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I6Y3R9

- I6Y3R9_MYCTU

UniProt

I6Y3R9 - I6Y3R9_MYCTU

Protein

Superoxide dismutase [Cu-Zn]

Gene

P425_00445

Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 20 (01 Oct 2014)
      Sequence version 1 (03 Oct 2012)
      Previous versions | rss
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    Functioni

    Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

    Catalytic activityi

    2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

    Cofactori

    Binds 1 copper ion per subunit.UniRule annotation
    Binds 1 zinc ion per subunit.UniRule annotation

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. superoxide dismutase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    OxidoreductaseUniRule annotation

    Keywords - Ligandi

    CopperUniRule annotation, Metal-bindingUniRule annotation, ZincUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Superoxide dismutase [Cu-Zn]UniRule annotation (EC:1.15.1.1UniRule annotation)
    Gene namesi
    ORF Names:P425_00445Imported, RVBD_0432Imported
    OrganismiMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)Imported
    Taxonomic identifieri83332 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
    ProteomesiUP000003123: Chromosome

    Structurei

    3D structure databases

    SMRiI6Y3R9. Positions 70-240.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the Cu-Zn superoxide dismutase family.UniRule annotation

    Phylogenomic databases

    KOiK04565.
    OMAiYNQTNGT.
    PhylomeDBiI6Y3R9.

    Family and domain databases

    Gene3Di2.60.40.200. 1 hit.
    InterProiIPR018152. SOD_Cu/Zn_BS.
    IPR001424. SOD_Cu_Zn_dom.
    [Graphical view]
    PfamiPF00080. Sod_Cu. 1 hit.
    [Graphical view]
    SUPFAMiSSF49329. SSF49329. 1 hit.
    PROSITEiPS00332. SOD_CU_ZN_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    I6Y3R9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPKPADHRNH AAVSTSVLSA LFLGAGAALL SACSSPQHAS TVPGTTPSIW    50
    TGSPAPSGLS GHDEESPGAQ SLTSTLTAPD GTKVATAKFE FANGYATVTI 100
    ATTGVGKLTP GFHGLHIHQV GKCEPNSVAP TGGAPGNFLS AGGHYHVPGH 150
    TGTPASGDLA SLQVRGDGSA MLVTTTDAFT MDDLLSGAKT AIIIHAGADN 200
    FANIPPERYV QVNGTPGPDE TTLTTGDAGK RVACGVIGSG 240
    Length:240
    Mass (Da):23,844
    Last modified:October 3, 2012 - v1
    Checksum:iAFC08C0B302B84FC
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003248 Genomic DNA. Translation: AFN48287.1.
    JLDD01000005 Genomic DNA. Translation: KBJ40208.1.
    RefSeqiNP_214946.1. NC_000962.3.
    YP_006513758.1. NC_018143.2.

    Genome annotation databases

    EnsemblBacteriaiAFN48287; AFN48287; RVBD_0432.
    GeneIDi13318299.
    886358.
    KEGGimtu:Rv0432.
    mtv:RVBD_0432.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003248 Genomic DNA. Translation: AFN48287.1 .
    JLDD01000005 Genomic DNA. Translation: KBJ40208.1 .
    RefSeqi NP_214946.1. NC_000962.3.
    YP_006513758.1. NC_018143.2.

    3D structure databases

    SMRi I6Y3R9. Positions 70-240.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AFN48287 ; AFN48287 ; RVBD_0432 .
    GeneIDi 13318299.
    886358.
    KEGGi mtu:Rv0432.
    mtv:RVBD_0432.

    Phylogenomic databases

    KOi K04565.
    OMAi YNQTNGT.
    PhylomeDBi I6Y3R9.

    Family and domain databases

    Gene3Di 2.60.40.200. 1 hit.
    InterProi IPR018152. SOD_Cu/Zn_BS.
    IPR001424. SOD_Cu_Zn_dom.
    [Graphical view ]
    Pfami PF00080. Sod_Cu. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49329. SSF49329. 1 hit.
    PROSITEi PS00332. SOD_CU_ZN_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: H37RvImported.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 25618 / H37RvImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: H37RvImported.

    Entry informationi

    Entry nameiI6Y3R9_MYCTU
    AccessioniPrimary (citable) accession number: I6Y3R9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 3, 2012
    Last sequence update: October 3, 2012
    Last modified: October 1, 2014
    This is version 20 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3