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I6XWL7

- I6XWL7_MYCTU

UniProt

I6XWL7 - I6XWL7_MYCTU

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Protein
Submitted name:

ATP dependent DNA ligase LigD

Gene

RVBD_0938

Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. DNA ligase (ATP) activity Source: InterPro
  3. DNA primase activity Source: InterPro

GO - Biological processi

  1. DNA recombination Source: InterPro
  2. DNA repair Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LigaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
ATP dependent DNA ligase LigDImported
Submitted name:
ATP-dependent DNA ligaseImported (EC:6.5.1.1Imported)
Gene namesi
Ordered Locus Names:RVBD_0938Imported
ORF Names:LH57_05110Imported, P425_00979Imported
OrganismiMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)Imported
Taxonomic identifieri83332 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
ProteomesiUP000003123: Chromosome

Family & Domainsi

Phylogenomic databases

KOiK01971.
OMAiSKGIHLY.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
InterProiIPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR014146. DNA_pol_LigD_ligase_dom.
IPR002755. DNA_primase_S.
IPR014144. LigD_PE_domain.
IPR014145. LigD_pol.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF01896. DNA_primase_S. 1 hit.
PF13298. LigD_N. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR02777. LigD_PE_dom. 1 hit.
TIGR02778. ligD_pol. 1 hit.
TIGR02779. NHEJ_ligase_lig. 1 hit.
PROSITEiPS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

I6XWL7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGSASEQRVT LTNADKVLYP ATGTTKSDIF DYYAGVAEVM LGHIAGRPAT
60 70 80 90 100
RKRWPNGVDQ PAFFEKQLAL SAPPWLSRAT VAHRSGTTTY PIIDSATGLA
110 120 130 140 150
WIAQQAALEV HVPQWRFVAE PGSGELNPGP ATRLVFDLDP GEGVMMAQLA
160 170 180 190 200
EVARAVRDLL ADIGLVTFPV TSGSKGLHLY TPLDEPVSSR GATVLAKRVA
210 220 230 240 250
QRLEQAMPAL VTSTMTKSLR AGKVFVDWSQ NSGSKTTIAP YSLRGRTHPT
260 270 280 290 300
VAAPRTWAEL DDPALRQLSY DEVLTRIARD GDLLERLDAD APVADRLTRY
310 320 330 340 350
RRMRDASKTP EPIPTAKPVT GDGNTFVIQE HHARRPHYDF RLECDGVLVS
360 370 380 390 400
WAVPKNLPDN TSVNHLAIHT EDHPLEYATF EGAIPSGEYG AGKVIIWDSG
410 420 430 440 450
TYDTEKFHDD PHTGEVIVNL HGGRISGRYA LIRTNGDRWL AHRLKNQKDQ
460 470 480 490 500
KVFEFDNLAP MLATHGTVAG LKASQWAFEG KWDGYRLLVE ADHGAVRLRS
510 520 530 540 550
RSGRDVTAEY PQLRALAEDL ADHHVVLDGE AVVLDSSGVP SFSQMQNRGR
560 570 580 590 600
DTRVEFWAFD LLYLDGRALL GTRYQDRRKL LETLANATSL TVPELLPGDG
610 620 630 640 650
AQAFACSRKH GWEGVIAKRR DSRYQPGRRC ASWVKDKHWN TQEVVIGGWR
660 670 680 690 700
AGEGGRSSGV GSLLMGIPGP GGLQFAGRVG TGLSERELAN LKEMLAPLHT
710 720 730 740 750
DESPFDVPLP ARDAKGITYV KPALVAEVRY SEWTPEGRLR QSSWRGLRPD

KKPSEVVRE
Length:759
Mass (Da):83,572
Last modified:October 3, 2012 - v1
Checksum:i81BD49222EE09E36
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003248 Genomic DNA. Translation: AFN48823.1.
CP009480 Genomic DNA. Translation: AIR13672.1.
JLDD01000009 Genomic DNA. Translation: KBJ38700.1.
RefSeqiNP_215453.1. NC_000962.3.
YP_006514294.1. NC_018143.2.

Genome annotation databases

EnsemblBacteriaiAFN48823; AFN48823; RVBD_0938.
GeneIDi13318846.
885561.
KEGGimtu:Rv0938.
mtv:RVBD_0938.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003248 Genomic DNA. Translation: AFN48823.1 .
CP009480 Genomic DNA. Translation: AIR13672.1 .
JLDD01000009 Genomic DNA. Translation: KBJ38700.1 .
RefSeqi NP_215453.1. NC_000962.3.
YP_006514294.1. NC_018143.2.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFN48823 ; AFN48823 ; RVBD_0938 .
GeneIDi 13318846.
885561.
KEGGi mtu:Rv0938.
mtv:RVBD_0938.

Phylogenomic databases

KOi K01971.
OMAi SKGIHLY.

Family and domain databases

Gene3Di 2.40.50.140. 1 hit.
InterProi IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR014146. DNA_pol_LigD_ligase_dom.
IPR002755. DNA_primase_S.
IPR014144. LigD_PE_domain.
IPR014145. LigD_pol.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
Pfami PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF01896. DNA_primase_S. 1 hit.
PF13298. LigD_N. 1 hit.
[Graphical view ]
SUPFAMi SSF50249. SSF50249. 1 hit.
TIGRFAMsi TIGR02777. LigD_PE_dom. 1 hit.
TIGR02778. ligD_pol. 1 hit.
TIGR02779. NHEJ_ligase_lig. 1 hit.
PROSITEi PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25618 / H37RvImported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: H37RvImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: H37RvImported.
  4. "Phylogenetic analysis of Mycobacterial species using whole genome sequences."
    Hazbon M.H., Riojas M.A., Damon A.M., Alalade R.O., Cantwell B.J., Monaco A., King S., Sohrabi A.
    Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: H37RvImported.

Entry informationi

Entry nameiI6XWL7_MYCTU
AccessioniPrimary (citable) accession number: I6XWL7
Entry historyi
Integrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: November 26, 2014
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3