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Protein

Hexokinase

Gene

CIMG_00997

Organism
Coccidioides immitis (strain RS) (Valley fever fungus)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-hexose = ADP + D-hexose 6-phosphate.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. hexokinase activity Source: UniProtKB-EC

GO - Biological processi

  1. glycolytic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
HexokinaseUniRule annotation (EC:2.7.1.1UniRule annotation)
Gene namesi
ORF Names:CIMG_00997Imported
OrganismiCoccidioides immitis (strain RS) (Valley fever fungus)Imported
Taxonomic identifieri246410 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesmitosporic OnygenalesCoccidioides
ProteomesiUP000001261 Componenti: Unassembled WGS sequence

Structurei

3D structure databases

ProteinModelPortaliJ3KIC6.
SMRiJ3KIC6. Positions 18-481.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation

Phylogenomic databases

InParanoidiJ3KIC6.
KOiK00844.
OrthoDBiEOG79SF68.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

J3KIC6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTVTAPRRRP SRKGSMADMP KDLLEQVKEL EELFTVDQAR LKKIVDHFVK
60 70 80 90 100
ELEKGLSVQG GNIPMNVTWV MGFPTGHEHG TFLALDMGGT NLRVCEIFLC
110 120 130 140 150
EKKGEFDITQ SKYRIPEELK SGNADDLWEY IADCVQQFIE YHHEEENLPD
160 170 180 190 200
LPLGFTFSYP ATQEYIDHGV LQRWTKGFDI DGVEGEDVVP MLEAALAKRG
210 220 230 240 250
LPIKVAALIN DTTGTLIASA YTDPEMRIGC IFGTGVNAAY MENAGSIPKI
260 270 280 290 300
AHYNLPPDMP IAINCEYGAF DNERVVLPLT QYDVVIDRDS PRPGQQAFEK
310 320 330 340 350
MTAGLYLGEI FRLVLLDLID NKGNLIFEGQ DVSSLRKPYC LDSSFLAYIE
360 370 380 390 400
EDPFENLSET RDLFERTLGI KATKPELELC RRLAELVGTR AARLSACGVA
410 420 430 440 450
AICKKKNIKS CHVGADGSVF NKYPHFKARG AKALREILDW ADDEEDKVII
460 470 480 490
CSAEDGSGVG AALIAALTLE RVKQGNLAGI RKTDTMKKLL
Length:490
Mass (Da):54,461
Last modified:October 3, 2012 - v1
Checksum:i64D1F29C94EC72A7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG704911 Genomic DNA. Translation: EAS35711.2.
RefSeqiXP_001247226.1. XM_001247225.1.
XP_001247294.1. XM_001247293.1.

Genome annotation databases

GeneIDi4565527.
4567493.
KEGGicim:CIMG_00997.
cim:CIMG_01065.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG704911 Genomic DNA. Translation: EAS35711.2.
RefSeqiXP_001247226.1. XM_001247225.1.
XP_001247294.1. XM_001247293.1.

3D structure databases

ProteinModelPortaliJ3KIC6.
SMRiJ3KIC6. Positions 18-481.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi4565527.
4567493.
KEGGicim:CIMG_00997.
cim:CIMG_01065.

Phylogenomic databases

InParanoidiJ3KIC6.
KOiK00844.
OrthoDBiEOG79SF68.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RSImported.
  2. Cited for: GENOME REANNOTATION.
    Strain: RSImported.

Entry informationi

Entry nameiJ3KIC6_COCIM
AccessioniPrimary (citable) accession number: J3KIC6
Entry historyi
Integrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: April 29, 2015
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.