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Protein

Glycerol-3-phosphate dehydrogenase

Gene

glpD2

Organism
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.UniRule annotation

Cofactori

FADUniRule annotation

GO - Molecular functioni

  1. sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity Source: UniProtKB-EC

GO - Biological processi

  1. glycerol-3-phosphate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationSAAS annotation

Keywords - Ligandi

FlavoproteinUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenaseUniRule annotation (EC:1.1.5.3UniRule annotation)
Gene namesi
Name:glpD2Imported
Ordered Locus Names:MSMEI_6578Imported
ORF Names:LJ00_33400Imported
OrganismiMycobacterium smegmatis (strain ATCC 700084 / mc(2)155)Imported
Taxonomic identifieri246196 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
ProteomesiUP000006158: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. glycerol-3-phosphate dehydrogenase complex Source: InterPro
Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliI7GGN8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotation

Family and domain databases

InterProiIPR006076. FAD-dep_OxRdtase.
IPR000447. G3P_DH_FAD-dep.
[Graphical view]
PfamiPF01266. DAO. 1 hit.
[Graphical view]
PRINTSiPR01001. FADG3PDH.
PROSITEiPS00977. FAD_G3PDH_1. 1 hit.
PS00978. FAD_G3PDH_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

I7GGN8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGAYPLSPAH RAAALDRLAS DEFDVLVVGG GVVGAGAALD AATRGLRVGL
60 70 80 90 100
VEARDYASGT SSRSSKLFHG GLRYLEQFNF SLVFEALRER SLVLNTLCPH
110 120 130 140 150
LARPVPFIYP LQTRFDRAYA GLGIGVYDVM GAGRGVPGHH EHLGRARTLE
160 170 180 190 200
SFPSGSPAIR GAIRFYEGQV DDARHTMMLV RTAAHFGAVC ANSTRVTGFV
210 220 230 240 250
RDGERVAGVG VRDLDGGREF EVRAKQVINA TGVWTDETQG MAGGQGQFRV
260 270 280 290 300
RASKGVHLVV PRSRINSSTG IITRTEKSLL FVIPWGSHWI VGTTDTDWSL
310 320 330 340 350
DLAHPAASRA DIEYLLGHVN TLLADPLTAD DVVGVYAGLR PLLAGESDST
360 370 380 390 400
SKLSREHAVA SPVPGLTVIA GGKYTTYRVM AKDAVDLAVR GLGRAVPSSC
410 420 430 440 450
TERVPLLGAD GYPAAWNARR RTAEDTGLAV TTVAHLLGRY GTLTDELLEI
460 470 480 490 500
IAHRPDLGVP LAGAPEYLKV EAYYAASHEG ARHLEDVLTR RTRISIEVAD
510 520 530 540 550
RGVAAAREVA DLIAPVLGWS QTDIAREIEH YDARVAAERE SQHQLDDYTA
560
DAARLGAPDV RVGVTQ
Length:566
Mass (Da):60,686
Last modified:October 3, 2012 - v1
Checksum:iD659F842CACA8E3E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001663 Genomic DNA. Translation: AFP43004.1.
CP009494 Genomic DNA. Translation: AIU11725.1.
RefSeqiYP_006571299.1. NC_018289.1.

Genome annotation databases

EnsemblBacteriaiAFP43004; AFP43004; MSMEI_6578.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001663 Genomic DNA. Translation: AFP43004.1.
CP009494 Genomic DNA. Translation: AIU11725.1.
RefSeqiYP_006571299.1. NC_018289.1.

3D structure databases

ProteinModelPortaliI7GGN8.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFP43004; AFP43004; MSMEI_6578.

Family and domain databases

InterProiIPR006076. FAD-dep_OxRdtase.
IPR000447. G3P_DH_FAD-dep.
[Graphical view]
PfamiPF01266. DAO. 1 hit.
[Graphical view]
PRINTSiPR01001. FADG3PDH.
PROSITEiPS00977. FAD_G3PDH_1. 1 hit.
PS00978. FAD_G3PDH_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MC2 155Imported.
  2. "Interrupted coding sequences in Mycobacterium smegmatis: authentic mutations or sequencing errors?"
    Deshayes C., Perrodou E., Gallien S., Euphrasie D., Schaeffer C., Van-Dorsselaer A., Poch O., Lecompte O., Reyrat J.-M.
    Genome Biol. 8:R20.1-R20.9(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700084 / mc(2)155Imported and MC2 155Imported.
  3. "Ortho-proteogenomics: multiple proteomes investigation through orthology and a new MS-based protocol."
    Gallien S., Perrodou E., Carapito C., Deshayes C., Reyrat J.-M., Van Dorsselaer A., Poch O., Schaeffer C., Lecompte O.
    Genome Res. 19:128-135(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700084 / mc(2)155 and MC2 155.
  4. "Complete Genome Sequence of Mycobacterium smegmatis Laboratory Strains (INHwt) and Isoniazid Resistant (INHR1/R2) Mutant Strains."
    Mohan A., Padiadpu J., Baloni P., Chandra N.
    Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MC2 155Imported.

Entry informationi

Entry nameiI7GGN8_MYCS2
AccessioniPrimary (citable) accession number: I7GGN8
Entry historyi
Integrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: January 7, 2015
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.