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Protein
Submitted name:

Semaphorin-4B

Gene

SEMA4B

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Semaphorin-4BImported
Gene namesi
Name:SEMA4BImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 15

Organism-specific databases

HGNCiHGNC:10730. SEMA4B.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei718 – 73821HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 4343Sequence analysisAdd
BLAST
Chaini44 – 837794Sequence analysisPRO_5007674839Add
BLAST

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

MaxQBiJ3KNP4.
PeptideAtlasiJ3KNP4.

Expressioni

Gene expression databases

BgeeiENSG00000185033.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000332204.

Structurei

3D structure databases

SMRiJ3KNP4. Positions 46-674.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini47 – 523477SemaInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains Sema domain.SAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3611. Eukaryota.
ENOG410XQZC. LUCA.
GeneTreeiENSGT00760000118854.
KOiK06521.
OMAiACPLLSN.
OrthoDBiEOG091G01W0.
PhylomeDBiJ3KNP4.
TreeFamiTF352903.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR016201. Plexin-like_fold.
IPR002165. Plexin_repeat.
IPR001627. Semap_dom.
IPR027231. Semaphorin.
IPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view]
PANTHERiPTHR11036. PTHR11036. 1 hit.
PfamiPF01437. PSI. 1 hit.
PF01403. Sema. 1 hit.
[Graphical view]
SMARTiSM00423. PSI. 1 hit.
SM00630. Sema. 1 hit.
[Graphical view]
SUPFAMiSSF101912. SSF101912. 1 hit.
SSF103575. SSF103575. 1 hit.
PROSITEiPS51004. SEMA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

J3KNP4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRTAMGLRS WLAAPWGALP PRPPLLLLLL LLLLLQPPPP TWALSPRISL
60 70 80 90 100
PLGSEERPFL RFEAEHISNY TALLLSRDGR TLYVGAREAL FALSSNLSFL
110 120 130 140 150
PGGEYQELLW GADAEKKQQC SFKGKDPQRD CQNYIKILLP LSGSHLFTCG
160 170 180 190 200
TAAFSPMCTY INMENFTLAR DEKGNVLLED GKGRCPFDPN FKSTALVVDG
210 220 230 240 250
ELYTGTVSSF QGNDPAISRS QSLRPTKTES SLNWLQDPAF VASAYIPESL
260 270 280 290 300
GSLQGDDDKI YFFFSETGQE FEFFENTIVS RIARICKGDE GGERVLQQRW
310 320 330 340 350
TSFLKAQLLC SRPDDGFPFN VLQDVFTLSP SPQDWRDTLF YGVFTSQWHR
360 370 380 390 400
GTTEGSAVCV FTMKDVQRVF SGLYKEVNRE TQQWYTVTHP VPTPRPGACI
410 420 430 440 450
TNSARERKIN SSLQLPDRVL NFLKDHFLMD GQVRSRMLLL QPQARYQRVA
460 470 480 490 500
VHRVPGLHHT YDVLFLGTGD GRLHKAVSVG PRVHIIEELQ IFSSGQPVQN
510 520 530 540 550
LLLDTHRGLL YAASHSGVVQ VPMANCSLYR SCGDCLLARD PYCAWSGSSC
560 570 580 590 600
KHVSLYQPQL ATRPWIQDIE GASAKDLCSA SSVVSPSFVP TGEKPCEQVQ
610 620 630 640 650
FQPNTVNTLA CPLLSNLATR LWLRNGAPVN ASASCHVLPT GDLLLVGTQQ
660 670 680 690 700
LGEFQCWSLE EGFQQLVASY CPEVVEDGVA DQTDEGGSVP VIISTSRVSA
710 720 730 740 750
PAGGKASWGA DRSYWKEFLV MCTLFVLAVL LPVLFLLYRH RNSMKVFLKQ
760 770 780 790 800
GECASVHPKT CPVVLPPETR PLNGLGPPST PLDHRGYQSL SDSPPGSRVF
810 820 830
TESEKRPLSI QDSFVEVSPV CPRPRVRLGS EIRDSVV
Length:837
Mass (Da):92,766
Last modified:October 3, 2012 - v1
Checksum:i3C9F27C0E68A1E21
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC091167 Genomic DNA. No translation available.
RefSeqiNP_064595.2. NM_020210.3.
NP_945119.1. NM_198925.2.
UniGeneiHs.474935.

Genome annotation databases

EnsembliENST00000332496; ENSP00000332204; ENSG00000185033.
ENST00000411539; ENSP00000394720; ENSG00000185033.
GeneIDi10509.
KEGGihsa:10509.
UCSCiuc002boy.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC091167 Genomic DNA. No translation available.
RefSeqiNP_064595.2. NM_020210.3.
NP_945119.1. NM_198925.2.
UniGeneiHs.474935.

3D structure databases

SMRiJ3KNP4. Positions 46-674.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000332204.

Proteomic databases

MaxQBiJ3KNP4.
PeptideAtlasiJ3KNP4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000332496; ENSP00000332204; ENSG00000185033.
ENST00000411539; ENSP00000394720; ENSG00000185033.
GeneIDi10509.
KEGGihsa:10509.
UCSCiuc002boy.4. human.

Organism-specific databases

CTDi10509.
HGNCiHGNC:10730. SEMA4B.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3611. Eukaryota.
ENOG410XQZC. LUCA.
GeneTreeiENSGT00760000118854.
KOiK06521.
OMAiACPLLSN.
OrthoDBiEOG091G01W0.
PhylomeDBiJ3KNP4.
TreeFamiTF352903.

Miscellaneous databases

ChiTaRSiSEMA4B. human.
GenomeRNAii10509.

Gene expression databases

BgeeiENSG00000185033.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR016201. Plexin-like_fold.
IPR002165. Plexin_repeat.
IPR001627. Semap_dom.
IPR027231. Semaphorin.
IPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view]
PANTHERiPTHR11036. PTHR11036. 1 hit.
PfamiPF01437. PSI. 1 hit.
PF01403. Sema. 1 hit.
[Graphical view]
SMARTiSM00423. PSI. 1 hit.
SM00630. Sema. 1 hit.
[Graphical view]
SUPFAMiSSF101912. SSF101912. 1 hit.
SSF103575. SSF103575. 1 hit.
PROSITEiPS51004. SEMA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiJ3KNP4_HUMAN
AccessioniPrimary (citable) accession number: J3KNP4
Entry historyi
Integrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: September 7, 2016
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.