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I6THZ2 (I6THZ2_ENCHA) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 11. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein attributes

Sequence length589 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).

Sequence similarities

Belongs to the ATP-dependent DNA ligase family. RuleBase RU004196

Sequences

Sequence LengthMass (Da)Tools
I6THZ2 [UniParc].

Last modified October 3, 2012. Version 1.
Checksum: BABF72922935368E

FASTA58966,940
        10         20         30         40         50         60 
MSKILFSDFC ATLEKINLTT KRLEIQSILT DYLKEVCKTH PQSLAPALYL STGMVYPEYF 

        70         80         90        100        110        120 
NKELGVGENM LVSVVAEFTG KSIKNIRSEY SKVGDLGTIA MKCRVSQLFI PKTQLEVMDV 

       130        140        150        160        170        180 
FLGMRRIVGE EGPKSSSSKK RIILGMMVKC SPLESKYLVR LIEGRLKIGL ALKTVLISLG 

       190        200        210        220        230        240 
NVFSSDKADE IKAAFNRQPD IGRLAECILD HGMENLAVRF QVTPGIPLKP MLANPSKDLT 

       250        260        270        280        290        300 
SAFKRVENKS FACEYKYDGE RVQIHKFGSS IETFSRNSEK TTEKYPDLMD LYNISDKDFI 

       310        320        330        340        350        360 
IDGEIVAYDR REGKILPFQV LTTRKRKRVE SSKIDVHVCV FAFDLIYFDG KAYIDEVLEE 

       370        380        390        400        410        420 
RRRVLHSSFR EVEGRFQFAE FRDCETPEDA ETFFSTSVEK GFEGIMVKTL GPDTTYLPSQ 

       430        440        450        460        470        480 
RSNKWIKIKK DYLESMSDSL DLVVMGAYYG KGKRTGFYGG FLLGVYNDEE EKFEALCKIG 

       490        500        510        520        530        540 
TGFDDSILSK LYEQLSSNLC SAPKNYSYKE SVKPDVWVEA KYVWEVRAAG MSLSPIYNAG 

       550        560        570        580 
GSRNGKGISL RFPRFIRERD DKGVKEATTS SQVYQMYLDS KVENSEEFY 

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References

[1]"Gain and loss of multiple functionally related, horizontally transferred genes in the reduced genomes of two microsporidian parasites."
Pombert J.-F., Selman M., Burki F., Bardell F.T., Farinelli L., Solter L.F., Whitman D.W., Weiss L.M., Corradi N., Keeling P.J.
Proc. Natl. Acad. Sci. U.S.A. 109:12638-12643(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 50504 EMBL AFM97869.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002714 Genomic DNA. Translation: AFM97869.1.
RefSeqXP_003886850.1. XM_003886801.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID13467568.
KEGGehe:EHEL_021150.

Organism-specific databases

EuPathDBMicrosporidiaDB:EHEL_021150.

Phylogenomic databases

KOK10747.
OrthoDBEOG7TXKRG.

Family and domain databases

Gene3D1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsTIGR00574. dnl1. 1 hit.
PROSITEPS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameI6THZ2_ENCHA
AccessionPrimary (citable) accession number: I6THZ2
Entry history
Integrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: April 16, 2014
This is version 11 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)