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Protein
Submitted name:

Polyketide synthase

Gene

LH57_16005

Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Polyketide synthaseImported
Gene namesi
ORF Names:LH57_16005Imported
OrganismiMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)Imported
Taxonomic identifieri83332 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000031768 Componenti: Chromosome

PTM / Processingi

Proteomic databases

PaxDbiI6Y228.
PRIDEiI6Y228.

Structurei

3D structure databases

ProteinModelPortaliI6Y228.
SMRiI6Y228.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini935 – 1001CarrierInterPro annotationAdd BLAST67

Phylogenomic databases

eggNOGiENOG4107EEY. Bacteria.
COG3321. LUCA.
KOiK12444.
OMAiWSQRCAG.
PhylomeDBiI6Y228.

Family and domain databases

Gene3Di1.10.1200.10. 1 hit.
3.30.70.250. 1 hit.
3.40.47.10. 2 hits.
InterProiView protein in InterPro
IPR036736. ACP-like_sf.
IPR014043. Acyl_transferase.
IPR016035. Acyl_Trfase/lysoPLipase.
IPR001242. Condensatn.
IPR032821. KAsynt_C_assoc.
IPR018201. Ketoacyl_synth_AS.
IPR014031. Ketoacyl_synth_C.
IPR014030. Ketoacyl_synth_N.
IPR016036. Malonyl_transacylase_ACP-bd.
IPR020801. PKS_acyl_transferase.
IPR020841. PKS_Beta-ketoAc_synthase_dom.
IPR020806. PKS_PP-bd.
IPR009081. PP-bd_ACP.
IPR016039. Thiolase-like.
PfamiView protein in Pfam
PF00698. Acyl_transf_1. 1 hit.
PF00668. Condensation. 1 hit.
PF16197. KAsynt_C_assoc. 1 hit.
PF00109. ketoacyl-synt. 1 hit.
PF02801. Ketoacyl-synt_C. 1 hit.
PF00550. PP-binding. 1 hit.
SMARTiView protein in SMART
SM00827. PKS_AT. 1 hit.
SM00825. PKS_KS. 1 hit.
SM00823. PKS_PP. 1 hit.
SUPFAMiSSF47336. SSF47336. 1 hit.
SSF52151. SSF52151. 2 hits.
SSF53901. SSF53901. 3 hits.
SSF55048. SSF55048. 1 hit.
PROSITEiView protein in PROSITE
PS50075. ACP_DOMAIN. 1 hit.
PS00606. B_KETOACYL_SYNTHASE. 1 hit.

Sequencei

Sequence statusi: Complete.

