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I6URY1 (I6URY1_9EURY) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 14. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Glyceraldehyde-3-phosphate dehydrogenase HAMAP-Rule MF_00559

Short name=GAPDH HAMAP-Rule MF_00559
EC=1.2.1.59 HAMAP-Rule MF_00559
Alternative name(s):
NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase HAMAP-Rule MF_00559
Gene names
Name:gap HAMAP-Rule MF_00559
ORF Names:PFC_09215 EMBL AFN04766.1
OrganismPyrococcus furiosus COM1 [Complete proteome] EMBL AFN04766.1
Taxonomic identifier1185654 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus

Protein attributes

Sequence length334 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding12 – 132NAD By similarity HAMAP-Rule MF_00559
Region140 – 1423Glyceraldehyde 3-phosphate binding By similarity HAMAP-Rule MF_00559
Region192 – 1932Glyceraldehyde 3-phosphate binding By similarity HAMAP-Rule MF_00559

Sites

Active site1411Nucleophile By similarity HAMAP-Rule MF_00559 PIRSR PIRSR000149-1
Binding site1111NAD; via amide nitrogen By similarity HAMAP-Rule MF_00559
Binding site1671NAD By similarity HAMAP-Rule MF_00559
Binding site2981NAD; via carbonyl oxygen By similarity HAMAP-Rule MF_00559

Sequences

Sequence LengthMass (Da)Tools
I6URY1 [UniParc].

Last modified October 3, 2012. Version 1.
Checksum: 224E0626923AFC66

FASTA33437,436
        10         20         30         40         50         60 
MKIKVGINGY GTIGKRVAYA VTKQDDMELI GVTKTKPDFE AYRAKELGIP VYAASEEFLP 

        70         80         90        100        110        120 
RFEKAGFEVE GTLNDLLEKV DIIVDATPGG MGEKNKQLYE KAGVKAIFQG GEKAEVAQVS 

       130        140        150        160        170        180 
FVAQANYEAA LGKDYVRVVS CNTTGLVRTL NAIKDYVDYV YAVMIRRAAD PNDIKRGPIN 

       190        200        210        220        230        240 
AIKPSVTIPS HHGPDVQTVI PINIETSAFV VPTTIMHVHS IMVELKKPLT REDVIDIFEN 

       250        260        270        280        290        300 
TTRVLLFEKE KGFESTAQLI EFARDLHREW NNLYEIAVWK ESINVKGNRL FYIQAVHQES 

       310        320        330 
DVIPENIDAI RAMFEIAEKW ESIKKTNKSL GILK 

« Hide

References

[1]"Genome Sequencing of a Genetically Tractable Pyrococcus furiosus Strain Reveals a Highly Dynamic Genome."
Bridger S.L., Lancaster W.A., Poole F.L.II., Schut G.J., Adams M.W.
J. Bacteriol. 194:4097-4106(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: COM1 EMBL AFN04766.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003685 Genomic DNA. Translation: AFN04766.1.
RefSeqYP_006493058.1. NC_018092.1.

3D structure databases

ProteinModelPortalI6URY1.
SMRI6URY1. Positions 1-334.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFN04766; AFN04766; PFC_09215.
GeneID13301306.
KEGGpfi:PFC_09215.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00150.

Enzyme and pathway databases

BioCycPFUR1185654:GLJ1-1833-MONOMER.
UniPathwayUPA00109; UER00184.

Family and domain databases

Gene3D3.40.50.720. 1 hit.
HAMAPMF_00559. G3P_dehdrog_arch.
InterProIPR020831. GlycerAld/Erythrose_P_DH.
IPR020830. GlycerAld_3-P_DH_AS.
IPR020829. GlycerAld_3-P_DH_cat.
IPR020828. GlycerAld_3-P_DH_NAD(P)-bd.
IPR006436. Glyceraldehyde-3-P_DH_2_arc.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamPF02800. Gp_dh_C. 1 hit.
PF00044. Gp_dh_N. 1 hit.
[Graphical view]
PIRSFPIRSF000149. GAP_DH. 1 hit.
SMARTSM00846. Gp_dh_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR01546. GAPDH-II_archae. 1 hit.
PROSITEPS00071. GAPDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameI6URY1_9EURY
AccessionPrimary (citable) accession number: I6URY1
Entry history
Integrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: June 11, 2014
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)