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I6Y3R9

- I6Y3R9_MYCTU

UniProt

I6Y3R9 - I6Y3R9_MYCTU

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Protein
Superoxide dismutase [Cu-Zn]
Gene
P425_00445, RVBD_0432
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems By similarity.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

Cofactori

Binds 1 copper ion per subunit By similarity.UniRule annotation
Binds 1 zinc ion per subunit By similarity.UniRule annotation

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. superoxide dismutase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Ligandi

CopperUniRule annotation, Metal-bindingUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutase [Cu-Zn]UniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesi
ORF Names:P425_00445Imported, RVBD_0432Imported
OrganismiMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)Imported
Taxonomic identifieri83332 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
ProteomesiUP000003123: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the Cu-Zn superoxide dismutase family.UniRule annotation

Phylogenomic databases

KOiK04565.
OMAiYNQTNGT.
PhylomeDBiI6Y3R9.

Family and domain databases

Gene3Di2.60.40.200. 1 hit.
InterProiIPR018152. SOD_Cu/Zn_BS.
IPR001424. SOD_Cu_Zn_dom.
[Graphical view]
PfamiPF00080. Sod_Cu. 1 hit.
[Graphical view]
SUPFAMiSSF49329. SSF49329. 1 hit.
PROSITEiPS00332. SOD_CU_ZN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

I6Y3R9-1 [UniParc]FASTAAdd to Basket

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MPKPADHRNH AAVSTSVLSA LFLGAGAALL SACSSPQHAS TVPGTTPSIW    50
TGSPAPSGLS GHDEESPGAQ SLTSTLTAPD GTKVATAKFE FANGYATVTI 100
ATTGVGKLTP GFHGLHIHQV GKCEPNSVAP TGGAPGNFLS AGGHYHVPGH 150
TGTPASGDLA SLQVRGDGSA MLVTTTDAFT MDDLLSGAKT AIIIHAGADN 200
FANIPPERYV QVNGTPGPDE TTLTTGDAGK RVACGVIGSG 240
Length:240
Mass (Da):23,844
Last modified:October 3, 2012 - v1
Checksum:iAFC08C0B302B84FC
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003248 Genomic DNA. Translation: AFN48287.1.
JLDD01000005 Genomic DNA. Translation: KBJ40208.1.
RefSeqiNP_214946.1. NC_000962.3.
YP_006513758.1. NC_018143.2.

Genome annotation databases

EnsemblBacteriaiAFN48287; AFN48287; RVBD_0432.
GeneIDi13318299.
886358.
KEGGimtu:Rv0432.
mtv:RVBD_0432.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003248 Genomic DNA. Translation: AFN48287.1 .
JLDD01000005 Genomic DNA. Translation: KBJ40208.1 .
RefSeqi NP_214946.1. NC_000962.3.
YP_006513758.1. NC_018143.2.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFN48287 ; AFN48287 ; RVBD_0432 .
GeneIDi 13318299.
886358.
KEGGi mtu:Rv0432.
mtv:RVBD_0432.

Phylogenomic databases

KOi K04565.
OMAi YNQTNGT.
PhylomeDBi I6Y3R9.

Family and domain databases

Gene3Di 2.60.40.200. 1 hit.
InterProi IPR018152. SOD_Cu/Zn_BS.
IPR001424. SOD_Cu_Zn_dom.
[Graphical view ]
Pfami PF00080. Sod_Cu. 1 hit.
[Graphical view ]
SUPFAMi SSF49329. SSF49329. 1 hit.
PROSITEi PS00332. SOD_CU_ZN_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: H37RvImported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25618 / H37Rv.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: H37RvImported.

Entry informationi

Entry nameiI6Y3R9_MYCTU
AccessioniPrimary (citable) accession number: I6Y3R9
Entry historyi
Integrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: September 3, 2014
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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