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Protein
Submitted name:

4-aminobutyrate aminotransferase

Gene

PFC_01685

Organism
Pyrococcus furiosus COM1
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. 4-aminobutyrate transaminase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AminotransferaseImported, Transferase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciPFUR1185654:GLJ1-341-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
4-aminobutyrate aminotransferaseImported (EC:2.6.1.19Imported)
Gene namesi
ORF Names:PFC_01685Imported
OrganismiPyrococcus furiosus COM1Imported
Taxonomic identifieri1185654 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
ProteomesiUP000006216 Componenti: Chromosome

PTM / Processingi

Proteomic databases

PRIDEiI6UZZ1.

Structurei

3D structure databases

ProteinModelPortaliI6UZZ1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.UniRule annotation

Phylogenomic databases

KOiK00823.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

I6UZZ1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEYPKIITKL PGPKATEIIE RESRILSPGI GVKLFPLVPK RGFGALIEDV
60 70 80 90 100
DGNIFIDFLA GAAAASTGYS HPKLVKAVQE QVALIQHSMI GYTHNERAIR
110 120 130 140 150
VAEKLAKISP IKNPRIIFGM SGSDAVDMAI KVSKFSTRRP WILSFIGAYH
160 170 180 190 200
GQTLGATSIA AFQSSQKRGF SPLMPNVIWL PYPNPYRNIW GIDGYEEPNE
210 220 230 240 250
LINRFLDYLE NYVFSHLSPS DEVAALFAEP IQGDAGIVVP PENFFKEVQK
260 270 280 290 300
VLNDLGILLV MDEVQTGIGR TGKWFASEWF SVEPDLIIFG KGVASGMGLS
310 320 330 340 350
GVIGRKELMD LTSGAALLTP AANPVVSAAA EATLEIIEEE NLLENALKVG
360 370 380 390 400
NFIKKRLEEM KEVFEVIGDV RGKGLMIGVE IVKDRESKKP DPELTGKICW
410 420 430 440 450
RAFELGLILP SYGMFQNVIR ITPPLVITQE IAEKGLEIME RAIKDALAGK

VERKVVTWH
Length:459
Mass (Da):50,555
Last modified:October 3, 2012 - v1
Checksum:i4B7BD1DAE13D7DA0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003685 Genomic DNA. Translation: AFN03308.1.
RefSeqiYP_006491600.1. NC_018092.1.

Genome annotation databases

EnsemblBacteriaiAFN03308; AFN03308; PFC_01685.
GeneIDi13302325.
KEGGipfi:PFC_01685.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003685 Genomic DNA. Translation: AFN03308.1.
RefSeqiYP_006491600.1. NC_018092.1.

3D structure databases

ProteinModelPortaliI6UZZ1.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiI6UZZ1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFN03308; AFN03308; PFC_01685.
GeneIDi13302325.
KEGGipfi:PFC_01685.

Phylogenomic databases

KOiK00823.

Enzyme and pathway databases

BioCyciPFUR1185654:GLJ1-341-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome Sequencing of a Genetically-Tractable Pyrococcus furiosus Strain Reveals a Highly Dynamic Genome."
    Bridger S.L., Lancaster W.A., Poole F.L.II., Schut G.J., Adams M.W.
    J. Bacteriol. 194:4097-4106(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: COM1Imported.

Entry informationi

Entry nameiI6UZZ1_9EURY
AccessioniPrimary (citable) accession number: I6UZZ1
Entry historyi
Integrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: April 29, 2015
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.