I7M6X2 (I7M6X2_TETTS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Superoxide dismutase [Cu-Zn] RuleBase RU000393
EC=1.15.1.1 RuleBase RU000393

Gene names

ORF Names:

TTHERM_00059350 EMBL EAR87422.1

Organism

Tetrahymena thermophila (strain SB210) [Reference proteome] EMBL EAR87422.1

Taxonomic identifier

312017 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Alveolata › Ciliophora › Intramacronucleata › Oligohymenophorea › Hymenostomatida › Tetrahymenina › Tetrahymenidae › Tetrahymena › Tetrahymena thermophila

Protein attributes

Sequence length	196 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Destroys radicals which are normally produced within the cells and which are toxic to biological systems By similarity. RuleBase RU000393
Catalytic activity	2 superoxide + 2 H+ = O2 + H2O2. RuleBase RU000393
Cofactor	Binds 1 copper ion per subunit By similarity. RuleBase RU000393 Binds 1 zinc ion per subunit By similarity. RuleBase RU000393
Sequence similarities	Belongs to the Cu-Zn superoxide dismutase family. RuleBase RU000393

Ontologies

Keywords
Ligand	Copper RuleBase RU000393 Metal-binding RuleBase RU000393 Zinc RuleBase RU000393
Molecular function	Oxidoreductase RuleBase RU000393
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	superoxide metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW superoxide dismutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	I7M6X2 [UniParc]. Last modified October 3, 2012. Version 1. Checksum: 32660318BED0B43D	FASTA	196	21,355
	10 20 30 40 50 60 MLVKSVLLGA AGTALFSYSN QKTYKAEKNA GERIAIAILY PAPGYDVTGA VTFYQKDLHS 70 80 90 100 110 120 KTQITARLKN LNPNGLFGFH IHEFGDLTNG TESVGPHYNP FNKKHGSPRE DESHMGDLGN 130 140 150 160 170 180 IKADDLGYGY YTSENNKVTL FGEYSVVGRS VLVNKNEDDL GRGNHPDSHT NGHSGPRIAA 190 GIIGLAYELK NLPARF

References

[1]

"Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a model eukaryote." Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R., Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L., Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M., Carlton J.M. , Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L., Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y., Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z., Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A., Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A., Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A., Hamilton E.P., Orias E. PLoS Biol. 4:1620-1642(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SB210.

Cross-references

Sequence databases
EMBL GenBank DDBJ	GG662853 Genomic DNA. Translation: EAR87422.1.
RefSeq	XP_001007667.1. XM_001007667.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7841888.
KEGG	tet:TTHERM_00059350.
Phylogenomic databases
KO	K04565.
Family and domain databases
Gene3D	2.60.40.200. 1 hit.
InterPro	IPR024134. SOD_Cu/Zn_/chaperones. IPR018152. SOD_Cu/Zn_BS. IPR001424. SOD_Cu_Zn_dom. [Graphical view]
PANTHER	PTHR10003. PTHR10003. 1 hit.
Pfam	PF00080. Sod_Cu. 1 hit. [Graphical view]
PRINTS	PR00068. CUZNDISMTASE.
SUPFAM	SSF49329. SOD_Cu_Zn. 1 hit.
PROSITE	PS00087. SOD_CU_ZN_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

I7M6X2_TETTS

Accession

Primary (citable) accession number: I7M6X2

Entry history

Integrated into UniProtKB/TrEMBL:	October 3, 2012
Last sequence update:	October 3, 2012
Last modified:	March 6, 2013
This is version 5 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)