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Protein
Submitted name:

Mitochondrial inner membrane protein OXA1L

Gene

OXA1L

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Mitochondrial inner membrane protein OXA1LImported
Gene namesi
Name:OXA1LImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 14

Organism-specific databases

HGNCiHGNC:8526. OXA1L.

Subcellular locationi

  • Membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei198 – 22023HelicalSequence analysisAdd
BLAST
Transmembranei277 – 29418HelicalSequence analysisAdd
BLAST
Transmembranei322 – 34120HelicalSequence analysisAdd
BLAST
Transmembranei362 – 38019HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

EPDiJ3KNA0.

Expressioni

Gene expression databases

ExpressionAtlasiJ3KNA0. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000285848.

Structurei

3D structure databases

SMRiJ3KNA0. Positions 188-389.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the OXA1/ALB3/YidC family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG1239. Eukaryota.
COG0706. LUCA.
GeneTreeiENSGT00530000063506.
KOiK03217.
OMAiMQNHLEL.
OrthoDBiEOG7S4X6H.
PhylomeDBiJ3KNA0.
TreeFamiTF354324.

Family and domain databases

InterProiIPR028055. Membr_insert_YidC/Oxa1_C.
IPR001708. Membrane_insert_OXA1/ALB3/YidC.
[Graphical view]
PANTHERiPTHR12428. PTHR12428. 1 hit.
PfamiPF02096. 60KD_IMP. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03592. yidC_oxa1_cterm. 1 hit.

Sequencei

Sequence statusi: Complete.

J3KNA0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVTWLYRFLP TSNMAAKLRS LLPPDLRLQF WLHARLQKCF LSRGCGSYCA
60 70 80 90 100
GAKASPLPGK MAMGLMCGRR ELLRLLQSGR RVHSVAGPSQ WLGKPLTTRL
110 120 130 140 150
LFPAAPCCCR PHYLFLAASG PRSLSTSAIS FAEVQVQAPP VVAATPSPTA
160 170 180 190 200
VPEVASGETA DVVQTAAEQS FAELGLGSYT PVGLIQNLLE FMHVDLGLPW
210 220 230 240 250
WGAIAACTVF ARCLIFPLIV TGQREAARIH NHLPEIQKFS SRIREAKLAG
260 270 280 290 300
DHIEYYKASS EMALYQKKHG IKLYKPLILP VTQAPIFISF FIALREMANL
310 320 330 340 350
PVPSLQTGGL WWFQDLTVSD PIYILPLAVT ATMWAVLELG AETGVQSSDL
360 370 380 390 400
QWMRNVIRMM PLITLPITMH FPTAVFMYWL SSNLFSLVQV SCLRIPAVRT
410 420 430 440 450
VLKIPQRVVH DLDKLPPREG FLESFKKGWK NAEMTRQLRE REQRMRNQLE
460 470 480 490
LAARGPLRQT FTHNPLLQPG KDNPPNIPSS SSKPKSKYPW HDTLG
Length:495
Mass (Da):55,270
Last modified:October 3, 2012 - v1
Checksum:i90D4CDD582F750B1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL135998 Genomic DNA. No translation available.
RefSeqiNP_005006.3. NM_005015.3.
UniGeneiHs.151134.

Genome annotation databases

EnsembliENST00000285848; ENSP00000285848; ENSG00000155463.
ENST00000612549; ENSP00000483491; ENSG00000155463.
GeneIDi5018.
KEGGihsa:5018.
UCSCiuc001wgn.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL135998 Genomic DNA. No translation available.
RefSeqiNP_005006.3. NM_005015.3.
UniGeneiHs.151134.

3D structure databases

SMRiJ3KNA0. Positions 188-389.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000285848.

Proteomic databases

EPDiJ3KNA0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000285848; ENSP00000285848; ENSG00000155463.
ENST00000612549; ENSP00000483491; ENSG00000155463.
GeneIDi5018.
KEGGihsa:5018.
UCSCiuc001wgn.2. human.

Organism-specific databases

CTDi5018.
HGNCiHGNC:8526. OXA1L.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1239. Eukaryota.
COG0706. LUCA.
GeneTreeiENSGT00530000063506.
KOiK03217.
OMAiMQNHLEL.
OrthoDBiEOG7S4X6H.
PhylomeDBiJ3KNA0.
TreeFamiTF354324.

Miscellaneous databases

ChiTaRSiOXA1L. human.
GenomeRNAii5018.

Gene expression databases

ExpressionAtlasiJ3KNA0. baseline and differential.

Family and domain databases

InterProiIPR028055. Membr_insert_YidC/Oxa1_C.
IPR001708. Membrane_insert_OXA1/ALB3/YidC.
[Graphical view]
PANTHERiPTHR12428. PTHR12428. 1 hit.
PfamiPF02096. 60KD_IMP. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03592. yidC_oxa1_cterm. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence and analysis of human chromosome 14."
    Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C., Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A., Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S., Sun H., Du H.
    , Pepin K., Artiguenave F., Robert C., Cruaud C., Bruels T., Jaillon O., Friedlander L., Samson G., Brottier P., Cure S., Segurens B., Aniere F., Samain S., Crespeau H., Abbasi N., Aiach N., Boscus D., Dickhoff R., Dors M., Dubois I., Friedman C., Gouyvenoux M., James R., Madan A., Mairey-Estrada B., Mangenot S., Martins N., Menard M., Oztas S., Ratcliffe A., Shaffer T., Trask B., Vacherie B., Bellemere C., Belser C., Besnard-Gonnet M., Bartol-Mavel D., Boutard M., Briez-Silla S., Combette S., Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C., Muselet D., Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P., Trybou A., Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M., Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V., Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L., Verdier J., Verdier-Discala C., Hillier L.W., Fulton L., McPherson J., Matsuda F., Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W., Quetier F., Waterston R., Hood L., Weissenbach J.
    Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Ensembl
    Submitted (AUG-2012) to UniProtKB
    Cited for: IDENTIFICATION.
  4. "Toward a comprehensive characterization of a human cancer cell phosphoproteome."
    Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J., Mohammed S.
    J. Proteome Res. 12:260-271(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  5. Ensembl
    Submitted (SEP-2014) to UniProtKB
    Cited for: IDENTIFICATION.
  6. "N-terminome analysis of the human mitochondrial proteome."
    Vaca Jacome A.S., Rabilloud T., Schaeffer-Reiss C., Rompais M., Ayoub D., Lane L., Bairoch A., Van Dorsselaer A., Carapito C.
    Proteomics 15:2519-2524(2015) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiJ3KNA0_HUMAN
AccessioniPrimary (citable) accession number: J3KNA0
Entry historyi
Integrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: June 8, 2016
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.