Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

I6THZ2

- I6THZ2_ENCHA

UniProt

I6THZ2 - I6THZ2_ENCHA

Protein

DNA ligase

Gene

EHEL_021150

Organism
Encephalitozoon hellem (strain ATCC 50504) (Microsporidian parasite)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 12 (01 Oct 2014)
      Sequence version 1 (03 Oct 2012)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. DNA binding Source: InterPro
    3. DNA ligase (ATP) activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA ligation involved in DNA repair Source: InterPro
    2. DNA recombination Source: UniProtKB-KW
    3. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseUniRule annotationImported

    Keywords - Biological processi

    DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
    Gene namesi
    Ordered Locus Names:EHEL_021150Imported
    OrganismiEncephalitozoon hellem (strain ATCC 50504) (Microsporidian parasite)Imported
    Taxonomic identifieri907965 [NCBI]
    Taxonomic lineageiEukaryotaFungiMicrosporidiaUnikaryonidaeEncephalitozoon
    ProteomesiUP000010086: Chromosome II

    Organism-specific databases

    EuPathDBiMicrosporidiaDB:EHEL_021150.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ATP-dependent DNA ligase family.UniRule annotation

    Phylogenomic databases

    KOiK10747.
    OrthoDBiEOG7TXKRG.

    Family and domain databases

    Gene3Di1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProiIPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view]
    PfamiPF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsiTIGR00574. dnl1. 1 hit.
    PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    I6THZ2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSKILFSDFC ATLEKINLTT KRLEIQSILT DYLKEVCKTH PQSLAPALYL    50
    STGMVYPEYF NKELGVGENM LVSVVAEFTG KSIKNIRSEY SKVGDLGTIA 100
    MKCRVSQLFI PKTQLEVMDV FLGMRRIVGE EGPKSSSSKK RIILGMMVKC 150
    SPLESKYLVR LIEGRLKIGL ALKTVLISLG NVFSSDKADE IKAAFNRQPD 200
    IGRLAECILD HGMENLAVRF QVTPGIPLKP MLANPSKDLT SAFKRVENKS 250
    FACEYKYDGE RVQIHKFGSS IETFSRNSEK TTEKYPDLMD LYNISDKDFI 300
    IDGEIVAYDR REGKILPFQV LTTRKRKRVE SSKIDVHVCV FAFDLIYFDG 350
    KAYIDEVLEE RRRVLHSSFR EVEGRFQFAE FRDCETPEDA ETFFSTSVEK 400
    GFEGIMVKTL GPDTTYLPSQ RSNKWIKIKK DYLESMSDSL DLVVMGAYYG 450
    KGKRTGFYGG FLLGVYNDEE EKFEALCKIG TGFDDSILSK LYEQLSSNLC 500
    SAPKNYSYKE SVKPDVWVEA KYVWEVRAAG MSLSPIYNAG GSRNGKGISL 550
    RFPRFIRERD DKGVKEATTS SQVYQMYLDS KVENSEEFY 589
    Length:589
    Mass (Da):66,940
    Last modified:October 3, 2012 - v1
    Checksum:iBABF72922935368E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002714 Genomic DNA. Translation: AFM97869.1.
    RefSeqiXP_003886850.1. XM_003886801.1.

    Genome annotation databases

    GeneIDi13467568.
    KEGGiehe:EHEL_021150.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002714 Genomic DNA. Translation: AFM97869.1 .
    RefSeqi XP_003886850.1. XM_003886801.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 13467568.
    KEGGi ehe:EHEL_021150.

    Organism-specific databases

    EuPathDBi MicrosporidiaDB:EHEL_021150.

    Phylogenomic databases

    KOi K10747.
    OrthoDBi EOG7TXKRG.

    Family and domain databases

    Gene3Di 1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProi IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view ]
    Pfami PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsi TIGR00574. dnl1. 1 hit.
    PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Gain and loss of multiple functionally related, horizontally transferred genes in the reduced genomes of two microsporidian parasites."
      Pombert J.-F., Selman M., Burki F., Bardell F.T., Farinelli L., Solter L.F., Whitman D.W., Weiss L.M., Corradi N., Keeling P.J.
      Proc. Natl. Acad. Sci. U.S.A. 109:12638-12643(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 50504Imported.

    Entry informationi

    Entry nameiI6THZ2_ENCHA
    AccessioniPrimary (citable) accession number: I6THZ2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 3, 2012
    Last sequence update: October 3, 2012
    Last modified: October 1, 2014
    This is version 12 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3