KIF3A

Functionⁱ

Regions

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Nucleotide bindingⁱ	100 – 107	ATPPROSITE-ProRule annotation		8

GO - Molecular functionⁱ

ATP binding Source: UniProtKB-UniRule
microtubule binding Source: InterPro
microtubule motor activity Source: InterPro

Complete GO annotation...

GO - Biological processⁱ

microtubule-based movement Source: InterPro

Complete GO annotation...

Keywordsⁱ

Molecular function	Motor proteinPROSITE-ProRule annotation
Ligand	ATP-bindingPROSITE-ProRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Kinesin-like proteinUniRule annotation
Gene namesⁱ	Name:KIF3AImported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 5

Organism-specific databases

Human Gene Nomenclature Database More...HGNCⁱ	HGNC:6319. KIF3A.

HGNCⁱ

HGNC:6319. KIF3A.

Subcellular locationⁱ

GO - Cellular componentⁱ

microtubule Source: UniProtKB-KW

Complete GO annotation...

Keywords - Cellular componentⁱ

MicrotubuleUniRule annotation

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000131437.

OpenTargetsⁱ

ENSG00000131437.

PTM / Processingⁱ

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	J3KPF9.
PaxDbⁱ	J3KPF9.
PeptideAtlas More...PeptideAtlasⁱ	J3KPF9.
PRIDEⁱ	J3KPF9.

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000131437.
ExpressionAtlasⁱ	J3KPF9. baseline and differential.

Interactionⁱ

GO - Molecular functionⁱ

microtubule binding Source: InterPro

Complete GO annotation...

Protein-protein interaction databases

IntActⁱ	J3KPF9. 7 interactors.

IntActⁱ

J3KPF9. 7 interactors.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	J3KPF9.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	14 – 345	Kinesin motorInterPro annotationAdd BLAST		332

Coiled coil

Feature key	Position(s)	DescriptionActions	Length
Coiled coilⁱ	356 – 380	Sequence analysisAdd BLAST	25
Coiled coilⁱ	426 – 481	Sequence analysisAdd BLAST	56
Coiled coilⁱ	490 – 541	Sequence analysisAdd BLAST	52
Coiled coilⁱ	556 – 587	Sequence analysisAdd BLAST	32

Sequence similaritiesⁱ

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.PROSITE-ProRule annotationSAAS annotation

Keywords - Domainⁱ

Coiled coilSequence analysis

Phylogenomic databases

eggNOGⁱ	KOG4280. Eukaryota. COG5059. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00880000137847.

Family and domain databases

Gene3Dⁱ	3.40.850.10. 1 hit.
InterProⁱ	View protein in InterPro IPR019821. Kinesin_motor_CS. IPR001752. Kinesin_motor_dom. IPR027417. P-loop_NTPase.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00225. Kinesin. 1 hit.
PRINTSⁱ	PR00380. KINESINHEAVY.
SMARTⁱ	View protein in SMART SM00129. KISc. 1 hit.
SUPFAMⁱ	SSF52540. SSF52540. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00411. KINESIN_MOTOR_1. 1 hit. PS50067. KINESIN_MOTOR_2. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

