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Protein

Glutamate decarboxylase

Gene

CIMG_10020

Organism
Coccidioides immitis (strain RS) (Valley fever fungus)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDecarboxylaseUniRule annotation, Lyase
LigandPyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
ORF Names:CIMG_10020Imported
OrganismiCoccidioides immitis (strain RS) (Valley fever fungus)Imported
Taxonomic identifieri246410 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesOnygenales incertae sedisCoccidioides
Proteomesi
  • UP000001261 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:CIMG_10020

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei302N6-(pyridoxal phosphate)lysineUniRule annotation1

Interactioni

Protein-protein interaction databases

STRINGi246410.XP_001238998.1

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG1238 Eukaryota
COG2303 LUCA
InParanoidiJ3K0N1
KOiK01580
OrthoDBiEOG092C132D

Family and domain databases

Gene3Di3.40.640.10, 1 hit
InterProiView protein in InterPro
IPR010107 Glutamate_decarboxylase
IPR002129 PyrdxlP-dep_de-COase
IPR015424 PyrdxlP-dep_Trfase
IPR015421 PyrdxlP-dep_Trfase_major
PANTHERiPTHR43321 PTHR43321, 1 hit
PfamiView protein in Pfam
PF00282 Pyridoxal_deC, 1 hit
SUPFAMiSSF53383 SSF53383, 2 hits
TIGRFAMsiTIGR01788 Glu-decarb-GAD, 1 hit

Sequencei

Sequence statusi: Complete.

J3K0N1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHLATHVNPE EVIEQLRNDP EESHRQHVFT LNAVATRTAY STRYASSEEI
60 70 80 90 100
PKFRIPQLGA SAEAVYRLLR DELDLDGIPN LNMASFVGTF MEREAQQLLV
110 120 130 140 150
ENIGKNLADA DEYPALMDLH ARCISMIANM WHPQPGEQPI GTATTGSSEA
160 170 180 190 200
IQLGGLAMKR RWQEKRRAEG KDTSKPNILM GANAQVALLK FARYFDVEAR
210 220 230 240 250
ILDVSENSHY RLDPNDIKKN VDENTIGIFV ILGSTYTGHY EPVEELSRIL
260 270 280 290 300
DQVQEEHGWD IPIHVDAASG GFIAPFTYAG AGGSKWDFEL PRVHSINVSG
310 320 330 340 350
HKFGLVYVGL GWIIWRDRAY LPKDLIFELH YLGGTEESFG LNFSRPGIQV
360 370 380 390 400
IGQYYNLIRL GFDGYREVME NCLRNARLLS KALERTGWYV CVSDIHRKKG
410 420 430 440 450
DYRFRGVGEI QPHRPGETSA DYNEGLPVVA FRFSEQFKKE YPDVKQEAIS
460 470 480 490 500
LLLRAKQYII PNYPLPPKTD NIEILRVVVR ESMSGDLIDK LISDIVEVTE
510 520 530 540 550
RVMTSEPIDV AVLQSRPTSL ARRHGRLETK LPAKKITKVK AGEKARHPMA

KGGHRSVC
Length:558
Mass (Da):63,021
Last modified:May 27, 2015 - v2
Checksum:i4C60356FE9BE0CBA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG704915 Genomic DNA Translation: EAS27415.3
RefSeqiXP_001238998.2, XM_001238997.2

Genome annotation databases

EnsemblFungiiEAS27415; EAS27415; CIMG_10020
GeneIDi4557991
KEGGicim:CIMG_10020

Similar proteinsi

Entry informationi

Entry nameiJ3K0N1_COCIM
AccessioniPrimary (citable) accession number: J3K0N1
Entry historyiIntegrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: May 27, 2015
Last modified: April 25, 2018
This is version 31 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health