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I7G5Y1

- I7G5Y1_MYCS2

UniProt

I7G5Y1 - I7G5Y1_MYCS2

Protein

Glutamate decarboxylase

Gene

gadB

Organism
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 12 (01 Oct 2014)
      Sequence version 1 (03 Oct 2012)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotation

    GO - Molecular functioni

    1. glutamate decarboxylase activity Source: UniProtKB-EC
    2. pyridoxal phosphate binding Source: InterPro

    GO - Biological processi

    1. glutamate metabolic process Source: InterPro

    Keywords - Molecular functioni

    DecarboxylaseUniRule annotation, Lyase

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
    Gene namesi
    Name:gadBImported
    Ordered Locus Names:MSMEI_1536Imported
    OrganismiMycobacterium smegmatis (strain ATCC 700084 / mc(2)155)Imported
    Taxonomic identifieri246196 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
    ProteomesiUP000006158: Chromosome

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the group II decarboxylase family.UniRule annotation

    Phylogenomic databases

    KOiK01580.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    InterProiIPR010107. Glutamate_decarboxylase.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view]
    PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
    PfamiPF00282. Pyridoxal_deC. 1 hit.
    [Graphical view]
    SUPFAMiSSF53383. SSF53383. 1 hit.
    TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    I7G5Y1-1 [UniParc]FASTAAdd to Basket

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    MSTSKGNFMS HKQSRGPHVA PAYTGRLAMA PVPSLRLPDE AMDPSAAYRF    50
    IHDELMLDGS SRLNLATFVT TWMDPEAEKL MAETFDKNMI DKDEYPATAA 100
    IEARCVSMVA DLFHAEDLRD DDPASAVGVS TIGSSEAVML AGLAMKWRWR 150
    AKAGDWKGRT PNLVMGANVQ VVWEKFCRYF DVEPRYLPMA EGRYVITPEQ 200
    VLDAVDEDTI GVVAILGTTY TGELEPVAEI CEALDKLAAG GGVDVPVHVD 250
    AASGGFVVPF IHPDLVWDFR LPRVVSINVS GHKYGLTYPG VGFVVWRNKE 300
    HLPEELVFRV NYLGGDMPTF TLNFSRPGNQ VVGQYYNFLR LGRAGYTQVM 350
    QCLSQTARWL GDELRDSEHF ELISDGSAIP VVAFRLKGDP GYTEFDISQA 400
    LRAHGWQVPA YTMPEGAEDV VVLRVVVREG FSADLARALK DDIITVLGQL 450
    DALKPRGQFD QLQPFAH 467
    Length:467
    Mass (Da):51,621
    Last modified:October 3, 2012 - v1
    Checksum:iCCAD54F06D09D1DD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001663 Genomic DNA. Translation: AFP38009.1.
    RefSeqiYP_006566304.1. NC_018289.1.

    Genome annotation databases

    EnsemblBacteriaiAFP38009; AFP38009; MSMEI_1536.
    KEGGimsg:MSMEI_1536.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001663 Genomic DNA. Translation: AFP38009.1 .
    RefSeqi YP_006566304.1. NC_018289.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AFP38009 ; AFP38009 ; MSMEI_1536 .
    KEGGi msg:MSMEI_1536.

    Phylogenomic databases

    KOi K01580.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    InterProi IPR010107. Glutamate_decarboxylase.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view ]
    PANTHERi PTHR11999:SF1. PTHR11999:SF1. 1 hit.
    Pfami PF00282. Pyridoxal_deC. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53383. SSF53383. 1 hit.
    TIGRFAMsi TIGR01788. Glu-decarb-GAD. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Interrupted coding sequences in Mycobacterium smegmatis: authentic mutations or sequencing errors?"
      Deshayes C., Perrodou E., Gallien S., Euphrasie D., Schaeffer C., Van-Dorsselaer A., Poch O., Lecompte O., Reyrat J.-M.
      Genome Biol. 8:R20.1-R20.9(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700084 / mc(2)155Imported.
    2. "Ortho-proteogenomics: multiple proteomes investigation through orthology and a new MS-based protocol."
      Gallien S., Perrodou E., Carapito C., Deshayes C., Reyrat J.-M., Van Dorsselaer A., Poch O., Schaeffer C., Lecompte O.
      Genome Res. 19:128-135(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

    Entry informationi

    Entry nameiI7G5Y1_MYCS2
    AccessioniPrimary (citable) accession number: I7G5Y1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 3, 2012
    Last sequence update: October 3, 2012
    Last modified: October 1, 2014
    This is version 12 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3