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I6W118

- I6W118_KLEOX

UniProt

I6W118 - I6W118_KLEOX

Protein

Xylose isomerase

Gene

xylA

Organism
Klebsiella oxytoca E718
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 17 (01 Oct 2014)
      Sequence version 1 (03 Oct 2012)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

    Cofactori

    Binds 2 magnesium ions per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei101 – 1011UniRule annotation
    Active sitei104 – 1041UniRule annotation
    Metal bindingi232 – 2321Magnesium 1UniRule annotation
    Metal bindingi268 – 2681Magnesium 1UniRule annotation
    Metal bindingi268 – 2681Magnesium 2UniRule annotation
    Metal bindingi271 – 2711Magnesium 2UniRule annotation
    Metal bindingi296 – 2961Magnesium 1UniRule annotation
    Metal bindingi307 – 3071Magnesium 2UniRule annotation
    Metal bindingi309 – 3091Magnesium 2UniRule annotation
    Metal bindingi339 – 3391Magnesium 1UniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. xylose isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-xylose metabolic process Source: UniProtKB-HAMAP
    2. pentose-phosphate shunt Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Biological processi

    Carbohydrate metabolism, Pentose shuntUniRule annotationSAAS annotation, Xylose metabolismUniRule annotationSAAS annotation

    Keywords - Ligandi

    MagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciKOXY1191061:GLEY-5595-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
    Gene namesi
    Name:xylAUniRule annotation
    ORF Names:A225_5595Imported
    OrganismiKlebsiella oxytoca E718Imported
    Taxonomic identifieri1191061 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
    ProteomesiUP000003127: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotationSAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotationSAAS annotation

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotationSAAS annotation

    Structurei

    3D structure databases

    ProteinModelPortaliI6W118.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the xylose isomerase family.UniRule annotation

    Phylogenomic databases

    KOiK01805.

    Family and domain databases

    Gene3Di3.20.20.150. 1 hit.
    HAMAPiMF_00455. Xylose_isom_A.
    InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
    IPR013452. Xylose_isom_bac.
    IPR001998. Xylose_isomerase.
    [Graphical view]
    PfamiPF01261. AP_endonuc_2. 1 hit.
    [Graphical view]
    PRINTSiPR00688. XYLOSISMRASE.
    SUPFAMiSSF51658. SSF51658. 1 hit.
    TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
    PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    I6W118-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQTYFDQLDR VRYEGPKSAN PLAFRHYNPD ELVLGKRMEE HLRFAACYWH    50
    TFCWNGADMF GVGSFNRPWQ QPGEALEMAK RKADVAFEFF QKLNVPYYCF 100
    HDVDVSPEGA SLKEYANNFA QMVDVLAEKQ QQSGVKLLWG TANCFTNPRY 150
    GAGAATNPDP EVFSWAATQV VTAMDATHKL GGENYVLWGG REGYETLLNT 200
    DLRQEREQIG RFMQLVVEHK HKIGFQGTLL IEPKPQEPTK HQYDYDASTV 250
    YGFLKQFGLE KEIKLNIEAN HATLAGHTFH HEIATAIALG LFGSVDANRG 300
    DPQLGWDTDQ FPNSVEENAL VMYEILKAGG FTTGGLNFDA KVRRQSTDKY 350
    DLFYGHIGAM DTMALALKVA ARMIEDGELD KRVARRYAGW NGELGQQILK 400
    GQMNLADIAQ YATQHNLAPE HQSGHQELLE NVVNRYLFDR 440
    Length:440
    Mass (Da):49,837
    Last modified:October 3, 2012 - v1
    Checksum:i7E3EB4FEF8D938AD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003683 Genomic DNA. Translation: AFN34687.1.
    RefSeqiWP_014227204.1. NC_018106.1.
    YP_006501256.1. NC_018106.1.

    Genome annotation databases

    EnsemblBacteriaiAFN34687; AFN34687; A225_5595.
    GeneIDi13310100.
    KEGGikoe:A225_5595.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003683 Genomic DNA. Translation: AFN34687.1 .
    RefSeqi WP_014227204.1. NC_018106.1.
    YP_006501256.1. NC_018106.1.

    3D structure databases

    ProteinModelPortali I6W118.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AFN34687 ; AFN34687 ; A225_5595 .
    GeneIDi 13310100.
    KEGGi koe:A225_5595.

    Phylogenomic databases

    KOi K01805.

    Enzyme and pathway databases

    BioCyci KOXY1191061:GLEY-5595-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.150. 1 hit.
    HAMAPi MF_00455. Xylose_isom_A.
    InterProi IPR013022. Xyl_isomerase-like_TIM-brl.
    IPR013452. Xylose_isom_bac.
    IPR001998. Xylose_isomerase.
    [Graphical view ]
    Pfami PF01261. AP_endonuc_2. 1 hit.
    [Graphical view ]
    PRINTSi PR00688. XYLOSISMRASE.
    SUPFAMi SSF51658. SSF51658. 1 hit.
    TIGRFAMsi TIGR02630. xylose_isom_A. 1 hit.
    PROSITEi PS51415. XYLOSE_ISOMERASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete Genome Sequence of Klebsiella oxytoca E718, a New Delhi Metallo-beta-Lactamase-1-Producing Nosocomial Strain."
      Liao T.L., Lin A.C., Chen E., Huang T.W., Liu Y.M., Chang Y.H., Lai J.F., Lauderdale T.L., Wang J.T., Chang S.C., Tsai S.F., Chen Y.T.
      J. Bacteriol. 194:5454-5454(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: E718Imported.

    Entry informationi

    Entry nameiI6W118_KLEOX
    AccessioniPrimary (citable) accession number: I6W118
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 3, 2012
    Last sequence update: October 3, 2012
    Last modified: October 1, 2014
    This is version 17 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3