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Protein

Phosphoenolpyruvate carboxylase

Gene

ppcA

Organism
Pyrococcus furiosus COM1
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationImported
Biological processCarbon dioxide fixationUniRule annotation
LigandMagnesiumUniRule annotation, PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcAUniRule annotation
ORF Names:PFC_08705Imported
OrganismiPyrococcus furiosus COM1Imported
Taxonomic identifieri1185654 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi
  • UP000006216 Componenti: Chromosome

PTM / Processingi

Proteomic databases

PRIDEiI6URR3

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliI6URR3
SMRiI6URR3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 2 family.UniRule annotation

Phylogenomic databases

KOiK01595
OrthoDBiPOG093Z01LI

Family and domain databases

HAMAPiMF_01904 PEPcase_type2, 1 hit
InterProiView protein in InterPro
IPR007566 PEP_COase_arc-type
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
PfamiView protein in Pfam
PF14010 PEPcase_2, 1 hit
PIRSFiPIRSF006677 UCP006677, 1 hit
SUPFAMiSSF51621 SSF51621, 1 hit
TIGRFAMsiTIGR02751 PEPCase_arch, 1 hit

Sequencei

Sequence statusi: Complete.

I6URR3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIPRIMSTQH PDNYSIPFFA SSPILEGEDE ITEAFYAFSV LGADEQMWDF
60 70 80 90 100
EGKEVDEFVV KKLLERYPTF FKNNILGKDI RLTPRVPNPS VEKEEAKLLL
110 120 130 140 150
ETLQGIARSA DYARIFYGDN IAPIFEVILP MTTSVEEIER VYWLYKKAVV
160 170 180 190 200
WISREKIYDI TVREWIGDFF PEKINVIPLF ETKSALIKAA KITEAYILNR
210 220 230 240 250
KNDIEYQRVF FARSDPAMNY GLITAVTYVK RALYEVLKVE EELSIPIYPI
260 270 280 290 300
IGVGGPPLRG GMRPDNVDAV VKEYPSVQTF TIQSSFKYDY PTKDVVKAVE
310 320 330 340 350
KIKSTKRKLP IPVEIPPFLV NYEAEYQKQI RILAPYINSV AKRIPRRRKR
360 370 380 390 400
KLHIGLFGYS RNVNGITLPR AITFTAALYS IGIPPELLAL NSLTDSQLET
410 420 430 440 450
ISEYYINVYE DLEFAMRFFS PKVAEKVGLK ELAERVKEFK PEQIPEYIEE
460 470
AEIVFKGEGD VMKLAQLRGF LG
Length:472
Mass (Da):54,315
Last modified:October 3, 2012 - v1
Checksum:i430BB52B442C6897
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003685 Genomic DNA Translation: AFN04666.1
RefSeqiWP_011013117.1, NC_018092.1

Genome annotation databases

EnsemblBacteriaiAFN04666; AFN04666; PFC_08705
GeneIDi1469857
KEGGipfi:PFC_08705
PATRICifig|1185654.4.peg.1770

Similar proteinsi

Entry informationi

Entry nameiI6URR3_9EURY
AccessioniPrimary (citable) accession number: I6URR3
Entry historyiIntegrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: May 23, 2018
This is version 31 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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