I7JAC0 (I7JAC0_9RICK) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Elongation factor Tu HAMAP-Rule MF_00118
Short name=EF-Tu HAMAP-Rule MF_00118

Gene names

Name:	tuf HAMAP-Rule MF_00118
ORF Names:	wOo_01560 EMBL CCF77983.1

Organism

Wolbachia endosymbiont of Onchocerca ochengi EMBL CCF77983.1

Taxonomic identifier

100901 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Anaplasmataceae › Wolbachieae › Wolbachia

Protein attributes

Sequence length	390 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity. RuleBase RU000325 HAMAP-Rule MF_00118
Subunit structure	Monomer By similarity. HAMAP-Rule MF_00118
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00118.
Sequence similarities	Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily. RuleBase RU000325 HAMAP-Rule MF_00118

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm HAMAP-Rule MF_00118
Ligand	GTP-binding RuleBase RU000323 HAMAP-Rule MF_00118 Nucleotide-binding
Molecular function	Elongation factor RuleBase RU000325 HAMAP-Rule MF_00118 EMBL CCF77983.1
Gene Ontology (GO)
Biological_process	GTP catabolic process Inferred from electronic annotation. Source: GOC
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	GTP binding Inferred from electronic annotation. Source: HAMAP GTPase activity Inferred from electronic annotation. Source: InterPro translation elongation factor activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	19 – 26	8	GTP By similarity HAMAP-Rule MF_00118
	Nucleotide binding	76 – 80	5	GTP By similarity HAMAP-Rule MF_00118
	Nucleotide binding	131 – 134	4	GTP By similarity HAMAP-Rule MF_00118

Sequences

	Sequence		Length	Mass (Da)
	I7JAC0 [UniParc]. Last modified October 3, 2012. Version 1. Checksum: B97F6D85A242D60B	FASTA	390	43,034
	10 20 30 40 50 60 MAQIVEAFGK PHVNVGTIGH VDHGKTTLTA AITKYYGNFV AYDQIDKAPE ERKRGITIAT 70 80 90 100 110 120 AHVEYETDKK HYAHVDCPGH ADYVKNMIVG AAQMDAAILV VSGVDGPMPQ TREHILLAKQ 130 140 150 160 170 180 VGVKYIVVYI NKADVADHDI IGLVEMEVRE LLSKYEFPGD DVPVVIGSAL KALESEDSEY 190 200 210 220 230 240 GKRSIEKLME KLDEYVAVPP RPVDLPFLMP IEDVFSILGR GTVVTGRIER GEIRTGEEME 250 260 270 280 290 300 IVGLKATRKA ICTGVEMFKK SLDKGCAGLN VGVLLRGTKR EEVERGQVLA KPNSITPHKK 310 320 330 340 350 360 FKAEVYILKQ EEGGRHTPFF ENYQPQFYIR TTDVTGSIKL LKGKEMVMPG DNVSIEVELQ 370 380 390 VPIAMDKGLR FAIREGGRTV GSGVVSEILE

References

[1]

"Analysis of gene expression from the Wolbachia genome of a filarial nematode supports both metabolic and defensive roles within the symbiosis." Darby A.C., Armstrong S.D., Bah G.S., Kaur G., Hughes M.A., Kay S.M., Koldkaer P., Rainbow L., Radford A.D., Blaxter M.L., Tanya V.N., Trees A.J., Cordaux R., Wastling J.M., Makepeace B.L. Genome Res. 22:2467-2477(2012) Cited for: NUCLEOTIDE SEQUENCE. Strain: WOo EMBL CCF77983.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	HE660029 Genomic DNA. Translation: CCF77983.1.
RefSeq	YP_006555800.1. NC_018267.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CCF77983; CCF77983; wOo_01560.
GeneID	13415429.
KEGG	woo:wOo_01560.
Phylogenomic databases
KO	K02358.
Family and domain databases
HAMAP	MF_00118_B. EF_Tu_B.
InterPro	IPR000795. EF_GTP-bd_dom. IPR005225. Small_GTP-bd_dom. IPR009001. Transl_elong_EF1A/Init_IF2_C. IPR004161. Transl_elong_EFTu/EF1A_2. IPR004541. Transl_elong_EFTu/EF1A_bac/org. IPR004160. Transl_elong_EFTu/EF1A_C. IPR009000. Transl_elong_init/rib_B-barrel. [Graphical view]
Pfam	PF00009. GTP_EFTU. 1 hit. PF03144. GTP_EFTU_D2. 1 hit. PF03143. GTP_EFTU_D3. 1 hit. [Graphical view]
PRINTS	PR00315. ELONGATNFCT.
SUPFAM	SSF50465. Elong_init_C. 1 hit. SSF50447. Translat_factor. 1 hit.
TIGRFAMs	TIGR00485. EF-Tu. 1 hit. TIGR00231. small_GTP. 1 hit.
PROSITE	PS00301. EFACTOR_GTP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

I7JAC0_9RICK

Accession

Primary (citable) accession number: I7JAC0

Entry history

Integrated into UniProtKB/TrEMBL:	October 3, 2012
Last sequence update:	October 3, 2012
Last modified:	April 3, 2013
This is version 6 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)