I6YG46 (I6YG46_MYCTU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Glutamate decarboxylase EMBL AFN51450.1

Gene names

ORF Names:

RVBD_3432c EMBL AFN51450.1

Organism

Mycobacterium tuberculosis H37Rv EMBL AFN51450.1

Taxonomic identifier

83332 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex › Mycobacterium tuberculosis

Protein attributes

Sequence length	460 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000382
Sequence similarities	Belongs to the group II decarboxylase family. RuleBase RU000382

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU000382
Molecular function	Lyase RuleBase RU000382
Gene Ontology (GO)
Biological_process	glutamate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	glutamate decarboxylase activity Inferred from electronic annotation. Source: InterPro pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	I6YG46 [UniParc]. Last modified October 3, 2012. Version 1. Checksum: B5DA3156D4C7CB4F	FASTA	460	50,780
	10 20 30 40 50 60 MSRSHPSVPA HSIAPAYTGR MFTAPVPALR MPDESMDPEA AYRFIHDELM LDGSSRLNLA 70 80 90 100 110 120 TFVTTWMDPE AEKLMAETFD KNMIDKDEYP ATAAIEARCV SMVADLFHAE GLRDHDPTSA 130 140 150 160 170 180 TGVSTIGSSE AVMLGGLALK WRWRQRVGSW KGRMPNLVMG SNVQVVWEKF CRYFDVEPRY 190 200 210 220 230 240 LPMERGRYVI TPEQVLAAVD ENTIGVVAIL GTTYTGELEP IAEICAALDK LAAGGGVDVP 250 260 270 280 290 300 VHVDAASGGF VVPFLHPDLV WDFRLPRVVS INVSGHKYGL TYPGVGFVVW RGPEHLPEDL 310 320 330 340 350 360 VFRVNYLGGD MPTFTLNFSR PGNQVVGQYY NFLRLGRDGY TKVMQALSHT ARWLGDQLRE 370 380 390 400 410 420 VDHCEVISDG SAIPVVSFRL AGDRGYTEFD VSHELRTFGW QVPAYTMPDN ATDVAVLRIV 430 440 450 460 VREGLSADLA RALHDDAVTA LAALDKVKPG GHFDAQHFAH

References

[1]

"The Genome Sequence of Mycobacterium tuberculosis H37Rv." The Broad Institute Genome Sequencing Platform, The Broad Institute Genome Sequencing Center for Infectious Disease Galagan J., Walker B., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A. , Larimer J., McCowan C., Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B. Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: H37Rv EMBL AFN51450.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP003248 Genomic DNA. Translation: AFN51450.1.
RefSeq	NP_217949.1. NC_000962.3. YP_006516921.1. NC_018143.1.
3D structure databases
ProteinModelPortal	I6YG46.
SMR	I6YG46. Positions 12-447.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AFN51450; AFN51450; RVBD_3432c.
GeneID	13317039. 887580.
KEGG	mtu:Rv3432c.
Phylogenomic databases
KO	K01580.
OMA	PMDKEHM.
Family and domain databases
Gene3D	3.40.640.10. 1 hit.
InterPro	IPR010107. Glutamate_decarboxylase. IPR002129. PyrdxlP-dep_de-COase. IPR015424. PyrdxlP-dep_Trfase. IPR015421. PyrdxlP-dep_Trfase_major_sub1. [Graphical view]
PANTHER	PTHR11999:SF1. PTHR11999:SF1. 1 hit.
Pfam	PF00282. Pyridoxal_deC. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

I6YG46_MYCTU

Accession

Primary (citable) accession number: I6YG46

Entry history

Integrated into UniProtKB/TrEMBL:	October 3, 2012
Last sequence update:	October 3, 2012
Last modified:	May 29, 2013
This is version 9 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)