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J3KN16

- J3KN16_HUMAN

UniProt

J3KN16 - J3KN16_HUMAN

Protein
Submitted name:

Proteasome-associated protein ECM29 homolog

Gene

KIAA0368

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 16 (01 Oct 2014)
      Sequence version 1 (03 Oct 2012)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Proteasome-associated protein ECM29 homologImported
    Gene namesi
    Name:KIAA0368Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 9

    Organism-specific databases

    HGNCiHGNC:29020. KIAA0368.

    PTM / Processingi

    Proteomic databases

    MaxQBiJ3KN16.
    PRIDEiJ3KN16.

    Expressioni

    Gene expression databases

    ArrayExpressiJ3KN16.

    Interactioni

    Protein-protein interaction databases

    IntActiJ3KN16. 1 interaction.

    Structurei

    3D structure databases

    ProteinModelPortaliJ3KN16.
    SMRiJ3KN16. Positions 587-623, 1353-1380.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    KOiK11886.
    OMAiMYCLLEV.
    PhylomeDBiJ3KN16.
    TreeFamiTF314213.

    Family and domain databases

    Gene3Di1.25.10.10. 6 hits.
    InterProiIPR011989. ARM-like.
    IPR016024. ARM-type_fold.
    IPR026827. ECM29/GCN1.
    IPR024372. Proteasome_stabil_ECM29.
    [Graphical view]
    PANTHERiPTHR23346. PTHR23346. 1 hit.
    PTHR23346:SF19. PTHR23346:SF19. 1 hit.
    PfamiPF13001. Ecm29. 1 hit.
    [Graphical view]
    SUPFAMiSSF48371. SSF48371. 7 hits.

    Sequencei

    Sequence statusi: Complete.

    J3KN16-1 [UniParc]FASTAAdd to Basket

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    MTSRTKRRQK VKISISKINH SSYRKEHRPF WEHQPPPHQN WAVGGRCGAG     50
    ARPGLSQRRG REVRREAQGG ASSRRLRARL YFSESTSLPL DRRGSPGPLG 100
    PAPHGLRRAA PRGPARRTPR STALTSRRRA QRPRHGDRLR LRSEARPRAA 150
    GDWPCARGGA VRPGRPHRPP RVESARGAHA GRAATDQLER VFLRLGHAET 200
    DEQLQNIISK FLPPVLLKLS STQEGVRKKV MELLVHLNKR IKSRPKIQLP 250
    VETLLVQYQD PAAVSFVTNF TIIYVKMGYP RLPVEKQCEL APTLLTAMEG 300
    KPQPQQDSLM HLLIPTLFHM KYPVESSKSA SPFNLAEKPK TVQLLLDFML 350
    DVLLMPYGYV LNESQSRQNS SSAQGSSSNS GGGSGIPQPP PGMSFYAAKR 400
    VIGDNPWTPE QLEQCKLGIV KFIEAEQVPE LEAVLHLVIA SSDTRHSVAT 450
    AADLELKSKQ SLIDWNNPAI INKMYKVYLG DIPLKTKEGA VLKPELKRDP 500
    VSTRVKLKIV PHLLRSRQAA ETFPANIQVV YDGLFGTNTN SKLRTLSLQF 550
    VHHICITCPE IKIKPLGPML LNGLTKLINE YKEDPKLLSM AYSAVGKLSS 600
    RMPHLFTKDI ALVQQLFEAL CKEEPETRLA IQEALSMMVG AYSTLEGAQR 650
    TLMEALVASY LIKPEVQVRQ VAVKFASTVF PSDHIPSRYL LLLAAGDPRE 700
    EVHGEAQRVL RCLPGRNRKE STSEQMPSFP EMVYYIQEKA SHRMKTPVKY 750
    MTGTTVLPFN PAAFGEIVLY LRMCLAHSAG VVPTSQSLAD MQDHAPAIGR 800
    YIRTLMSSGQ MAPSSSNKSG ETNPVQIYIG LLQQLLAGVG GLPVMYCLLE 850
    AVSVYPEKLA TKFVDKTEWI KSLMNNSKEE MRELAALFYS VVVSTVSGNE 900
    LKSMIEQLIK TTKDNHSPEI QHGSLLALGF TVGRYLAKKK MRMSEQQDLE 950
    RNADTLPDQE ELIQSATETI GSFLDSTSPL LAIAACTALG EIGRNGPLPI 1000
    PSEGSGFTKL HLVESLLSRI PSSKETNKMK ERAIQTLGYF PVGDGDFPHQ 1050
    KLLLQGLMDS VEAKQIELQF TIGEAITSAA IGTSSVAARD AWQMTEEEYT 1100
    PPAGAKVNDV VPWVLDVILN KHIISPNPHV RQAACIWLLS LVRKLSTHKE 1150
    VKSHLKEIQS AFVSVLSEND ELSQDVASKG LGLVYELGNE QDQQELVSTL 1200
    VETLMTGKRV KHEVSGETVV FQGGALGKTP DGQGLSTYKE LCSLASDLSQ 1250
    PDLVYKFMNL ANHHAMWNSR KGAAFGFNVI ATRAGEQLAP FLPQLVPRLY 1300
    RYQFDPNLGI RQAMTSIWNA LVTDKSMVDK YLKEILQDLV KNLTSNMWRV 1350
    RESSCLALND LLRGRPLDDI IDKLPEIWET LFRVQDDIKE SVRKAAELAL 1400
    KTLSKVCVKM CDPAKGAAGQ RTIAALLPCL LDKGMMSTVT EVRALSINTL 1450
    VKISKSAGAM LKPHAPKLIP ALLESLSVLE PQVLNYLSLR ATEQEKAAMD 1500
    SARLSAAKSS PMMETINMCL QYLDVSVLGE LVPRLCELIR SGVGLGTKGG 1550
    CASVIVSLTT QCPQDLTPYS GKLMSALLSG LTDRNSVIQK SCAFAMGHLV 1600
    RTSRDSSTEK LLQKLNGWYM EKEEPIYKTS CALTIHAIGR YSPDVLKNHA 1650
    KEVLPLAFLG MHEIADEEKS EKEECNLWTE VWQENVPGSF GGIRLYLQEL 1700
    ITITQKALQS QSWKMKAQGA IAMASIAKQT SSLVPPYLGM ILTALLQGLA 1750
    GRTWAGKEEL LKAIACVVTA CSAELEKSVP NQPSTNEILQ AVLKECSKEN 1800
    VKYKIVAISC AADILKATKE DRFQEFSNIV IPLIKKNSLE SSGVRTTKNE 1850
    EENEKEKELQ LEYLLGAFES LGKAWPRNAE TQRCYRQELC KLMCERLKLS 1900
    TWKVQLGVLQ SMNAFFQGLM LLEEEHADPE ALAEILLETC KSITYSLENK 1950
    TYSSVRTEAL SVIELLLKKL EESKQWECLT SECRVLLIES LATMEPDSRP 2000
    ELQEKAALLK KTLENLE 2017
    Length:2,017
    Mass (Da):223,694
    Last modified:October 3, 2012 - v1
    Checksum:i0194A2BDED3768EC
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL159168 Genomic DNA. No translation available.
    AL354661 Genomic DNA. No translation available.
    RefSeqiNP_001073867.1. NM_001080398.1.
    UniGeneiHs.368255.

