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I6URR3 (I6URR3_9EURY) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 12. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase HAMAP-Rule MF_01904

Short name=PEPC HAMAP-Rule MF_01904
Short name=PEPCase HAMAP-Rule MF_01904
EC=4.1.1.31 HAMAP-Rule MF_01904
Gene names
Name:ppcA HAMAP-Rule MF_01904
ORF Names:PFC_08705 EMBL AFN04666.1
OrganismPyrococcus furiosus COM1 [Complete proteome] EMBL AFN04666.1
Taxonomic identifier1185654 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus

Protein attributes

Sequence length472 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_01904

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_01904

Cofactor

Magnesium By similarity. HAMAP-Rule MF_01904

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_01904

Sequence similarities

Belongs to the PEPCase type 2 family. HAMAP-Rule MF_01904

Sequences

Sequence LengthMass (Da)Tools
I6URR3 [UniParc].

Last modified October 3, 2012. Version 1.
Checksum: 430BB52B442C6897

FASTA47254,315
        10         20         30         40         50         60 
MIPRIMSTQH PDNYSIPFFA SSPILEGEDE ITEAFYAFSV LGADEQMWDF EGKEVDEFVV 

        70         80         90        100        110        120 
KKLLERYPTF FKNNILGKDI RLTPRVPNPS VEKEEAKLLL ETLQGIARSA DYARIFYGDN 

       130        140        150        160        170        180 
IAPIFEVILP MTTSVEEIER VYWLYKKAVV WISREKIYDI TVREWIGDFF PEKINVIPLF 

       190        200        210        220        230        240 
ETKSALIKAA KITEAYILNR KNDIEYQRVF FARSDPAMNY GLITAVTYVK RALYEVLKVE 

       250        260        270        280        290        300 
EELSIPIYPI IGVGGPPLRG GMRPDNVDAV VKEYPSVQTF TIQSSFKYDY PTKDVVKAVE 

       310        320        330        340        350        360 
KIKSTKRKLP IPVEIPPFLV NYEAEYQKQI RILAPYINSV AKRIPRRRKR KLHIGLFGYS 

       370        380        390        400        410        420 
RNVNGITLPR AITFTAALYS IGIPPELLAL NSLTDSQLET ISEYYINVYE DLEFAMRFFS 

       430        440        450        460        470 
PKVAEKVGLK ELAERVKEFK PEQIPEYIEE AEIVFKGEGD VMKLAQLRGF LG 

« Hide

References

[1]"Genome Sequencing of a Genetically Tractable Pyrococcus furiosus Strain Reveals a Highly Dynamic Genome."
Bridger S.L., Lancaster W.A., Poole F.L.II., Schut G.J., Adams M.W.
J. Bacteriol. 194:4097-4106(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: COM1 EMBL AFN04666.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003685 Genomic DNA. Translation: AFN04666.1.
RefSeqYP_006492958.1. NC_018092.1.

3D structure databases

ProteinModelPortalI6URR3.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEI6URR3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFN04666; AFN04666; PFC_08705.
GeneID13301205.
KEGGpfi:PFC_08705.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01595.

Enzyme and pathway databases

BioCycPFUR1185654:GLJ1-1732-MONOMER.

Family and domain databases

HAMAPMF_01904. PEPcase_type2.
InterProIPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamPF14010. PEPcase_2. 1 hit.
[Graphical view]
PIRSFPIRSF006677. UCP006677. 1 hit.
SUPFAMSSF51621. SSF51621. 1 hit.
TIGRFAMsTIGR02751. PEPCase_arch. 1 hit.
ProtoNetSearch...

Entry information

Entry nameI6URR3_9EURY
AccessionPrimary (citable) accession number: I6URR3
Entry history
Integrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: April 16, 2014
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)