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I7M6X2

- I7M6X2_TETTS

UniProt

I7M6X2 - I7M6X2_TETTS

Protein

Superoxide dismutase [Cu-Zn]

Gene

TTHERM_00059350

Organism
Tetrahymena thermophila (strain SB210)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 13 (01 Oct 2014)
      Sequence version 2 (16 Apr 2014)
      Previous versions | rss
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    Functioni

    Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

    Catalytic activityi

    2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

    Cofactori

    Binds 1 copper ion per subunit.UniRule annotation
    Binds 1 zinc ion per subunit.UniRule annotation

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. superoxide dismutase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    OxidoreductaseUniRule annotation

    Keywords - Ligandi

    CopperUniRule annotation, Metal-bindingUniRule annotation, ZincUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Superoxide dismutase [Cu-Zn]UniRule annotation (EC:1.15.1.1UniRule annotation)
    Gene namesi
    ORF Names:TTHERM_00059350Imported
    OrganismiTetrahymena thermophila (strain SB210)Imported
    Taxonomic identifieri312017 [NCBI]
    Taxonomic lineageiEukaryotaAlveolataCiliophoraIntramacronucleataOligohymenophoreaHymenostomatidaTetrahymeninaTetrahymenidaeTetrahymena
    ProteomesiUP000009168: Unassembled WGS sequence

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the Cu-Zn superoxide dismutase family.UniRule annotation

    Family and domain databases

    Gene3Di2.60.40.200. 1 hit.
    InterProiIPR018152. SOD_Cu/Zn_BS.
    IPR001424. SOD_Cu_Zn_dom.
    [Graphical view]
    PfamiPF00080. Sod_Cu. 1 hit.
    [Graphical view]
    PRINTSiPR00068. CUZNDISMTASE.
    SUPFAMiSSF49329. SSF49329. 1 hit.
    PROSITEiPS00087. SOD_CU_ZN_1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    I7M6X2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLTLLSKFIQ TKSDIYLEQI FNFLVTKFYI KISQKILLKI ARQIQTNKQT    50
    NLSKKHILKS RMLVKSVLLG AAGTALFSYS NQKTYKAEKN AGERIAIAIL 100
    YPAPGYDVTG AVTFYQKDLH SKTQITARLK NLNPNGLFGF HIHEFGDLTN 150
    GTESVGPHYN PFNKKHGSPR EDESHMGDLG NIKADDLGYG YYTSENNKVT 200
    LFGEYSVVGR SVLVNKNEDD LGRGNHPDSH TNGHSGPRIA AGIIGLAYEL 250
    KNLPARF 257
    Length:257
    Mass (Da):28,636
    Last modified:April 16, 2014 - v2
    Checksum:iD5C9C001F16A3D14
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    GG662853 Genomic DNA. Translation: EAR87422.2.

    Genome annotation databases

    EnsemblProtistsiEAR87422; EAR87422; TTHERM_00059350.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    GG662853 Genomic DNA. Translation: EAR87422.2 .

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblProtistsi EAR87422 ; EAR87422 ; TTHERM_00059350 .

    Family and domain databases

    Gene3Di 2.60.40.200. 1 hit.
    InterProi IPR018152. SOD_Cu/Zn_BS.
    IPR001424. SOD_Cu_Zn_dom.
    [Graphical view ]
    Pfami PF00080. Sod_Cu. 1 hit.
    [Graphical view ]
    PRINTSi PR00068. CUZNDISMTASE.
    SUPFAMi SSF49329. SSF49329. 1 hit.
    PROSITEi PS00087. SOD_CU_ZN_1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a model eukaryote."
      Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R., Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L., Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M., Carlton J.M.
      , Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L., Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y., Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z., Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A., Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A., Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A., Hamilton E.P., Orias E.
      PLoS Biol. 4:1620-1642(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SB210Imported.

    Entry informationi

    Entry nameiI7M6X2_TETTS
    AccessioniPrimary (citable) accession number: I7M6X2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 3, 2012
    Last sequence update: April 16, 2014
    Last modified: October 1, 2014
    This is version 13 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3