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Protein
Submitted name:

EchA16 protein

Gene

echA16

Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

LyaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
EchA16 proteinImported
Submitted name:
Enoyl-CoA hydrataseImported (EC:4.2.1.17Imported)
Gene namesi
Name:echA16Imported
Ordered Locus Names:Rv2831Imported
ORF Names:LH57_15455Imported
OrganismiMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)Imported
Taxonomic identifieri83332 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
ProteomesiUP000001584 Componenti: Chromosome UP000031768 Componenti: Chromosome

Organism-specific databases

TubercuListiRv2831.

Interactioni

Protein-protein interaction databases

STRINGi83332.Rv2831.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4JJTX-ray2.50A/B/C1-249[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

KOiK01692.
OMAiACERDPA.

Family and domain databases

Gene3Di3.90.226.10. 1 hit.
InterProiIPR029045. ClpP/crotonase-like_dom.
IPR001753. Crotonase_core_superfam.
[Graphical view]
PfamiPF00378. ECH. 1 hit.
[Graphical view]
SUPFAMiSSF52096. SSF52096. 1 hit.

Sequencei

Sequence statusi: Complete.

I6YEH6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDDILLIDT DERVRTLTLN RPQSRNALSA ALRDRFFAAL ADAEADDDID
60 70 80 90 100
VVILTGADPV FCAGLDLKEL AGQTALPDIS PRWPAMTKPV IGAINGAAVT
110 120 130 140 150
GGLELALYCD ILIASEHARF ADTHARVGLL PTWGLSVRLP QKVGIGLARR
160 170 180 190 200
MSLTGDYLSA TDALRAGLVT EVVAHDQLLP TARRVAASIV GNNQNAVRAL
210 220 230 240
LASYHRIDES QTAAGLWLEA CAAKQFRTSG DTIAANREAV LQRGRAQVR
Length:249
Mass (Da):26,630
Last modified:October 3, 2012 - v1
Checksum:i1605D9AFFE1C67F9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009480 Genomic DNA. Translation: AIR15605.1.
AL123456 Genomic DNA. Translation: CCP45632.1.
RefSeqiNP_217347.1. NC_000962.3.
WP_003414497.1. NZ_KK339370.1.
YP_006516281.1. NC_018143.2.

Genome annotation databases

EnsemblBacteriaiAFN50810; AFN50810; RVBD_2831.
CCP45632; CCP45632; Rv2831.
KBJ30217; KBJ30217; P425_02948.
GeneIDi888519.
KEGGimtu:Rv2831.
mtv:RVBD_2831.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009480 Genomic DNA. Translation: AIR15605.1.
AL123456 Genomic DNA. Translation: CCP45632.1.
RefSeqiNP_217347.1. NC_000962.3.
WP_003414497.1. NZ_KK339370.1.
YP_006516281.1. NC_018143.2.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4JJTX-ray2.50A/B/C1-249[»]
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi83332.Rv2831.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFN50810; AFN50810; RVBD_2831.
CCP45632; CCP45632; Rv2831.
KBJ30217; KBJ30217; P425_02948.
GeneIDi888519.
KEGGimtu:Rv2831.
mtv:RVBD_2831.

Organism-specific databases

TubercuListiRv2831.

Phylogenomic databases

KOiK01692.
OMAiACERDPA.

Family and domain databases

Gene3Di3.90.226.10. 1 hit.
InterProiIPR029045. ClpP/crotonase-like_dom.
IPR001753. Crotonase_core_superfam.
[Graphical view]
PfamiPF00378. ECH. 1 hit.
[Graphical view]
SUPFAMiSSF52096. SSF52096. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25618 / H37RvImported and H37RvImported.
  2. "Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv."
    Camus J.C., Pryor M.J., Medigue C., Cole S.T.
    Microbiology 148:2967-2973(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: H37RvImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: H37RvImported.
  4. Lew J.M.
    Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: H37RvImported.
  5. "The crystal structure of enoyl-CoA hydratase from Mycobacterium tuberculosis H37Rv."
    Tan K., Holowicki J., Endres M., Kim C.-Y., Kim H., Hung L.-W., Terwilliger T.C., Joachimiak A.
    Submitted (MAR-2013) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (2.50 ANGSTROMS).
  6. "Phylogenetic analysis of Mycobacterial species using whole genome sequences."
    Hazbon M.H., Riojas M.A., Damon A.M., Alalade R.O., Cantwell B.J., Monaco A., King S., Sohrabi A.
    Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 27294 / TMC 102 / H37RvImported and H37RvImported.

Entry informationi

Entry nameiI6YEH6_MYCTU
AccessioniPrimary (citable) accession number: I6YEH6
Entry historyi
Integrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: June 24, 2015
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.