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I7JAC0

- I7JAC0_9RICK

UniProt

I7JAC0 - I7JAC0_9RICK

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Protein

Elongation factor Tu

Gene

tuf

Organism
Wolbachia endosymbiont of Onchocerca ochengi
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 268GTPUniRule annotation
Nucleotide bindingi76 – 805GTPUniRule annotation
Nucleotide bindingi131 – 1344GTPUniRule annotation

GO - Molecular functioni

  1. GTPase activity Source: InterPro
  2. GTP binding Source: UniProtKB-HAMAP
  3. translation elongation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Elongation factorUniRule annotation

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciWEND100901:GLMP-129-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tufUniRule annotation
ORF Names:wOo_01560Imported
OrganismiWolbachia endosymbiont of Onchocerca ochengiImported
Taxonomic identifieri100901 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesAnaplasmataceaeWolbachieaeWolbachia
ProteomesiUP000007516: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

KOiK02358.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

I7JAC0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAQIVEAFGK PHVNVGTIGH VDHGKTTLTA AITKYYGNFV AYDQIDKAPE
60 70 80 90 100
ERKRGITIAT AHVEYETDKK HYAHVDCPGH ADYVKNMIVG AAQMDAAILV
110 120 130 140 150
VSGVDGPMPQ TREHILLAKQ VGVKYIVVYI NKADVADHDI IGLVEMEVRE
160 170 180 190 200
LLSKYEFPGD DVPVVIGSAL KALESEDSEY GKRSIEKLME KLDEYVAVPP
210 220 230 240 250
RPVDLPFLMP IEDVFSILGR GTVVTGRIER GEIRTGEEME IVGLKATRKA
260 270 280 290 300
ICTGVEMFKK SLDKGCAGLN VGVLLRGTKR EEVERGQVLA KPNSITPHKK
310 320 330 340 350
FKAEVYILKQ EEGGRHTPFF ENYQPQFYIR TTDVTGSIKL LKGKEMVMPG
360 370 380 390
DNVSIEVELQ VPIAMDKGLR FAIREGGRTV GSGVVSEILE
Length:390
Mass (Da):43,034
Last modified:October 3, 2012 - v1
Checksum:iB97F6D85A242D60B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE660029 Genomic DNA. Translation: CCF77983.1.
RefSeqiWP_014868768.1. NC_018267.1.
YP_006555800.1. NC_018267.1.

Genome annotation databases

EnsemblBacteriaiCCF77983; CCF77983; wOo_01560.
GeneIDi13415429.
KEGGiwoo:wOo_01560.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE660029 Genomic DNA. Translation: CCF77983.1 .
RefSeqi WP_014868768.1. NC_018267.1.
YP_006555800.1. NC_018267.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CCF77983 ; CCF77983 ; wOo_01560 .
GeneIDi 13415429.
KEGGi woo:wOo_01560.

Phylogenomic databases

KOi K02358.

Enzyme and pathway databases

BioCyci WEND100901:GLMP-129-MONOMER.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
HAMAPi MF_00118_B. EF_Tu_B.
InterProi IPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view ]
Pfami PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view ]
PRINTSi PR00315. ELONGATNFCT.
SUPFAMi SSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEi PS00301. EFACTOR_GTP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Analysis of gene expression from the Wolbachia genome of a filarial nematode supports both metabolic and defensive roles within the symbiosis."
    Darby A.C., Armstrong S.D., Bah G.S., Kaur G., Hughes M.A., Kay S.M., Koldkaer P., Rainbow L., Radford A.D., Blaxter M.L., Tanya V.N., Trees A.J., Cordaux R., Wastling J.M., Makepeace B.L.
    Genome Res. 22:2467-2477(2012)
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: WOoImported.

Entry informationi

Entry nameiI7JAC0_9RICK
AccessioniPrimary (citable) accession number: I7JAC0
Entry historyi
Integrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: October 29, 2014
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3