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Protein

Histone-lysine N-methyltransferase

Gene

CIMG_00441

Organism
Coccidioides immitis (strain RS) (Valley fever fungus)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotationSAAS annotation, Transferase

Keywords - Ligandi

S-adenosyl-L-methionineSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone-lysine N-methyltransferaseSAAS annotation (EC:2.1.1.43SAAS annotation)
Gene namesi
ORF Names:CIMG_00441Imported
OrganismiCoccidioides immitis (strain RS) (Valley fever fungus)Imported
Taxonomic identifieri246410 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesmitosporic OnygenalesCoccidioides
ProteomesiUP000001261 Componenti: Unassembled WGS sequence

Subcellular locationi

Keywords - Cellular componenti

NucleusSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi246410.XP_001246653.1.

Family & Domainsi

Sequence similaritiesi

Contains 1 SET domain.UniRule annotation
Contains 1 post-SET domain.UniRule annotation

Phylogenomic databases

InParanoidiJ3KH04.
KOiK06101.
K14784.
OrthoDBiEOG725DV9.

Family and domain databases

InterProiIPR006560. AWS_dom.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
[Graphical view]
PfamiPF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00570. AWS. 1 hit.
SM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
PROSITEiPS51215. AWS. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

J3KH04-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARDPMLSPS STPTSSALDS DATAIDATVP VLTPATSISE QSTPVDTEKD
60 70 80 90 100
GEHRAKKAKA SRRVTRSSLK NGELEANGGG EAMVTRPNDE SLDNTNTQED
110 120 130 140 150
EDCTSLLNGA EDASGSVDKW SSKNAEAAGK KPNKKAGNKS PKRRSTRLSL
160 170 180 190 200
LAKTMDLAQS APSVLGKRTL DAISKSKDKV KTIDRKASLR PRVENEKKEA
210 220 230 240 250
STPAPQEPSP KKRRVSGDNK STCQVPRQEQ TATRENSLIR QKRKPWLKHG
260 270 280 290 300
LYAGQEYIDS SVPKSKRGTR DAKNNGQQSQ VFPFPMYAGA RLLENGRAYK
310 320 330 340 350
LPFDIFSPLP HGQPKPNEWR KANKNVFVGD AASIWKAAKI KEHSTCTCTP
360 370 380 390 400
ETGCDENCQN RYMFYECDDT NCKLGSELCR NRPFSALRRR AKAGGKFNIG
410 420 430 440 450
VEVIKTEDRG YGVRSNRSFD PNQIIVEYTG EILTQEECER RMRTVYKKNE
460 470 480 490 500
CYYLMYFDQN MVIDATRGSI ARFINHSCEP NCRMEKWTVA GKPRMALFAG
510 520 530 540 550
EDGIMTGEEL TYDYNFDPYS QKNVQECRCG APTCRGVLGP RPKESWKNKD
560 570 580 590 600
KEKKSAPAAK RKVDSALDES ASRLNKKPKP SRASSLKTGI KKAVSKARTA
610 620 630 640 650
LKSTQTKGKV KRVGRPAKKA VSIKPIPVKK RRSTLTRAKM PVKSASKSAE
660 670 680 690 700
GDEKPPRNKG RKLKMPSKPR LGNSIAAARA SNKTPALMRK FLEAGDTKGG
710 720 730 740
AKVVSDTIKP GRKTRAARTA DVRSSPDNVP VSRKRGRAKK TS
Length:742
Mass (Da):81,952
Last modified:May 27, 2015 - v2
Checksum:i77768818AE806A65
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG704911 Genomic DNA. Translation: EAS35087.3.
RefSeqiXP_001246653.1. XM_001246652.1.
XP_001246670.1. XM_001246669.1.

Genome annotation databases

GeneIDi4566133.
4566138.
KEGGicim:CIMG_00424.
cim:CIMG_00441.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG704911 Genomic DNA. Translation: EAS35087.3.
RefSeqiXP_001246653.1. XM_001246652.1.
XP_001246670.1. XM_001246669.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi246410.XP_001246653.1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi4566133.
4566138.
KEGGicim:CIMG_00424.
cim:CIMG_00441.

Phylogenomic databases

InParanoidiJ3KH04.
KOiK06101.
K14784.
OrthoDBiEOG725DV9.

Family and domain databases

InterProiIPR006560. AWS_dom.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
[Graphical view]
PfamiPF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00570. AWS. 1 hit.
SM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
PROSITEiPS51215. AWS. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RSImported.
  2. Cited for: GENOME REANNOTATION.
    Strain: RSImported.

Entry informationi

Entry nameiJ3KH04_COCIM
AccessioniPrimary (citable) accession number: J3KH04
Entry historyi
Integrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: May 27, 2015
Last modified: June 24, 2015
This is version 14 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.