J3KIC6 (J3KIC6_COCIM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Hexokinase EMBL EAS35711.2

Gene names

ORF Names:

CIMG_00997 EMBL EAS35711.2

Organism

Coccidioides immitis (strain RS) (Valley fever fungus) [Reference proteome] EMBL EAS35711.2

Taxonomic identifier

246410 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Pezizomycotina › leotiomyceta › Eurotiomycetes › Eurotiomycetidae › Onygenales › mitosporic Onygenales › Coccidioides › Coccidioides immitis

Protein attributes

Sequence length	490 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the hexokinase family. RuleBase RU004510

Ontologies

Keywords
Biological process	Glycolysis SAAS SAAS022672 RuleBase RU004049
Ligand	ATP-binding SAAS SAAS022672 RuleBase RU004049 Nucleotide-binding
Molecular function	Kinase SAAS SAAS022672 RuleBase RU004049 EMBL EAS35711.2 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW hexokinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	J3KIC6 [UniParc]. Last modified October 3, 2012. Version 1. Checksum: 64D1F29C94EC72A7	FASTA	490	54,461
	10 20 30 40 50 60 MTVTAPRRRP SRKGSMADMP KDLLEQVKEL EELFTVDQAR LKKIVDHFVK ELEKGLSVQG 70 80 90 100 110 120 GNIPMNVTWV MGFPTGHEHG TFLALDMGGT NLRVCEIFLC EKKGEFDITQ SKYRIPEELK 130 140 150 160 170 180 SGNADDLWEY IADCVQQFIE YHHEEENLPD LPLGFTFSYP ATQEYIDHGV LQRWTKGFDI 190 200 210 220 230 240 DGVEGEDVVP MLEAALAKRG LPIKVAALIN DTTGTLIASA YTDPEMRIGC IFGTGVNAAY 250 260 270 280 290 300 MENAGSIPKI AHYNLPPDMP IAINCEYGAF DNERVVLPLT QYDVVIDRDS PRPGQQAFEK 310 320 330 340 350 360 MTAGLYLGEI FRLVLLDLID NKGNLIFEGQ DVSSLRKPYC LDSSFLAYIE EDPFENLSET 370 380 390 400 410 420 RDLFERTLGI KATKPELELC RRLAELVGTR AARLSACGVA AICKKKNIKS CHVGADGSVF 430 440 450 460 470 480 NKYPHFKARG AKALREILDW ADDEEDKVII CSAEDGSGVG AALIAALTLE RVKQGNLAGI 490 RKTDTMKKLL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Comparative genomic analyses of the human fungal pathogens Coccidioides and their relatives." Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R., Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y., McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M., Barker B.M., Galgiani J.N. , Orbach M.J., Kirkland T.N., Cole G.T., Henn M.R., Birren B.W., Taylor J.W. Genome Res. 19:1722-1731(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: RS.
[2]	"Population genomic sequencing of Coccidioides fungi reveals recent hybridization and transposon control." Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J., Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D., Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A., FitzGerald M. , Lui A., Macdonald J.P., Priest M., Orbach M.J., Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R., Taylor J.W., Rounsley S.D. Genome Res. 20:938-946(2010) [PubMed] [Europe PMC] [Abstract] Cited for: GENOME REANNOTATION. Strain: RS.

Cross-references

Sequence databases
EMBL GenBank DDBJ	GG704911 Genomic DNA. Translation: EAS35711.2.
RefSeq	XP_001247226.1. XM_001247225.1. XP_001247294.1. XM_001247293.1.
3D structure databases
ProteinModelPortal	J3KIC6.
SMR	J3KIC6. Positions 18-481.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4565527. 4567493.
KEGG	cim:CIMG_00997. cim:CIMG_01065.
Phylogenomic databases
KO	K00844.
Family and domain databases
InterPro	IPR001312. Hexokinase. IPR022673. Hexokinase_C. IPR019807. Hexokinase_CS. IPR022672. Hexokinase_N. [Graphical view]
PANTHER	PTHR19443. PTHR19443. 1 hit.
Pfam	PF00349. Hexokinase_1. 1 hit. PF03727. Hexokinase_2. 1 hit. [Graphical view]
PRINTS	PR00475. HEXOKINASE.
PROSITE	PS00378. HEXOKINASES. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

J3KIC6_COCIM

Accession

Primary (citable) accession number: J3KIC6

Entry history

Integrated into UniProtKB/TrEMBL:	October 3, 2012
Last sequence update:	October 3, 2012
Last modified:	May 1, 2013
This is version 7 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)