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I7AYA5

- I7AYA5_HUMAN

UniProt

I7AYA5 - I7AYA5_HUMAN

Protein
Submitted name:

MHC class I antigen

Gene

HLA-C

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein inferred from homologyi
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    • History
      Entry version 10 (01 Oct 2014)
      Sequence version 1 (03 Oct 2012)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. peptide antigen binding Source: InterPro

    GO - Biological processi

    1. antigen processing and presentation of peptide antigen via MHC class I Source: InterPro
    2. immune response Source: InterPro
    3. positive regulation of T cell mediated cytotoxicity Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    MHC class I antigenImported
    Gene namesi
    Name:HLA-CImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. MHC class I protein complex Source: InterPro

    PTM / Processingi

    Proteomic databases

    PRIDEiI7AYA5.

    Structurei

    3D structure databases

    ProteinModelPortaliI7AYA5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the MHC class I family.UniRule annotation

    Family and domain databases

    Gene3Di3.30.500.10. 1 hit.
    InterProiIPR011161. MHC_I-like_Ag-recog.
    IPR011162. MHC_I/II-like_Ag-recog.
    IPR027648. MHC_I_a.
    IPR001039. MHC_I_a_a1/a2.
    [Graphical view]
    PfamiPF00129. MHC_I. 1 hit.
    [Graphical view]
    PRINTSiPR01638. MHCCLASSI.
    SUPFAMiSSF54452. SSF54452. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    I7AYA5-1 [UniParc]FASTAAdd to Basket

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    SHSMRYFSTS VSWPGRGEPR FIAVGYVDDT QFVRFDSDAA SPRGEPREPW    50
    VEQEGPEYWD RETQKYKRQA QADRVNLRKL RGYYNQSEDG SHTLQRMFGC 100
    DLGPDGRLLR GYNQFAYDGK DYIALNEDLR SWTAADTAAQ ITQRKWEAAR 150
    EAEQRRAYLE GTCVEWLRRY LENGKETLQR A 181
    Length:181
    Mass (Da):21,219
    Last modified:October 3, 2012 - v1
    Checksum:i93D08DECD4BBDD18
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported
    Non-terminal residuei181 – 1811Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    JQ997146 Genomic DNA. Translation: AFN88168.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    JQ997146 Genomic DNA. Translation: AFN88168.1 .

    3D structure databases

    ProteinModelPortali I7AYA5.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi I7AYA5.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Miscellaneous databases

    ChiTaRSi HLA-C. human.
    NextBioi 35534513.

    Family and domain databases

    Gene3Di 3.30.500.10. 1 hit.
    InterProi IPR011161. MHC_I-like_Ag-recog.
    IPR011162. MHC_I/II-like_Ag-recog.
    IPR027648. MHC_I_a.
    IPR001039. MHC_I_a_a1/a2.
    [Graphical view ]
    Pfami PF00129. MHC_I. 1 hit.
    [Graphical view ]
    PRINTSi PR01638. MHCCLASSI.
    SUPFAMi SSF54452. SSF54452. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cereb N., Yang S.Y.
      Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiI7AYA5_HUMAN
    AccessioniPrimary (citable) accession number: I7AYA5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 3, 2012
    Last sequence update: October 3, 2012
    Last modified: October 1, 2014
    This is version 10 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.