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I7BM23 (I7BM23_ENTFL) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 12. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein attributes

Sequence length194 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + thymidine = ADP + thymidine 5'-phosphate. HAMAP-Rule MF_00124 RuleBase RU000544 SAAS SAAS020634

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00124 SAAS SAAS020634

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00124 SAAS SAAS020634.

Sequence similarities

Belongs to the thymidine kinase family. HAMAP-Rule MF_00124

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding9 – 168ATP By similarity HAMAP-Rule MF_00124
Nucleotide binding85 – 884ATP By similarity HAMAP-Rule MF_00124

Sites

Active site861Proton acceptor By similarity HAMAP-Rule MF_00124
Metal binding1431Zinc By similarity HAMAP-Rule MF_00124
Metal binding1461Zinc By similarity HAMAP-Rule MF_00124
Metal binding1801Zinc By similarity HAMAP-Rule MF_00124
Metal binding1831Zinc By similarity HAMAP-Rule MF_00124

Sequences

Sequence LengthMass (Da)Tools
I7BM23 [UniParc].

Last modified October 3, 2012. Version 1.
Checksum: 9EC53D1FB3EA6C3C

FASTA19422,466
        10         20         30         40         50         60 
MAQLFFKYGA MNSGKTIEIL KVAHNYEEQD KPVVLMTSGL DTRDGVGKVS SRIGLRRDAI 

        70         80         90        100        110        120 
PIFEETNVFD LINDLSYKPF CVLVDECQFL NKHHVIEFAR IVDELDIPVM AFGLKNDFRN 

       130        140        150        160        170        180 
ELFEGSKYLL LYADKLEELK TICWFCHKKA TMNLHYIDGK PVYEGDQVQI GGNEAYYPVC 

       190 
RKHYFHPKTV NEEQ 

« Hide

References

[1]"Complete Genome Sequence of the Porcine Isolate Enterococcus faecalis D32."
Zischka M., Kuenne C., Blom J., Dabrowski P.W., Linke B., Hain T., Nitsche A., Goesmann A., Larsen J., Jensen L.B., Witte W., Werner G.
J. Bacteriol. 194:5490-5491(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: D32 EMBL AFO45007.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003726 Genomic DNA. Translation: AFO45007.1.
RefSeqYP_006538483.1. NC_018221.1.

3D structure databases

ProteinModelPortalI7BM23.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFO45007; AFO45007; EFD32_2124.
GeneID13346152.
KEGGefd:EFD32_2124.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00857.

Enzyme and pathway databases

BioCycEFAE1206105:GLCS-2172-MONOMER.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
HAMAPMF_00124. Thymidine_kinase.
InterProIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERPTHR11441. PTHR11441. 1 hit.
PfamPF00265. TK. 1 hit.
[Graphical view]
PIRSFPIRSF035805. TK_cell. 1 hit.
SUPFAMSSF52540. SSF52540. 1 hit.
PROSITEPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameI7BM23_ENTFL
AccessionPrimary (citable) accession number: I7BM23
Entry history
Integrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: June 11, 2014
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)