    Genome annotation databases

    EnsembliENST00000259335; ENSP00000259335; ENSG00000136813.
    GeneIDi23392.
    KEGGihsa:23392.
    UCSCiuc004bfe.1. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL159168 Genomic DNA. No translation available.
    AL354661 Genomic DNA. No translation available.
    RefSeqi NP_001073867.1. NM_001080398.1.
    UniGenei Hs.368255.

    3D structure databases

    ProteinModelPortali J3KN16.
    SMRi J3KN16. Positions 587-623, 1353-1380.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi J3KN16. 1 interaction.

    Proteomic databases

    MaxQBi J3KN16.
    PRIDEi J3KN16.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000259335 ; ENSP00000259335 ; ENSG00000136813 .
    GeneIDi 23392.
    KEGGi hsa:23392.
    UCSCi uc004bfe.1. human.

    Organism-specific databases

    CTDi 23392.
    HGNCi HGNC:29020. KIAA0368.
    HUGEi Search...
    GenAtlasi Search...

    Phylogenomic databases

    KOi K11886.
    OMAi MYCLLEV.
    PhylomeDBi J3KN16.
    TreeFami TF314213.

    Miscellaneous databases

    GenomeRNAii 23392.
    NextBioi 35534791.

    Gene expression databases

    ArrayExpressi J3KN16.

    Family and domain databases

    Gene3Di 1.25.10.10. 6 hits.
    InterProi IPR011989. ARM-like.
    IPR016024. ARM-type_fold.
    IPR026827. ECM29/GCN1.
    IPR024372. Proteasome_stabil_ECM29.
    [Graphical view ]
    PANTHERi PTHR23346. PTHR23346. 1 hit.
    PTHR23346:SF19. PTHR23346:SF19. 1 hit.
    Pfami PF13001. Ecm29. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48371. SSF48371. 7 hits.
    ProtoNeti Search...

    Publicationsi

    1. "DNA sequence and analysis of human chromosome 9."
      Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L.
      , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I.
      Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
      Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    4. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
      Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    5. Ensembl
      Submitted (AUG-2012) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiJ3KN16_HUMAN
    AccessioniPrimary (citable) accession number: J3KN16
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 3, 2012
    Last sequence update: October 3, 2012
    Last modified: October 1, 2014
    This is version 16 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3