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Protein
Submitted name:

Alpha-parvin

Gene

PARVA

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Alpha-parvinImported
Submitted name:
Parvin, alpha, isoform CRA_cImported
Gene namesi
Name:PARVAImported
ORF Names:hCG_23646Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

HGNCiHGNC:14652. PARVA.

Subcellular locationi

GO - Cellular componenti

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000197702.

PTM / Processingi

Proteomic databases

MaxQBiJ3KNQ4.

Expressioni

Gene expression databases

BgeeiENSG00000197702.
ExpressionAtlasiJ3KNQ4. baseline and differential.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiJ3KNQ4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini135 – 241Actin-bindingInterPro annotationAdd BLAST107
Domaini302 – 409Actin-bindingInterPro annotationAdd BLAST108

Phylogenomic databases

eggNOGiKOG3631. Eukaryota.
ENOG410XQWH. LUCA.
GeneTreeiENSGT00390000009673.
KOiK06275.
OMAiHNVSFSF.
OrthoDBiEOG091G0ULB.
TreeFamiTF314025.

Family and domain databases

Gene3Di1.10.418.10. 2 hits.
InterProiView protein in InterPro
IPR001715. CH-domain.
IPR028433. Parvin.
PANTHERiPTHR12114. PTHR12114. 1 hit.
PfamiView protein in Pfam
PF00307. CH. 2 hits.
PIRSFiPIRSF039131. Parvin. 1 hit.
SMARTiView protein in SMART
SM00033. CH. 2 hits.
SUPFAMiSSF47576. SSF47576. 2 hits.
PROSITEiView protein in PROSITE
PS50021. CH. 2 hits.

Sequencei

Sequence statusi: Complete.

J3KNQ4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLGIIPLPFG KPQPQSRRRP LRPPSASSAS RPARGSLRRA MATSPQKSPS
60 70 80 90 100
VPKSPTPKSP PSRKKDDSFL GKLGGTLARR KKAKEVSELQ EEGMNAINLP
110 120 130 140 150
LSPIPFELDP EDTMLEENEV RTMVDPNSRS DPKLQELMKV LIDWINDVLV
160 170 180 190 200
GERIIVKDLA EDLYDGQVLQ KLFEKLESEK LNVAEVTQSE IAQKQKLQTV
210 220 230 240 250
LEKINETLKL PPRSIKWNVD SVHAKSLVAI LHLLVALSQY FRAPIRLPDH
260 270 280 290 300
VSIQVVVVQK REGILQSRQI QEEITGNTEA LSGRHERDAF DTLFDHAPDK
310 320 330 340 350
LNVVKKTLIT FVNKHLNKLN LEVTELETQF ADGVYLVLLM GLLEGYFVPL
360 370 380 390 400
HSFFLTPDSF EQKVLNVSFA FELMQDGGLE KPKPRPEDIV NCDLKSTLRV
410
LYNLFTKYRN VE
Length:412
Mass (Da):46,590
Last modified:October 3, 2012 - v1
Checksum:i74AFBA08C3378167
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009806 Genomic DNA. No translation available.
AC025300 Genomic DNA. No translation available.
CH471064 Genomic DNA. Translation: EAW68525.1.
RefSeqiNP_060692.2. NM_018222.4.
UniGeneiHs.432914.

Genome annotation databases

EnsembliENST00000334956; ENSP00000334008; ENSG00000197702.
GeneIDi55742.
KEGGihsa:55742.
UCSCiuc001mki.5. human.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiJ3KNQ4_HUMAN
AccessioniPrimary (citable) accession number: J3KNQ4
Entry historyiIntegrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: July 5, 2017
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported