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I6W118

- I6W118_KLEOX

UniProt

I6W118 - I6W118_KLEOX

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Protein

Xylose isomerase

Gene
xylA, A225_5595
Organism
Klebsiella oxytoca E718
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotations

Cofactori

Binds 2 magnesium ions per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei101 – 1011 By similarityUniRule annotation
Active sitei104 – 1041 By similarityUniRule annotation
Metal bindingi232 – 2321Magnesium 1 By similarityUniRule annotation
Metal bindingi268 – 2681Magnesium 1 By similarityUniRule annotation
Metal bindingi268 – 2681Magnesium 2 By similarityUniRule annotation
Metal bindingi271 – 2711Magnesium 2 By similarityUniRule annotation
Metal bindingi296 – 2961Magnesium 1 By similarityUniRule annotation
Metal bindingi307 – 3071Magnesium 2 By similarityUniRule annotation
Metal bindingi309 – 3091Magnesium 2 By similarityUniRule annotation
Metal bindingi339 – 3391Magnesium 1 By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. xylose isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-xylose metabolic process Source: UniProtKB-HAMAP
  2. pentose-phosphate shunt Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Biological processi

Carbohydrate metabolism, Pentose shuntUniRule annotationSAAS annotations, Xylose metabolismUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotations, Metal-bindingUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciKOXY1191061:GLEY-5595-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotation
ORF Names:A225_5595Imported
OrganismiKlebsiella oxytoca E718Imported
Taxonomic identifieri1191061 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
ProteomesiUP000003127: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotationSAAS annotations

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotations

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotationSAAS annotations

Structurei

3D structure databases

ProteinModelPortaliI6W118.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK01805.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

I6W118-1 [UniParc]FASTAAdd to Basket

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MQTYFDQLDR VRYEGPKSAN PLAFRHYNPD ELVLGKRMEE HLRFAACYWH    50
TFCWNGADMF GVGSFNRPWQ QPGEALEMAK RKADVAFEFF QKLNVPYYCF 100
HDVDVSPEGA SLKEYANNFA QMVDVLAEKQ QQSGVKLLWG TANCFTNPRY 150
GAGAATNPDP EVFSWAATQV VTAMDATHKL GGENYVLWGG REGYETLLNT 200
DLRQEREQIG RFMQLVVEHK HKIGFQGTLL IEPKPQEPTK HQYDYDASTV 250
YGFLKQFGLE KEIKLNIEAN HATLAGHTFH HEIATAIALG LFGSVDANRG 300
DPQLGWDTDQ FPNSVEENAL VMYEILKAGG FTTGGLNFDA KVRRQSTDKY 350
DLFYGHIGAM DTMALALKVA ARMIEDGELD KRVARRYAGW NGELGQQILK 400
GQMNLADIAQ YATQHNLAPE HQSGHQELLE NVVNRYLFDR 440
Length:440
Mass (Da):49,837
Last modified:October 3, 2012 - v1
Checksum:i7E3EB4FEF8D938AD
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003683 Genomic DNA. Translation: AFN34687.1.
RefSeqiWP_014227204.1. NC_018106.1.
YP_006501256.1. NC_018106.1.

Genome annotation databases

EnsemblBacteriaiAFN34687; AFN34687; A225_5595.
GeneIDi13310100.
KEGGikoe:A225_5595.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003683 Genomic DNA. Translation: AFN34687.1 .
RefSeqi WP_014227204.1. NC_018106.1.
YP_006501256.1. NC_018106.1.

3D structure databases

ProteinModelPortali I6W118.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFN34687 ; AFN34687 ; A225_5595 .
GeneIDi 13310100.
KEGGi koe:A225_5595.

Phylogenomic databases

KOi K01805.

Enzyme and pathway databases

BioCyci KOXY1191061:GLEY-5595-MONOMER.

Family and domain databases

Gene3Di 3.20.20.150. 1 hit.
HAMAPi MF_00455. Xylose_isom_A.
InterProi IPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view ]
Pfami PF01261. AP_endonuc_2. 1 hit.
[Graphical view ]
PRINTSi PR00688. XYLOSISMRASE.
SUPFAMi SSF51658. SSF51658. 1 hit.
TIGRFAMsi TIGR02630. xylose_isom_A. 1 hit.
PROSITEi PS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete Genome Sequence of Klebsiella oxytoca E718, a New Delhi Metallo-beta-Lactamase-1-Producing Nosocomial Strain."
    Liao T.L., Lin A.C., Chen E., Huang T.W., Liu Y.M., Chang Y.H., Lai J.F., Lauderdale T.L., Wang J.T., Chang S.C., Tsai S.F., Chen Y.T.
    J. Bacteriol. 194:5454-5454(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: E718Imported.

Entry informationi

Entry nameiI6W118_KLEOX
AccessioniPrimary (citable) accession number: I6W118
Entry historyi
Integrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: September 3, 2014
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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