J3KCI5 (J3KCI5_COCIM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
DNA ligase RuleBase RU000617
EC=6.5.1.1 RuleBase RU000617

Gene names

ORF Names:

CIMG_03804 EMBL EAS32950.2

Organism

Coccidioides immitis (strain RS) (Valley fever fungus) [Reference proteome] EMBL EAS32950.2

Taxonomic identifier

246410 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Pezizomycotina › leotiomyceta › Eurotiomycetes › Eurotiomycetidae › Onygenales › mitosporic Onygenales › Coccidioides › Coccidioides immitis

Protein attributes

Sequence length	831 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). RuleBase RU000617
Sequence similarities	Belongs to the ATP-dependent DNA ligase family. RuleBase RU004196

Ontologies

Keywords
Biological process	DNA damage DNA recombination RuleBase RU000617 DNA repair RuleBase RU000617 DNA replication RuleBase RU000617
Ligand	ATP-binding RuleBase RU000617 Nucleotide-binding
Molecular function	Ligase RuleBase RU000617 EMBL EAS32950.2
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	DNA ligation involved in DNA repair Inferred from electronic annotation. Source: InterPro DNA recombination Inferred from electronic annotation. Source: UniProtKB-KW DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA binding Inferred from electronic annotation. Source: InterPro DNA ligase (ATP) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	J3KCI5 [UniParc]. Last modified October 3, 2012. Version 1. Checksum: 307EC902F796CF5D	FASTA	831	93,023
	10 20 30 40 50 60 MSNPVRKRKR GDPGDPPRTF RSIDSFFKSP RKQPHEADCR IPKSPSEHQL LTDEELARKL 70 80 90 100 110 120 QAEWDNDASS NFRNATPTNS DENQAPPSQD MKASDGQDPI PAPPKSCVFA SSKKKKSVLS 130 140 150 160 170 180 LQTSTSAEDT ISMSLPLDQP PLTFSPSLYL DKLREFWNTE GGHASYSILA RAFSLVNSTQ 190 200 210 220 230 240 SRIRIVDILV NLLRILIEGD PDSLLPAVWL ATNAFAPPYV PLELGLGGSA ISKALKKAYG 250 260 270 280 290 300 LDNLGLKTLY DKYGDAGDVA YEAKKKQSFT LRRPKPLSIK GVYDSLMKIA NSKGTGSQEN 310 320 330 340 350 360 KQRLVEQLLR DARGAEESRY IVRTLVQHLR IGAVRTTMLI ALARAFLYSR PPSASYRVHT 370 380 390 400 410 420 NADLMKLKRD ELASLYAKAE EMIKASYARH PNYNDLIPCL LATGISEAVL AKCGLALHVP 430 440 450 460 470 480 LLPMLGSITR DLTEMLTKLQ GRKFSCEYKY DGQRAQVHCD SSGKVSLFSR HLELMTDKYP 490 500 510 520 530 540 DLVSLVPQIR GDGVSSFILE GEVVAVDQES GVLLPFQTLS NRAKKNVEIG DIKINVCLFA 550 560 570 580 590 600 FDLMYLNGEA LLERPFRERR ELLRSLFVEI PNRFSWVKSI DATSSESETI LNFFQEATNA 610 620 630 640 650 660 KCEGIMVKVL DDGTDGEASG ILTSEESSNI SGEKQKASRR RTLLSTYEPD KRLDSWLKVK 670 680 690 700 710 720 KDYNAAFDTL DLIPIAGWHG QGRKAQWWSP ILLAVRNPET GSLEAVTKCM SGFTDKFYQE 730 740 750 760 770 780 NKEKYAENGN NTIPRPSYVE YRNEPEVWFE PQEVWEIAFA DITLSPTYTA AIGMASEERG 790 800 810 820 830 LSLRFPRFLR VREDKTIEEA STSSTLAELW KKQMARLQSE GADLPQEEEN G

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Comparative genomic analyses of the human fungal pathogens Coccidioides and their relatives." Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R., Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y., McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M., Barker B.M., Galgiani J.N. , Orbach M.J., Kirkland T.N., Cole G.T., Henn M.R., Birren B.W., Taylor J.W. Genome Res. 19:1722-1731(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: RS.
[2]	"Population genomic sequencing of Coccidioides fungi reveals recent hybridization and transposon control." Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J., Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D., Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A., FitzGerald M. , Lui A., Macdonald J.P., Priest M., Orbach M.J., Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R., Taylor J.W., Rounsley S.D. Genome Res. 20:938-946(2010) [PubMed] [Europe PMC] [Abstract] Cited for: GENOME REANNOTATION. Strain: RS.

Cross-references

Sequence databases
EMBL GenBank DDBJ	GG704916 Genomic DNA. Translation: EAS32950.2.
RefSeq	XP_001244363.1. XM_001244362.1. XP_001244533.1. XM_001244532.1.
3D structure databases
ProteinModelPortal	J3KCI5.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4562844. 4563017.
KEGG	cim:CIMG_03804. cim:CIMG_03974.
Phylogenomic databases
KO	K10747.
Family and domain databases
Gene3D	1.10.3260.10. 1 hit. 2.40.50.140. 1 hit.
InterPro	IPR000977. DNA_ligase_ATP-dep. IPR012309. DNA_ligase_ATP-dep_C. IPR012310. DNA_ligase_ATP-dep_cent. IPR016059. DNA_ligase_ATP-dep_CS. IPR012308. DNA_ligase_ATP-dep_N. IPR012340. NA-bd_OB-fold. [Graphical view]
Pfam	PF04679. DNA_ligase_A_C. 1 hit. PF01068. DNA_ligase_A_M. 1 hit. PF04675. DNA_ligase_A_N. 1 hit. [Graphical view]
SUPFAM	SSF50249. Nucleic_acid_OB. 1 hit. SSF117018. SSF117018. 1 hit.
TIGRFAMs	TIGR00574. dnl1. 1 hit.
PROSITE	PS00697. DNA_LIGASE_A1. 1 hit. PS50160. DNA_LIGASE_A3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

J3KCI5_COCIM

Accession

Primary (citable) accession number: J3KCI5

Entry history

Integrated into UniProtKB/TrEMBL:	October 3, 2012
Last sequence update:	October 3, 2012
Last modified:	April 3, 2013
This is version 6 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)