J3KAC9 (J3KAC9_COCIM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Glutamate decarboxylase EMBL EAS31963.2

Gene names

ORF Names:

CIMG_02821 EMBL EAS31963.2

Organism

Coccidioides immitis (strain RS) (Valley fever fungus) [Reference proteome] EMBL EAS31963.2

Taxonomic identifier

246410 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Pezizomycotina › leotiomyceta › Eurotiomycetes › Eurotiomycetidae › Onygenales › mitosporic Onygenales › Coccidioides › Coccidioides immitis

Protein attributes

Sequence length	517 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000382
Sequence similarities	Belongs to the group II decarboxylase family. RuleBase RU000382

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU000382
Molecular function	Lyase RuleBase RU000382
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	glutamate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	glutamate decarboxylase activity Inferred from electronic annotation. Source: InterPro pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	J3KAC9 [UniParc]. Last modified October 3, 2012. Version 1. Checksum: A745D3B254A4FAFC	FASTA	517	58,826
	10 20 30 40 50 60 MVHLAAVRKN SEVLPLRMVK RVDTIPLEEP QEHDFFSSVY GSRFAAEDLP THEMPEKEMP 70 80 90 100 110 120 REVAYRMIKD ELSLDGNPML NLASFVTTYM EEEAERLMAE SFSKNFIDYE EYPQSAEIQN 130 140 150 160 170 180 RCVNMIARLF NAPASDESDH AMGTSCVGSS EAIMLGTLAM KKRWQNKRKA EGKDYSRPNI 190 200 210 220 230 240 IMSSAVQVCW EKAARYFDVE EKFVYCTSER YVIDPEEAIS MVDENTIGIC AILGTTYTGQ 250 260 270 280 290 300 YEDIKALNDI MIEKGIDCPI HVDAASGGFV APFVNPNLEW DFRLEKVVSI NVSGHKYGLV 310 320 330 340 350 360 YPGVGWVVWR SPEYLPKELV FNINYLGANQ ASFTLNFSKG ASQVIGQYYQ MIRLGKRGYR 370 380 390 400 410 420 SIMVNLTRTA DYLASALRQL GFIIMSDGKG HGLPLVAFRL NPDDENVMYD EFALAHQLRE 430 440 450 460 470 480 RGWVVPAYTM APHSEKLKLM RIVVREDFSK SRCDNLVNDI KLALQQLSDM DKRTLEKFQQ 490 500 510 HIRRHVTNSG SATHNHPQYQ DEDHSLQGKT GKTHAIC

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Comparative genomic analyses of the human fungal pathogens Coccidioides and their relatives." Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R., Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y., McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M., Barker B.M., Galgiani J.N. , Orbach M.J., Kirkland T.N., Cole G.T., Henn M.R., Birren B.W., Taylor J.W. Genome Res. 19:1722-1731(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: RS.
[2]	"Population genomic sequencing of Coccidioides fungi reveals recent hybridization and transposon control." Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J., Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D., Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A., FitzGerald M. , Lui A., Macdonald J.P., Priest M., Orbach M.J., Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R., Taylor J.W., Rounsley S.D. Genome Res. 20:938-946(2010) [PubMed] [Europe PMC] [Abstract] Cited for: GENOME REANNOTATION. Strain: RS.

Cross-references

Sequence databases
EMBL GenBank DDBJ	GG704911 Genomic DNA. Translation: EAS31963.2.
RefSeq	XP_001243546.1. XM_001243545.1. XP_001249050.1. XM_001249049.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4562835. 4565258.
KEGG	cim:CIMG_02821. cim:CIMG_02987.
Phylogenomic databases
KO	K01580.
Family and domain databases
Gene3D	3.40.640.10. 1 hit.
InterPro	IPR010107. Glutamate_decarboxylase. IPR002129. PyrdxlP-dep_de-COase. IPR015424. PyrdxlP-dep_Trfase. IPR015421. PyrdxlP-dep_Trfase_major_sub1. [Graphical view]
PANTHER	PTHR11999:SF1. PTHR11999:SF1. 1 hit.
Pfam	PF00282. Pyridoxal_deC. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

J3KAC9_COCIM

Accession

Primary (citable) accession number: J3KAC9

Entry history

Integrated into UniProtKB/TrEMBL:	October 3, 2012
Last sequence update:	October 3, 2012
Last modified:	March 6, 2013
This is version 6 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)