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I6URR3

- I6URR3_9EURY

UniProt

I6URR3 - I6URR3_9EURY

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Protein

Phosphoenolpyruvate carboxylase

Gene

ppcA

Organism
Pyrococcus furiosus COM1
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Note: Magnesium.UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationImported

Keywords - Biological processi

Carbon dioxide fixationUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotation, PyruvateImported

Enzyme and pathway databases

BioCyciPFUR1185654:GLJ1-1732-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcAUniRule annotation
ORF Names:PFC_08705Imported
OrganismiPyrococcus furiosus COM1Imported
Taxonomic identifieri1185654 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
ProteomesiUP000006216: Chromosome

PTM / Processingi

Proteomic databases

PRIDEiI6URR3.

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliI6URR3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 2 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_01904. PEPcase_type2.
InterProiIPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF14010. PEPcase_2. 1 hit.
[Graphical view]
PIRSFiPIRSF006677. UCP006677. 1 hit.
SUPFAMiSSF51621. SSF51621. 1 hit.
TIGRFAMsiTIGR02751. PEPCase_arch. 1 hit.

Sequencei

Sequence statusi: Complete.

I6URR3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIPRIMSTQH PDNYSIPFFA SSPILEGEDE ITEAFYAFSV LGADEQMWDF
60 70 80 90 100
EGKEVDEFVV KKLLERYPTF FKNNILGKDI RLTPRVPNPS VEKEEAKLLL
110 120 130 140 150
ETLQGIARSA DYARIFYGDN IAPIFEVILP MTTSVEEIER VYWLYKKAVV
160 170 180 190 200
WISREKIYDI TVREWIGDFF PEKINVIPLF ETKSALIKAA KITEAYILNR
210 220 230 240 250
KNDIEYQRVF FARSDPAMNY GLITAVTYVK RALYEVLKVE EELSIPIYPI
260 270 280 290 300
IGVGGPPLRG GMRPDNVDAV VKEYPSVQTF TIQSSFKYDY PTKDVVKAVE
310 320 330 340 350
KIKSTKRKLP IPVEIPPFLV NYEAEYQKQI RILAPYINSV AKRIPRRRKR
360 370 380 390 400
KLHIGLFGYS RNVNGITLPR AITFTAALYS IGIPPELLAL NSLTDSQLET
410 420 430 440 450
ISEYYINVYE DLEFAMRFFS PKVAEKVGLK ELAERVKEFK PEQIPEYIEE
460 470
AEIVFKGEGD VMKLAQLRGF LG
Length:472
Mass (Da):54,315
Last modified:October 3, 2012 - v1
Checksum:i430BB52B442C6897
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003685 Genomic DNA. Translation: AFN04666.1.
RefSeqiWP_011013117.1. NC_018092.1.
YP_006492958.1. NC_018092.1.

Genome annotation databases

EnsemblBacteriaiAFN04666; AFN04666; PFC_08705.
GeneIDi13301205.
KEGGipfi:PFC_08705.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003685 Genomic DNA. Translation: AFN04666.1 .
RefSeqi WP_011013117.1. NC_018092.1.
YP_006492958.1. NC_018092.1.

3D structure databases

ProteinModelPortali I6URR3.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi I6URR3.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFN04666 ; AFN04666 ; PFC_08705 .
GeneIDi 13301205.
KEGGi pfi:PFC_08705.

Phylogenomic databases

KOi K01595.

Enzyme and pathway databases

BioCyci PFUR1185654:GLJ1-1732-MONOMER.

Family and domain databases

HAMAPi MF_01904. PEPcase_type2.
InterProi IPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF14010. PEPcase_2. 1 hit.
[Graphical view ]
PIRSFi PIRSF006677. UCP006677. 1 hit.
SUPFAMi SSF51621. SSF51621. 1 hit.
TIGRFAMsi TIGR02751. PEPCase_arch. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genome Sequencing of a Genetically-Tractable Pyrococcus furiosus Strain Reveals a Highly Dynamic Genome."
    Bridger S.L., Lancaster W.A., Poole F.L.II., Schut G.J., Adams M.W.
    J. Bacteriol. 194:4097-4106(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: COM1Imported.

Entry informationi

Entry nameiI6URR3_9EURY
AccessioniPrimary (citable) accession number: I6URR3
Entry historyi
Integrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: November 26, 2014
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3