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I6S0A4 (I6S0A4_ENTCL) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 13. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length359 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. SAAS SAAS009006 HAMAP-Rule MF_01201

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. RuleBase RU004188 HAMAP-Rule MF_01201

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site341Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2551Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1291Substrate By similarity HAMAP-Rule MF_01201
Binding site3031Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue341N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
I6S0A4 [UniParc].

Last modified October 3, 2012. Version 1.
Checksum: 3015C8ADA61278A8

FASTA35939,228
        10         20         30         40         50         60 
MQAATVVINR RALRHNLQRL RELAPASKLV AVVKANAYGH GLLETARTLP DADAFGVARL 

        70         80         90        100        110        120 
EEALRLRAGG IAQPILLLEG FFEAADLPTI ADQHLHTAVH NEEQLSALET AELSEPVTVW 

       130        140        150        160        170        180 
MKLDTGMHRL GVRPENAQAF YQRLCQCKNV RQPVNIVSHF ARADEPDCGA TEQQLDIFNT 

       190        200        210        220        230        240 
FCEGKPGMRS IAASGGILLW PQSHFDWARP GIILYGVSPL ENRPWGPDFG FQPVMSLVSK 

       250        260        270        280        290        300 
LIAVREHKAG EPVGYGGTWT SERDTRLGVV AMGYGDGYPR AAPSGTPVLV NGREVTIVGR 

       310        320        330        340        350 
VAMDMICVDL GPDAQDKAGD DVVMWGDGLP VERIAEITKV SAYELITRLT SRVAMKYID 

« Hide

References

[1]"Genome sequence of Enterobacter cloacae subsp. dissolvens SDM, an efficient biomass-utilizing producer of platform chemical 2,3-butanediol."
Xu Y., Wang A., Tao F., Su F., Tang H., Ma C., Xu P.
J. Bacteriol. 194:897-898(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SDM EMBL AFM58059.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003678 Genomic DNA. Translation: AFM58059.1.
RefSeqYP_006475761.1. NC_018079.1.

3D structure databases

ProteinModelPortalI6S0A4.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFM58059; AFM58059; A3UG_01530.
GeneID13168717.
KEGGenl:A3UG_01530.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01775.

Enzyme and pathway databases

UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameI6S0A4_ENTCL
AccessionPrimary (citable) accession number: I6S0A4
Entry history
Integrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: February 19, 2014
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)