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Protein

Polyribonucleotide nucleotidyltransferase

Gene

pnp

Organism
Brevibacillus sp. CF112
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.UniRule annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi491MagnesiumUniRule annotation1
Metal bindingi497MagnesiumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferaseUniRule annotation, RNA-bindingUniRule annotation, Transferase
LigandMagnesiumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Polyribonucleotide nucleotidyltransferaseUniRule annotation (EC:2.7.7.8UniRule annotation)
Alternative name(s):
Polynucleotide phosphorylaseUniRule annotation
Short name:
PNPaseUniRule annotation
Gene namesi
Name:pnpUniRule annotation
ORF Names:PMI08_04889Imported
OrganismiBrevibacillus sp. CF112Imported
Taxonomic identifieri1144311 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesPaenibacillaceaeBrevibacillus
Proteomesi
  • UP000007279 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini627 – 695S1 motifInterPro annotationAdd BLAST69

Sequence similaritiesi

Belongs to the polyribonucleotide nucleotidyltransferase family.UniRule annotation

Phylogenomic databases

OrthoDBiPOG091H00M0

Family and domain databases

Gene3Di3.30.1370.10, 1 hit
3.30.230.70, 2 hits
HAMAPiMF_01595 PNPase, 1 hit
InterProiView protein in InterPro
IPR001247 ExoRNase_PH_dom1
IPR015847 ExoRNase_PH_dom2
IPR036345 ExoRNase_PH_dom2_sf
IPR004087 KH_dom
IPR004088 KH_dom_type_1
IPR036612 KH_dom_type_1_sf
IPR012340 NA-bd_OB-fold
IPR012162 PNPase
IPR027408 PNPase/RNase_PH_dom_sf
IPR015848 PNPase_PH_RNA-bd_bac/org-type
IPR020568 Ribosomal_S5_D2-typ_fold
IPR022967 S1_dom
IPR003029 S1_domain
PANTHERiPTHR11252 PTHR11252, 1 hit
PfamiView protein in Pfam
PF00013 KH_1, 1 hit
PF03726 PNPase, 1 hit
PF01138 RNase_PH, 2 hits
PF03725 RNase_PH_C, 2 hits
PF00575 S1, 1 hit
PIRSFiPIRSF005499 PNPase, 1 hit
SMARTiView protein in SMART
SM00322 KH, 1 hit
SM00316 S1, 1 hit
SUPFAMiSSF50249 SSF50249, 1 hit
SSF54211 SSF54211, 2 hits
SSF54791 SSF54791, 1 hit
SSF55666 SSF55666, 2 hits
TIGRFAMsiTIGR03591 polynuc_phos, 1 hit
PROSITEiView protein in PROSITE
PS50126 S1, 1 hit

Sequencei

Sequence statusi: Complete.

J2QGQ4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEQQYRTYDF ELAGRKLTLE FGKMAKQANG SVLVRYGDTA ILSAVTVSKE
60 70 80 90 100
PKALDFFPLT VNYEERLYAV GKIPGGFIKR EGRPSEKAIL ASRLIDRPIR
110 120 130 140 150
PLFAEGFRND VQIVNTVLSV DQDCSPEIAA MIGTSAALCV SEIPFEGPIA
160 170 180 190 200
GVIVGRIDGE FIINPTVEQA EKSDIHLVVA GTHKAINMVE AAANQVPESV
210 220 230 240 250
MLEAIMAGHE VIKQLVEFQN QIVAEIGKEK MEVILHEVDP EIDQAVREFA
260 270 280 290 300
EARLKEAVRI EEKQARYDAI DNIKEETKEH FAAKDPEAYP EQEKMISEVL
310 320 330 340 350
GNIVKDEVRR LITEEKVRPD GRALNEIRPL SSETGILSRT HGSAMFTRGQ
360 370 380 390 400
TQALSVCTLG ALGDVQILDG LGLEESKRFM HHYNFPPYSV GEARPLRPPG
410 420 430 440 450
RREIGHGALG ERAIEPIIPS EHEFPYTIRL VSEVIESNGS TSQASICASV
460 470 480 490 500
LALMDAGVPI KAPVAGIAMG LIMSKDEQSF SILTDIQGME DHLGDMDFKV
510 520 530 540 550
AGTEAGVTAI QMDIKISGIN REILQQALEQ AREGRLHILK HMMSTISEPR
560 570 580 590 600
KELSPYAPKI LTMTINPDKI RDVIGPQGRV INKIIEETGV KIDIEQDGRV
610 620 630 640 650
FIASINHEAN MRAKQIIEDL VREVAVGQIY LGTVKRVEKY GAFIELFAGK
660 670 680 690 700
EGLCHISQLA EERVAKTEDV VAIGDKVQVK VTEIDDQGRI NLSRKAVLKE
710
QAAAAQADKA PTQAE
Length:715
Mass (Da):78,725
Last modified:October 3, 2012 - v1
Checksum:iB2B73153A307F962
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AKKB01000151 Genomic DNA Translation: EJL39377.1
RefSeqiWP_007786846.1, NZ_AKKB01000151.1

Genome annotation databases

EnsemblBacteriaiEJL39377; EJL39377; PMI08_04889
PATRICifig|1144311.3.peg.4896

Similar proteinsi

Entry informationi

Entry nameiJ2QGQ4_9BACL
AccessioniPrimary (citable) accession number: J2QGQ4
Entry historyiIntegrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: May 23, 2018
This is version 42 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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