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Protein

DNA ligase

Gene

CIMG_03804

Organism
Coccidioides immitis (strain RS) (Valley fever fungus)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA biosynthetic process Source: InterPro
  2. DNA ligation involved in DNA repair Source: InterPro
  3. DNA recombination Source: UniProtKB-KW
  4. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationImported

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:CIMG_03804Imported
OrganismiCoccidioides immitis (strain RS) (Valley fever fungus)Imported
Taxonomic identifieri246410 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesmitosporic OnygenalesCoccidioides
ProteomesiUP000001261 Componenti: Unassembled WGS sequence

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

InParanoidiJ3KCI5.
KOiK10747.
OrthoDBiEOG7TXKRG.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

J3KCI5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNPVRKRKR GDPGDPPRTF RSIDSFFKSP RKQPHEADCR IPKSPSEHQL
60 70 80 90 100
LTDEELARKL QAEWDNDASS NFRNATPTNS DENQAPPSQD MKASDGQDPI
110 120 130 140 150
PAPPKSCVFA SSKKKKSVLS LQTSTSAEDT ISMSLPLDQP PLTFSPSLYL
160 170 180 190 200
DKLREFWNTE GGHASYSILA RAFSLVNSTQ SRIRIVDILV NLLRILIEGD
210 220 230 240 250
PDSLLPAVWL ATNAFAPPYV PLELGLGGSA ISKALKKAYG LDNLGLKTLY
260 270 280 290 300
DKYGDAGDVA YEAKKKQSFT LRRPKPLSIK GVYDSLMKIA NSKGTGSQEN
310 320 330 340 350
KQRLVEQLLR DARGAEESRY IVRTLVQHLR IGAVRTTMLI ALARAFLYSR
360 370 380 390 400
PPSASYRVHT NADLMKLKRD ELASLYAKAE EMIKASYARH PNYNDLIPCL
410 420 430 440 450
LATGISEAVL AKCGLALHVP LLPMLGSITR DLTEMLTKLQ GRKFSCEYKY
460 470 480 490 500
DGQRAQVHCD SSGKVSLFSR HLELMTDKYP DLVSLVPQIR GDGVSSFILE
510 520 530 540 550
GEVVAVDQES GVLLPFQTLS NRAKKNVEIG DIKINVCLFA FDLMYLNGEA
560 570 580 590 600
LLERPFRERR ELLRSLFVEI PNRFSWVKSI DATSSESETI LNFFQEATNA
610 620 630 640 650
KCEGIMVKVL DDGTDGEASG ILTSEESSNI SGEKQKASRR RTLLSTYEPD
660 670 680 690 700
KRLDSWLKVK KDYNAAFDTL DLIPIAGWHG QGRKAQWWSP ILLAVRNPET
710 720 730 740 750
GSLEAVTKCM SGFTDKFYQE NKEKYAENGN NTIPRPSYVE YRNEPEVWFE
760 770 780 790 800
PQEVWEIAFA DITLSPTYTA AIGMASEERG LSLRFPRFLR VREDKTIEEA
810 820 830
STSSTLAELW KKQMARLQSE GADLPQEEEN G
Length:831
Mass (Da):93,023
Last modified:October 3, 2012 - v1
Checksum:i307EC902F796CF5D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG704916 Genomic DNA. Translation: EAS32950.2.
RefSeqiXP_001244363.1. XM_001244362.1.
XP_001244533.1. XM_001244532.1.

Genome annotation databases

GeneIDi4562844.
4563017.
KEGGicim:CIMG_03804.
cim:CIMG_03974.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG704916 Genomic DNA. Translation: EAS32950.2.
RefSeqiXP_001244363.1. XM_001244362.1.
XP_001244533.1. XM_001244532.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi4562844.
4563017.
KEGGicim:CIMG_03804.
cim:CIMG_03974.

Phylogenomic databases

InParanoidiJ3KCI5.
KOiK10747.
OrthoDBiEOG7TXKRG.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RSImported.
  2. Cited for: GENOME REANNOTATION.
    Strain: RSImported.

Entry informationi

Entry nameiJ3KCI5_COCIM
AccessioniPrimary (citable) accession number: J3KCI5
Entry historyi
Integrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: April 29, 2015
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.