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Protein
Submitted name:

REST corepressor 1

Gene

RCOR1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
REST corepressor 1Imported
Submitted name:
REST corepressor 1, isoform CRA_aImported
Gene namesi
Name:RCOR1Imported
ORF Names:hCG_24743Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 14

Organism-specific databases

HGNCiHGNC:17441. RCOR1.

Subcellular locationi

  • Nucleus SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000089902.

PTM / Processingi

Proteomic databases

EPDiJ3KN32.
MaxQBiJ3KN32.
PeptideAtlasiJ3KN32.
PRIDEiJ3KN32.

Expressioni

Gene expression databases

BgeeiENSG00000089902.
ExpressionAtlasiJ3KN32. baseline and differential.

Interactioni

Protein-protein interaction databases

IntActiJ3KN32. 3 interactors.
STRINGi9606.ENSP00000459789.

Structurei

3D structure databases

ProteinModelPortaliJ3KN32.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini103 – 189ELM2InterPro annotationAdd BLAST87
Domaini190 – 241SANTInterPro annotationAdd BLAST52
Domaini381 – 432SANTInterPro annotationAdd BLAST52

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili338 – 365Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1194. Eukaryota.
ENOG410XSIS. LUCA.
GeneTreeiENSGT00840000129748.
KOiK11829.
OMAiVKRQIQN.
OrthoDBiEOG091G096Y.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR000949. ELM2_dom.
IPR009057. Homeodomain-like.
IPR001005. SANT/Myb.
IPR017884. SANT_dom.
[Graphical view]
PfamiPF01448. ELM2. 1 hit.
PF00249. Myb_DNA-binding. 1 hit.
[Graphical view]
SMARTiSM01189. ELM2. 1 hit.
SM00717. SANT. 2 hits.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 2 hits.
PROSITEiPS51156. ELM2. 1 hit.
PS51293. SANT. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

J3KN32-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPAMVEKGPE VSGKRRGRNN AAASASAAAA SAAASAACAS PAATAASGAA
60 70 80 90 100
ASSASAAAAS AAAAPNNGQN KSLAAAAPNG NSSSNSWEEG SSGSSSDEEH
110 120 130 140 150
GGGGMRVGPQ YQAVVPDFDP AKLARRSQER DNLGMLVWSP NQNLSEAKLD
160 170 180 190 200
EYIAIAKEKH GYNMEQALGM LFWHKHNIEK SLADLPNFTP FPDEWTVEDK
210 220 230 240 250
VLFEQAFSFH GKTFHRIQQM LPDKSIASLV KFYYSWKKTR TKTSVMDRHA
260 270 280 290 300
RKQKREREES EDELEEANGN NPIDIEVDQN KESKKEVPPT ETVPQVKKEK
310 320 330 340 350
HSTQAKNRAK RKPPKGMFLS QEDVEAVSAN ATAATTVLRQ LDMELVSVKR
360 370 380 390 400
QIQNIKQTNS ALKEKLDGGI EPYRLPEVIQ KCNARWTTEE QLLAVQAIRK
410 420 430 440 450
YGRDFQAISD VIGNKSVVQV KNFFVNYRRR FNIDEVLQEW EAEHGKEETN
460 470 480
GPSNQKPVKS PDNSIKMPEE EDEAPVLDVR YASAS
Length:485
Mass (Da):53,327
Last modified:October 3, 2012 - v1
Checksum:i77E90FB0EFD514B2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL132801 Genomic DNA. No translation available.
AL136293 Genomic DNA. No translation available.
CH471061 Genomic DNA. Translation: EAW81793.1.
RefSeqiNP_055971.2. NM_015156.3.
UniGeneiHs.510521.

Genome annotation databases

EnsembliENST00000262241; ENSP00000262241; ENSG00000089902.
GeneIDi23186.
KEGGihsa:23186.
UCSCiuc001ymb.5. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL132801 Genomic DNA. No translation available.
AL136293 Genomic DNA. No translation available.
CH471061 Genomic DNA. Translation: EAW81793.1.
RefSeqiNP_055971.2. NM_015156.3.
UniGeneiHs.510521.

3D structure databases

ProteinModelPortaliJ3KN32.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiJ3KN32. 3 interactors.
STRINGi9606.ENSP00000459789.

Proteomic databases

EPDiJ3KN32.
MaxQBiJ3KN32.
PeptideAtlasiJ3KN32.
PRIDEiJ3KN32.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000262241; ENSP00000262241; ENSG00000089902.
GeneIDi23186.
KEGGihsa:23186.
UCSCiuc001ymb.5. human.

Organism-specific databases

CTDi23186.
HGNCiHGNC:17441. RCOR1.
OpenTargetsiENSG00000089902.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1194. Eukaryota.
ENOG410XSIS. LUCA.
GeneTreeiENSGT00840000129748.
KOiK11829.
OMAiVKRQIQN.
OrthoDBiEOG091G096Y.

Miscellaneous databases

ChiTaRSiRCOR1. human.
GenomeRNAii23186.

Gene expression databases

BgeeiENSG00000089902.
ExpressionAtlasiJ3KN32. baseline and differential.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR000949. ELM2_dom.
IPR009057. Homeodomain-like.
IPR001005. SANT/Myb.
IPR017884. SANT_dom.
[Graphical view]
PfamiPF01448. ELM2. 1 hit.
PF00249. Myb_DNA-binding. 1 hit.
[Graphical view]
SMARTiSM01189. ELM2. 1 hit.
SM00717. SANT. 2 hits.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 2 hits.
PROSITEiPS51156. ELM2. 1 hit.
PS51293. SANT. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiJ3KN32_HUMAN
AccessioniPrimary (citable) accession number: J3KN32
Entry historyi
Integrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: November 30, 2016
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.