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Protein
Submitted name:

MHC class I antigen

Gene

Tube-W25

Organism
Tupaia belangeri (Common tree shrew) (Tupaia glis belangeri)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Involved in the presentation of foreign antigens to the immune system.SAAS annotation

GO - Biological processi

Keywordsi

Biological processImmunity

Names & Taxonomyi

Protein namesi
Submitted name:
MHC class I antigenImported
Gene namesi
Name:Tube-W25Imported
OrganismiTupaia belangeri (Common tree shrew) (Tupaia glis belangeri)Imported
Taxonomic identifieri37347 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresScandentiaTupaiidaeTupaia

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei273 – 296HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane, MHC ISAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_500370579322 – 328Sequence analysisAdd BLAST307

Keywords - PTMi

Disulfide bondSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliI6RSZ1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini200 – 260IGc1InterPro annotationAdd BLAST61

Sequence similaritiesi

Belongs to the MHC class I family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
3.30.500.10. 1 hit.
InterProiView protein in InterPro
IPR036179. Ig-like_dom_sf.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR011161. MHC_I-like_Ag-recog.
IPR037055. MHC_I-like_Ag-recog_sf.
IPR011162. MHC_I/II-like_Ag-recog.
IPR001039. MHC_I_a_a1/a2.
IPR010579. MHC_I_a_C.
PfamiView protein in Pfam
PF07654. C1-set. 1 hit.
PF00129. MHC_I. 1 hit.
PF06623. MHC_I_C. 1 hit.
PRINTSiPR01638. MHCCLASSI.
SMARTiView protein in SMART
SM00407. IGc1. 1 hit.
SUPFAMiSSF48726. SSF48726. 1 hit.
SSF54452. SSF54452. 1 hit.
PROSITEiView protein in PROSITE
PS00290. IG_MHC. 1 hit.

Sequencei

Sequence statusi: Complete.

I6RSZ1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPRTLLLVL SGLLALTETW AGSHSMRYFD TVVSRSGGEP RYIEVGYVDD
60 70 80 90 100
TQFVRFDSDS ASQREEPRAP WMDKVDPEYW DRNTRRAKDN AQTYRLSLQT
110 120 130 140 150
LLAYYNLSEA GSHTFQSMYG CEVGSDGRLL RGYRQYAFNG RDYIALNEDL
160 170 180 190 200
RSWTAADKVA QLTQRKWEAA GGAELRRAYL EEECVQWLGI YLENGKEMLQ
210 220 230 240 250
RTEISLTWQR DGEDQTQDME LVETRPAGDG TFQKWAAVVV PSGEEQRYTC
260 270 280 290 300
HVQHEGLPEP LTLRWEPHPQ SPLLIVGIVA GLVLLGVLVT GAIVIWRRSS
310 320
GGKKGHYAQT ARSDSAQGSD VSLTAPKV
Length:328
Mass (Da):36,972
Last modified:October 3, 2012 - v1
Checksum:iDAB4462C0C7688EA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JQ353676 mRNA. Translation: AFM54603.1.

Similar proteinsi

Entry informationi

Entry nameiI6RSZ1_TUPBE
AccessioniPrimary (citable) accession number: I6RSZ1
Entry historyiIntegrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: February 28, 2018
This is version 27 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)