I6Y228-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSIPENAIAV VGMAGRFPGA KDVSAFWSNL RRGKESIVTL SEQELRDAGV
60 70 80 90 100
SDKTLADPAY VRRAPLLDGI DEFDAGFFGF PPLAAQVLDP QHRLFLQCAW
110 120 130 140 150
HALEDAGADP ARFDGSIGVY GTSSPSGYLL HNLLSHRDPN AVLAEGLNFD
160 170 180 190 200
QFSLFLQNDK DFLATRISHA FNLRGPSIAV QTACSSSLVA VHLACLSLLS
210 220 230 240 250
GECDMALAGG SSLCIPHRVG YFTSPGSMVS AVGHCRPFDV RADGTVFGSG
260 270 280 290 300
VGLVVLKPLA AAIDAGDRIH AVIRGSAINN DGSAKMGYAA PNPAAQADVI
310 320 330 340 350
AEAHAVSGID SSTVSYVECH GTGTPLGDPI EIQGLRAAFE VSQTSRSAPC
360 370 380 390 400
VLGSVKSNIG HLEVAAGIAG LIKTILCLKN KALPATLHYT SPNPELRLDQ
410 420 430 440 450
SPFVVQSKYG PWECDGVRRA GVSSFGVGGT NAHVVLEEAP AEASEVSAHA
460 470 480 490 500
EPAGPQVILL SAQTAAALGE SRTALAAALE TQDGPRLSDV AYTLARRRKH
510 520 530 540 550
NVTMAAVVHD REHAATVLRA AEHDNVFVGE AAHDGEHGDR ADAAPTSDRV
560 570 580 590 600
VFLFPGQGAQ HVGMAKGLYD TEPVFAQHFD TCAAGFRDET GIDLHAEVFD
610 620 630 640 650
GTATDLERID RSQPALFTVE YALAKLVDTF GVRAGAYIGY STGEYIAATL
660 670 680 690 700
AGVFDLQTAI KTVSLRARLM HESPPGAMVA VALGPDDVTQ YLPPEVELSA
710 720 730 740 750
VNDPGNCVVA GPKDQIRALR QRLTEAGIPV RRVRATHAFH TSAMDPMLGQ
760 770 780 790 800
FQEFLSRQQL RPPRTPLLSN LTGSWMSDQQ VVDPASWTRQ ISSPIRFADE
810 820 830 840 850
LDVVLAAPSR ILVEVGPGGS LTGSAMRHPK WSTTHRTVRL MRHPLQDVDD
860 870 880 890 900
RDTFLRALGE LWSAGVEVDW TPRRPAVPHL VSLPGYPFAR QRHWVEPNHT
910 920 930 940 950
VWAQAPGANN GSPAGTADGS TAATVDAARN GESQTEVTLQ RIWSQCLGVS
960 970 980 990 1000
SVDRNANFFD LGGDSLMAIS IAMAAANEGL TITPQDLYEY PTLASLTAAV
1010 1020 1030 1040 1050
DASFASSGLA KPPEAQANPA VPPNVTYFLD RGLRDTGRCR VPLILRLDPK
1060 1070 1080 1090 1100
IGLPDIRAVL TAVVNHHDAL RLHLVGNDGI WEQHIAAPAE FTGLSNRSVP
1110 1120 1130 1140 1150
NGVAAGSPEE RAAVLGILAE LLEDQTDPNA PLAAVHIAAA HGGPHYLCLA
1160 1170 1180 1190 1200
IHAMVTDDSS RQILATDIVT AFGQRLAGEE ITLEPVSTGW REWSLRCAAL
1210 1220 1230 1240 1250
ATHPAALDTR SYWIENSTKA TLWLADALPN AHTAHPPRAD ELTKLSSTLS
1260 1270 1280 1290 1300
VEQTSELDDG RRRFRRSIQT ILLAALGRTI AQTVGEGVVA VELEGEGRSV
1310 1320 1330 1340 1350
LRPDVDLRRT VGWFTTYYPV PLACATGLGA LAQLDAVHNT LKSVPHYGIG
1360 1370 1380 1390 1400
YGLLRYVYAP TGRVLGAQRT PDIHFRYAGV IPELPSGDAP VQFDSDMTLP
1410 1420 1430 1440 1450
VREPIPGMGH AIELRVYRFG GSLHLDWWYD TRRIPAATAE ALERTFPLAL
1460 1470 1480
SALIQEAIAA EHTEHDDSEI VGEPEAGALV DLSSMDAG
Length:1,488
Mass (Da):158,745
Last modified:October 3, 2012 - v1
Checksum:iC6418D88A27BB701
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009480 Genomic DNA. Translation: AIR15710.1.
RefSeqiNP_217451.1. NC_000962.3.
WP_003900602.1. NZ_KK339370.1.

Genome annotation databases

EnsemblBacteriaiAIR15710; AIR15710; LH57_16005.
GeneIDi888210.
KEGGimtu:Rv2935.
mtv:RVBD_2935.
PATRICifig|83332.111.peg.3265.

Similar proteinsi

Entry informationi

Entry nameiI6Y228_MYCTU
AccessioniPrimary (citable) accession number: I6Y228
Entry historyiIntegrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: October 25, 2017
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Keywords - Technical termi

Complete proteomeImported