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Protein
Submitted name:

Eukaryotic translation initiation factor 1A

Gene

TTHERM_00497990

Organism
Tetrahymena thermophila (strain SB210)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionInitiation factorPROSITE-ProRule annotationImported
Biological processProtein biosynthesis

Names & Taxonomyi

Protein namesi
Submitted name:
Eukaryotic translation initiation factor 1AImported
Gene namesi
ORF Names:TTHERM_00497990Imported
OrganismiTetrahymena thermophila (strain SB210)Imported
Taxonomic identifieri312017 [NCBI]
Taxonomic lineageiEukaryotaAlveolataCiliophoraIntramacronucleataOligohymenophoreaHymenostomatidaTetrahymeninaTetrahymenidaeTetrahymena
Proteomesi
  • UP000009168 Componenti: Unassembled WGS sequence

Interactioni

Protein-protein interaction databases

STRINGi5911.EAS07745.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4BTSX-ray3.70A0/B0/C0/D02-193[»]
DisProtiDP00914.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini21 – 95S1-likeInterPro annotationAdd BLAST75

Sequence similaritiesi

Belongs to the eIF-1A family.UniRule annotation

Phylogenomic databases

InParanoidiI7MK25.
KOiK03236.
OMAiDADIVHK.

Family and domain databases

CDDicd05793. S1_IF1A. 1 hit.
HAMAPiMF_00216. aIF_1A. 1 hit.
InterProiView protein in InterPro
IPR012340. NA-bd_OB-fold.
IPR006196. RNA-binding_domain_S1_IF1.
IPR001253. TIF_eIF-1A.
IPR018104. TIF_eIF-1A_CS.
PANTHERiPTHR21668. PTHR21668. 1 hit.
PfamiView protein in Pfam
PF01176. eIF-1a. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD005579. TIF_eIF-1A. 1 hit.
SMARTiView protein in SMART
SM00652. eIF1a. 1 hit.
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00523. eIF-1A. 1 hit.
PROSITEiView protein in PROSITE
PS01262. IF1A. 1 hit.
PS50832. S1_IF1_TYPE. 1 hit.

Sequencei

Sequence statusi: Complete.

I7MK25-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPKNKGRGGK NYRRGKNENE TKRELVFKEE GMEYAQVIKM LGNGRLEVFC
60 70 80 90 100
FDGKRRIGHI CGRLKKKVWI SMDDIVLVGL RDFQDDKCDI LLKYLPDEVR
110 120 130 140 150
NLKQYGEIDE NIKINDKSGA DQADVVFEDS DSDDKDDDDD DEDEQPTRQT
160 170 180 190
NTRVNQMVES SDEEDNKETG NYEEQKYDQK HQNKKDDIDI DDI
Length:193
Mass (Da):22,550
Last modified:October 3, 2012 - v1
Checksum:iDDD89D7A6FF2C018
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG662212 Genomic DNA. Translation: EAS07745.3.
RefSeqiXP_001027987.3. XM_001027987.3.
UniGeneiTth.5318.

Genome annotation databases

EnsemblProtistsiEAS07745; EAS07745; TTHERM_00497990.
GeneIDi7835355.
KEGGitet:TTHERM_00497990.

Entry informationi

Entry nameiI7MK25_TETTS
AccessioniPrimary (citable) accession number: I7MK25
Entry historyiIntegrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: September 27, 2017
This is version 30 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported