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I7DEM4

- I7DEM4_HUMAN

UniProt

I7DEM4 - I7DEM4_HUMAN

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Protein
Submitted name:

MHC class I antigen

Gene
HLA-C
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. peptide antigen binding Source: InterPro

GO - Biological processi

  1. antigen processing and presentation of peptide antigen via MHC class I Source: InterPro
  2. immune response Source: InterPro
  3. positive regulation of T cell mediated cytotoxicity Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
MHC class I antigenImported
Gene namesi
Name:HLA-CImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. MHC class I protein complex Source: InterPro
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiI7DEM4.

Structurei

3D structure databases

ProteinModelPortaliI7DEM4.

Family & Domainsi

Sequence similaritiesi

Belongs to the MHC class I family.UniRule annotation

Family and domain databases

Gene3Di3.30.500.10. 1 hit.
InterProiIPR011161. MHC_I-like_Ag-recog.
IPR011162. MHC_I/II-like_Ag-recog.
IPR027648. MHC_I_a.
IPR001039. MHC_I_a_a1/a2.
[Graphical view]
PfamiPF00129. MHC_I. 1 hit.
[Graphical view]
PRINTSiPR01638. MHCCLASSI.
SUPFAMiSSF54452. SSF54452. 1 hit.

Sequencei

Sequence statusi: Fragment.

I7DEM4-1 [UniParc]FASTAAdd to Basket

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SHSMRYFYTA VSRPGRGEPH FIAVGYVDDT QFVRFDSDAA SPRGEPRAPW    50
VEQEGPEYWD RETQKYKRQA QTDRVSLRNL RGYYNQSEAG SHIIQRMYGC 100
DVGPDGRLLR GYDQYAYDGK DYIALNEDLR SWTAADTAAQ ITQRKWEAAR 150
EAEQLRAYLE GLCVEWLRRY LKNGKETLQR A 181
Length:181
Mass (Da):21,116
Last modified:October 3, 2012 - v1
Checksum:i21BC930D6F82CEBD
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei181 – 1811Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
JX049547 Genomic DNA. Translation: AFO66766.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
JX049547 Genomic DNA. Translation: AFO66766.1 .

3D structure databases

ProteinModelPortali I7DEM4.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi I7DEM4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

ChiTaRSi HLA-C. human.
NextBioi 35534566.

Family and domain databases

Gene3Di 3.30.500.10. 1 hit.
InterProi IPR011161. MHC_I-like_Ag-recog.
IPR011162. MHC_I/II-like_Ag-recog.
IPR027648. MHC_I_a.
IPR001039. MHC_I_a_a1/a2.
[Graphical view ]
Pfami PF00129. MHC_I. 1 hit.
[Graphical view ]
PRINTSi PR01638. MHCCLASSI.
SUPFAMi SSF54452. SSF54452. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cereb N., Yang S.Y.
    Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiI7DEM4_HUMAN
AccessioniPrimary (citable) accession number: I7DEM4
Entry historyi
Integrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: October 16, 2013
This is version 9 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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