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Protein
Submitted name:

Peptidyl-tRNA hydrolase 2, mitochondrial

Gene

PTRH2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Peptidyl-tRNA hydrolase 2, mitochondrialImported
Gene namesi
Name:PTRH2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

HGNCiHGNC:24265. PTRH2.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei20 – 3819HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

EPDiJ3KQ48.
PaxDbiJ3KQ48.
PRIDEiJ3KQ48.

Expressioni

Gene expression databases

ExpressionAtlasiJ3KQ48. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000376758.

Structurei

3D structure databases

ProteinModelPortaliJ3KQ48.
SMRiJ3KQ48. Positions 64-180.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3282. Eukaryota.
COG1990. LUCA.
GeneTreeiENSGT00390000015991.
KOiK04794.
OMAiQVAHGAV.
PhylomeDBiJ3KQ48.

Family and domain databases

Gene3Di3.40.1490.10. 1 hit.
InterProiIPR023476. Pep_tRNA_hydro_II_dom.
IPR002833. PTH2.
[Graphical view]
PfamiPF01981. PTH2. 1 hit.
[Graphical view]
SUPFAMiSSF102462. SSF102462. 1 hit.
TIGRFAMsiTIGR00283. arch_pth2. 1 hit.

Sequencei

Sequence statusi: Complete.

J3KQ48-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMPSKSLVME YLAHPSTLGL AVGVACGMCL GWSLRVCFGM LPKSKTSKTH
60 70 80 90 100
TDTESEASIL GDSGEYKMIL VVRNDLKMGK GKVAAQCSHA AVSAYKQIQR
110 120 130 140 150
RNPEMLKQWE YCGQPKVVVK APDEETLIAL LAHAKMLGLT VSLIQDAGRT
160 170 180
QIAPGSQTVL GIGPGPADLI DKVTGHLKLY
Length:180
Mass (Da):19,325
Last modified:October 3, 2012 - v1
Checksum:iFCA0F7AA92E9EC8D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC091271 Genomic DNA. No translation available.
RefSeqiNP_001015509.1. NM_001015509.2.
UniGeneiHs.12677.

Genome annotation databases

EnsembliENST00000409433; ENSP00000387180; ENSG00000141378.
GeneIDi51651.
KEGGihsa:51651.
UCSCiuc060idm.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC091271 Genomic DNA. No translation available.
RefSeqiNP_001015509.1. NM_001015509.2.
UniGeneiHs.12677.

3D structure databases

ProteinModelPortaliJ3KQ48.
SMRiJ3KQ48. Positions 64-180.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000376758.

Proteomic databases

EPDiJ3KQ48.
PaxDbiJ3KQ48.
PRIDEiJ3KQ48.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000409433; ENSP00000387180; ENSG00000141378.
GeneIDi51651.
KEGGihsa:51651.
UCSCiuc060idm.1. human.

Organism-specific databases

CTDi51651.
HGNCiHGNC:24265. PTRH2.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3282. Eukaryota.
COG1990. LUCA.
GeneTreeiENSGT00390000015991.
KOiK04794.
OMAiQVAHGAV.
PhylomeDBiJ3KQ48.

Miscellaneous databases

ChiTaRSiPTRH2. human.
GenomeRNAii51651.
NextBioi35535268.

Gene expression databases

ExpressionAtlasiJ3KQ48. baseline and differential.

Family and domain databases

Gene3Di3.40.1490.10. 1 hit.
InterProiIPR023476. Pep_tRNA_hydro_II_dom.
IPR002833. PTH2.
[Graphical view]
PfamiPF01981. PTH2. 1 hit.
[Graphical view]
SUPFAMiSSF102462. SSF102462. 1 hit.
TIGRFAMsiTIGR00283. arch_pth2. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
    Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R., Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A., Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J., Chang J.L.
    , Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J., DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D., Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A., Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.
    Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  4. Ensembl
    Submitted (AUG-2012) to UniProtKB
    Cited for: IDENTIFICATION.
  5. "N-terminome analysis of the human mitochondrial proteome."
    Vaca Jacome A.S., Rabilloud T., Schaeffer-Reiss C., Rompais M., Ayoub D., Lane L., Bairoch A., Van Dorsselaer A., Carapito C.
    Proteomics 15:2519-2524(2015) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiJ3KQ48_HUMAN
AccessioniPrimary (citable) accession number: J3KQ48
Entry historyi
Integrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: March 16, 2016
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.