J3KPF9-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MPINKSEKPE SCDNVKVVVR CRPLNEREKS MCYKQAVSVD EMRGTITVHK 
        60         70         80         90        100
TDSSNEPPKT FTFDTVFGPE SKQLDVYNLT ARPIIDSVLE GYNGTIFAYG 
       110        120        130        140        150
QTGTGKTFTM EGVRAIPELR GIIPNSFAHI FGHIAKAEGD TRFLVRVSYL 
       160        170        180        190        200
EIYNEEVRDL LGKDQTQRLE VKERPDVGVY IKDLSAYVVN NADDMDRIMT 
       210        220        230        240        250
LGHKNRSVGA TNMNEHSSRS HAIFTITIEC SEKGIDGNMH VRMGKLHLVD 
       260        270        280        290        300
LAGSERQAKT GATGQRLKEA TKINLSLSTL GNVISALVDG KSTHVPYRNS 
       310        320        330        340        350
KLTRLLQDSL GGNSKTMMCA NIGPADYNYD ETISTLRYAN RAKNIKNKAR 
       360        370        380        390        400
INEDPKDALL RQFQKEIEEL KKKLEEGEEI SGSDISGSEE DDDEEGEVGE 
       410        420        430        440        450
DGEKRKKRRD QAGKKKVSPD KMIEMQAKID EERKALETKL DMEEEERNKA 
       460        470        480        490        500
RAELEKREKD LLKAQQEHQS LLEKLSALEK KVIVGGVDLL AKAEEQEKLL 
       510        520        530        540        550
EESNMELEER RKRAEQLRRE LEEKEQERLD IEEKYTSLQE EAQGKTKKLK 
       560        570        580        590        600
KVWTMLMAAK SEMADLQQEH QREIEGLLEN IRQLSRELRL QMLIIDNFIP 
       610        620        630        640        650
RDYQEMIENY VHWNEDIGEW QLKCVAYTGN NMRKQTPVPD KKEKDPFEVD 
       660        670        680        690        700
LSHVYLAYTE ESLRQSLMKL ERPRTSKGKA RPKTGRRKRS AKPETVIDSL 

LQ

Length:702

Mass (Da):80,355

Last modified:October 3, 2012 - v1

Checksum:ⁱ28EEEA27FBF1F2A2

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC004039 Genomic DNA. No translation available. AC004237 Genomic DNA. No translation available.
NCBI Reference Sequences More...RefSeqⁱ	NP_001287721.1. NM_001300792.1.
UniGeneⁱ	Hs.43670.

Genome annotation databases

Ensemblⁱ	ENST00000378735; ENSP00000368009; ENSG00000131437.
GeneIDⁱ	11127.
UCSC genome browser More...UCSCⁱ	uc003kxp.4. human.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC004039 Genomic DNA. No translation available. AC004237 Genomic DNA. No translation available.
NCBI Reference Sequences More...RefSeqⁱ	NP_001287721.1. NM_001300792.1.
UniGeneⁱ	Hs.43670.

3D structure databases

ProteinModelPortalⁱ	J3KPF9.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

IntActⁱ	J3KPF9. 7 interactors.

IntActⁱ

J3KPF9. 7 interactors.

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	J3KPF9.
PaxDbⁱ	J3KPF9.
PeptideAtlas More...PeptideAtlasⁱ	J3KPF9.
PRIDEⁱ	J3KPF9.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000378735; ENSP00000368009; ENSG00000131437.
GeneIDⁱ	11127.
UCSC genome browser More...UCSCⁱ	uc003kxp.4. human.

Organism-specific databases

CTDⁱ	11127.
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:6319. KIF3A.
Open Targets More...OpenTargetsⁱ	ENSG00000131437.
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG4280. Eukaryota. COG5059. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00880000137847.

Miscellaneous databases

ChiTaRSⁱ	KIF3A. human.
GenomeRNAiⁱ	11127.

Gene expression databases

Bgeeⁱ	ENSG00000131437.
ExpressionAtlasⁱ	J3KPF9. baseline and differential.

Family and domain databases

Gene3Dⁱ	3.40.850.10. 1 hit.
InterProⁱ	View protein in InterPro IPR019821. Kinesin_motor_CS. IPR001752. Kinesin_motor_dom. IPR027417. P-loop_NTPase.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00225. Kinesin. 1 hit.
PRINTSⁱ	PR00380. KINESINHEAVY.
SMARTⁱ	View protein in SMART SM00129. KISc. 1 hit.
SUPFAMⁱ	SSF52540. SSF52540. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00411. KINESIN_MOTOR_1. 1 hit. PS50067. KINESIN_MOTOR_2. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	J3KPF9_HUMAN
Accessionⁱ	J3KPF9Primary (citable) accession number: J3KPF9
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	October 3, 2012
	Last sequence update:	October 3, 2012
	Last modified:	July 5, 2017
	This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termⁱ

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - J3KPF9 (J3KPF9_HUMAN)

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Kinesin-like protein

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Coiled coil

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Caution

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