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Protein

Glutamate decarboxylase

Gene

CIMG_10020

Organism
Coccidioides immitis (strain RS) (Valley fever fungus)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
ORF Names:CIMG_10020Imported
OrganismiCoccidioides immitis (strain RS) (Valley fever fungus)Imported
Taxonomic identifieri246410 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesOnygenales incertae sedisCoccidioides
Proteomesi
  • UP000001261 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:CIMG_10020.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei302N6-(pyridoxal phosphate)lysineUniRule annotation1

Interactioni

Protein-protein interaction databases

STRINGi246410.XP_001240060.1.

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG1238. Eukaryota.
COG2303. LUCA.
InParanoidiJ3K0N1.
KOiK01580.
OrthoDBiEOG092C132D.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 2 hits.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

J3K0N1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHLATHVNPE EVIEQLRNDP EESHRQHVFT LNAVATRTAY STRYASSEEI
60 70 80 90 100
PKFRIPQLGA SAEAVYRLLR DELDLDGIPN LNMASFVGTF MEREAQQLLV
110 120 130 140 150
ENIGKNLADA DEYPALMDLH ARCISMIANM WHPQPGEQPI GTATTGSSEA
160 170 180 190 200
IQLGGLAMKR RWQEKRRAEG KDTSKPNILM GANAQVALLK FARYFDVEAR
210 220 230 240 250
ILDVSENSHY RLDPNDIKKN VDENTIGIFV ILGSTYTGHY EPVEELSRIL
260 270 280 290 300
DQVQEEHGWD IPIHVDAASG GFIAPFTYAG AGGSKWDFEL PRVHSINVSG
310 320 330 340 350
HKFGLVYVGL GWIIWRDRAY LPKDLIFELH YLGGTEESFG LNFSRPGIQV
360 370 380 390 400
IGQYYNLIRL GFDGYREVME NCLRNARLLS KALERTGWYV CVSDIHRKKG
410 420 430 440 450
DYRFRGVGEI QPHRPGETSA DYNEGLPVVA FRFSEQFKKE YPDVKQEAIS
460 470 480 490 500
LLLRAKQYII PNYPLPPKTD NIEILRVVVR ESMSGDLIDK LISDIVEVTE
510 520 530 540 550
RVMTSEPIDV AVLQSRPTSL ARRHGRLETK LPAKKITKVK AGEKARHPMA

KGGHRSVC
Length:558
Mass (Da):63,021
Last modified:May 27, 2015 - v2
Checksum:i4C60356FE9BE0CBA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG704915 Genomic DNA. Translation: EAS27415.3.
RefSeqiXP_001238998.2. XM_001238997.2.

Genome annotation databases

EnsemblFungiiEAS27415; EAS27415; CIMG_10020.
GeneIDi4557991.
KEGGicim:CIMG_10020.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG704915 Genomic DNA. Translation: EAS27415.3.
RefSeqiXP_001238998.2. XM_001238997.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi246410.XP_001240060.1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiEAS27415; EAS27415; CIMG_10020.
GeneIDi4557991.
KEGGicim:CIMG_10020.

Organism-specific databases

EuPathDBiFungiDB:CIMG_10020.

Phylogenomic databases

eggNOGiKOG1238. Eukaryota.
COG2303. LUCA.
InParanoidiJ3K0N1.
KOiK01580.
OrthoDBiEOG092C132D.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 2 hits.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiJ3K0N1_COCIM
AccessioniPrimary (citable) accession number: J3K0N1
Entry historyi
Integrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: May 27, 2015
Last modified: November 30, 2016
This is version 20 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.