SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

I6RL17

- I6RL17_ENTCL

UniProt

I6RL17 - I6RL17_ENTCL

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Thymidine kinase

Gene
tdk, A3UG_13010
Organism
Enterobacter cloacae subsp. dissolvens SDM
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei88 – 881Proton acceptor By similarityUniRule annotation
Metal bindingi145 – 1451Zinc By similarityUniRule annotation
Metal bindingi147 – 1471Zinc By similarityUniRule annotation
Metal bindingi182 – 1821Zinc By similarityUniRule annotation
Metal bindingi185 – 1851Zinc By similarityUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi9 – 168ATP By similarityUniRule annotation
Nucleotide bindingi87 – 904ATP By similarityUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. thymidine kinase activity Source: UniProtKB-HAMAP
  3. zinc ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotationsImported, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotationSAAS annotations

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotations, Metal-bindingUniRule annotationSAAS annotations, Nucleotide-binding, ZincUniRule annotationSAAS annotations

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkUniRule annotation
ORF Names:A3UG_13010Imported
OrganismiEnterobacter cloacae subsp. dissolvens SDMImported
Taxonomic identifieri1104326 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEnterobacterEnterobacter cloacae complex
ProteomesiUP000002891: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotationSAAS annotations

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotations

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotationSAAS annotations

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK00857.

Family and domain databases

HAMAPiMF_00124. Thymidine_kinase.
InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

I6RL17-1 [UniParc]FASTAAdd to Basket

« Hide

MAQLYFYYSA MNAGKSTALL QSSYNYQERG MRTVVYTAEI DDRFGAGKVS    50
SRIGLSSPAR LFNPQTDLLQ DIRAEHTSQP IHCVLVDESQ FLTREQVHAL 100
SEVVDELDIP VLCYGLRTDF RGELFAGSQY LLAWSDKLVE LKTICFCGRK 150
ASMVLRLDQA GKPYADGEQV VIGGNERYVS VCRKHYKEAL SVGSLTAIQH 200
DNRK 204
Length:204
Mass (Da):22,927
Last modified:October 3, 2012 - v1
Checksum:i6C76E0F9CB180439
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003678 Genomic DNA. Translation: AFM60330.1.
RefSeqiYP_006478032.1. NC_018079.1.

Genome annotation databases

EnsemblBacteriaiAFM60330; AFM60330; A3UG_13010.
GeneIDi13165731.
KEGGienl:A3UG_13010.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003678 Genomic DNA. Translation: AFM60330.1 .
RefSeqi YP_006478032.1. NC_018079.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFM60330 ; AFM60330 ; A3UG_13010 .
GeneIDi 13165731.
KEGGi enl:A3UG_13010.

Phylogenomic databases

KOi K00857.

Family and domain databases

HAMAPi MF_00124. Thymidine_kinase.
InterProi IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view ]
PANTHERi PTHR11441. PTHR11441. 1 hit.
Pfami PF00265. TK. 1 hit.
[Graphical view ]
PIRSFi PIRSF035805. TK_cell. 1 hit.
SUPFAMi SSF52540. SSF52540. 1 hit.
PROSITEi PS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of Enterobacter cloacae subsp. dissolvens SDM, an efficient biomass-utilizing producer of platform chemical 2,3-butanediol."
    Xu Y., Wang A., Tao F., Su F., Tang H., Ma C., Xu P.
    J. Bacteriol. 194:897-898(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SDMImported.

Entry informationi

Entry nameiI6RL17_ENTCL
AccessioniPrimary (citable) accession number: I6RL17
Entry historyi
Integrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: June 11, 2014
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi