.
RefSeqiNP_001288130.1. NM_001301201.1.
XP_016883478.1. XM_017027989.1.
UniGeneiHs.516826.

Genome annotation databases

EnsembliENST00000422053; ENSP00000415416; ENSG00000101255.
GeneIDi57761.
UCSCiuc002wdn.4. human.

Similar proteinsi

Entry informationi

Entry nameiJ3KR25_HUMAN
AccessioniPrimary (citable) accession number: J3KR25
Entry historyiIntegrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: September 27, 2017
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported