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I7JAC0

- I7JAC0_9RICK

UniProt

I7JAC0 - I7JAC0_9RICK

Protein

Elongation factor Tu

Gene

tuf

Organism
Wolbachia endosymbiont of Onchocerca ochengi
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 14 (01 Oct 2014)
      Sequence version 1 (03 Oct 2012)
      Previous versions | rss
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    Functioni

    This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi19 – 268GTPUniRule annotation
    Nucleotide bindingi76 – 805GTPUniRule annotation
    Nucleotide bindingi131 – 1344GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: InterPro
    2. GTP binding Source: UniProtKB-HAMAP
    3. translation elongation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Elongation factorUniRule annotationImported

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciWEND100901:GLMP-129-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor TuUniRule annotation
    Short name:
    EF-TuUniRule annotation
    Gene namesi
    Name:tufUniRule annotation
    ORF Names:wOo_01560Imported
    OrganismiWolbachia endosymbiont of Onchocerca ochengiImported
    Taxonomic identifieri100901 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesAnaplasmataceaeWolbachieaeWolbachia
    ProteomesiUP000007516: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.UniRule annotation
    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

    Phylogenomic databases

    KOiK02358.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00118_B. EF_Tu_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS00301. EFACTOR_GTP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    I7JAC0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAQIVEAFGK PHVNVGTIGH VDHGKTTLTA AITKYYGNFV AYDQIDKAPE    50
    ERKRGITIAT AHVEYETDKK HYAHVDCPGH ADYVKNMIVG AAQMDAAILV 100
    VSGVDGPMPQ TREHILLAKQ VGVKYIVVYI NKADVADHDI IGLVEMEVRE 150
    LLSKYEFPGD DVPVVIGSAL KALESEDSEY GKRSIEKLME KLDEYVAVPP 200
    RPVDLPFLMP IEDVFSILGR GTVVTGRIER GEIRTGEEME IVGLKATRKA 250
    ICTGVEMFKK SLDKGCAGLN VGVLLRGTKR EEVERGQVLA KPNSITPHKK 300
    FKAEVYILKQ EEGGRHTPFF ENYQPQFYIR TTDVTGSIKL LKGKEMVMPG 350
    DNVSIEVELQ VPIAMDKGLR FAIREGGRTV GSGVVSEILE 390
    Length:390
    Mass (Da):43,034
    Last modified:October 3, 2012 - v1
    Checksum:iB97F6D85A242D60B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    HE660029 Genomic DNA. Translation: CCF77983.1.
    RefSeqiWP_014868768.1. NC_018267.1.
    YP_006555800.1. NC_018267.1.

    Genome annotation databases

    EnsemblBacteriaiCCF77983; CCF77983; wOo_01560.
    GeneIDi13415429.
    KEGGiwoo:wOo_01560.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    HE660029 Genomic DNA. Translation: CCF77983.1 .
    RefSeqi WP_014868768.1. NC_018267.1.
    YP_006555800.1. NC_018267.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CCF77983 ; CCF77983 ; wOo_01560 .
    GeneIDi 13415429.
    KEGGi woo:wOo_01560.

    Phylogenomic databases

    KOi K02358.

    Enzyme and pathway databases

    BioCyci WEND100901:GLMP-129-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00118_B. EF_Tu_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS00301. EFACTOR_GTP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Analysis of gene expression from the Wolbachia genome of a filarial nematode supports both metabolic and defensive roles within the symbiosis."
      Darby A.C., Armstrong S.D., Bah G.S., Kaur G., Hughes M.A., Kay S.M., Koldkaer P., Rainbow L., Radford A.D., Blaxter M.L., Tanya V.N., Trees A.J., Cordaux R., Wastling J.M., Makepeace B.L.
      Genome Res. 22:2467-2477(2012)
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: WOoImported.

    Entry informationi

    Entry nameiI7JAC0_9RICK
    AccessioniPrimary (citable) accession number: I7JAC0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 3, 2012
    Last sequence update: October 3, 2012
    Last modified: October 1, 2014
    This is version 14 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3