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I7MGI2

- I7MGI2_TETTS

UniProt

I7MGI2 - I7MGI2_TETTS

Protein

Elongation factor Tu

Gene

TTHERM_00151810

Organism
Tetrahymena thermophila (strain SB210)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 12 (01 Oct 2014)
      Sequence version 2 (16 Apr 2014)
      Previous versions | rss
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    Functioni

    This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: InterPro
    2. GTP binding Source: UniProtKB-KW
    3. translation elongation factor activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Elongation factorUniRule annotationImported

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor TuUniRule annotation
    Gene namesi
    ORF Names:TTHERM_00151810Imported
    OrganismiTetrahymena thermophila (strain SB210)Imported
    Taxonomic identifieri312017 [NCBI]
    Taxonomic lineageiEukaryotaAlveolataCiliophoraIntramacronucleataOligohymenophoreaHymenostomatidaTetrahymeninaTetrahymenidaeTetrahymena
    ProteomesiUP000009168: Unassembled WGS sequence

    Subcellular locationi

    GO - Cellular componenti

    1. intracellular Source: InterPro

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS00301. EFACTOR_GTP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    I7MGI2-1 [UniParc]FASTAAdd to Basket

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    MFKNILKLGS NTQKTLSAIP CYGFAKFQRN KPHLNVGTIG HIDHGKTTLT    50
    AAITKICADK KLAEFMAYDS IDKAPEEKAR GITINTATVE YETETRHYGH 100
    VDCPGHIDYV KNMITGAAKM DAGILVCSAT DGVMPQTREH ILLCRQVGVK 150
    TIIVFVNKCD MAKDPEIQEL VEMEVRELLS KYEYNGDEAP VIFGSALCAL 200
    NGTDPEIGIN KINTLLDTMD KQIALPERTV DKPFMMSVEG TYQIPGRGTV 250
    VTGTVDTGKV KTGEDIEIVG YSNKVLKTTI TGIETFRKQL DYAEAGDNVG 300
    LLLRGVTRDD VRRGQVLSKP GTQESHKKIE ANLYILTEQE GGRKKPFPDG 350
    YRPQLYLRTA DVAAQISIHG ANKLGMPGDN ITANLDLHFP LPVAPGKLTI 400
    ILFNNQCQQQ NNFQIKGLRF ALREGGKTIA AGVISKVIPE EKEAPKK 447
    Length:447
    Mass (Da):49,103
    Last modified:April 16, 2014 - v2
    Checksum:i4DAEB33C1CE5BDA1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    GG662603 Genomic DNA. Translation: EAS01468.2.
    UniGeneiTth.2076.

    Genome annotation databases

    EnsemblProtistsiEAS01468; EAS01468; TTHERM_00151810.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    GG662603 Genomic DNA. Translation: EAS01468.2 .
    UniGenei Tth.2076.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblProtistsi EAS01468 ; EAS01468 ; TTHERM_00151810 .

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS00301. EFACTOR_GTP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a model eukaryote."
      Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R., Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L., Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M., Carlton J.M.
      , Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L., Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y., Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z., Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A., Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A., Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A., Hamilton E.P., Orias E.
      PLoS Biol. 4:1620-1642(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SB210Imported.

    Entry informationi

    Entry nameiI7MGI2_TETTS
    AccessioniPrimary (citable) accession number: I7MGI2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 3, 2012
    Last sequence update: April 16, 2014
    Last modified: October 1, 2014
    This is version 12 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3