I6R3J8 (I6R3J8_MYCTU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
ATP dependent DNA ligase EMBL AFM50442.1

Gene names

ORF Names:

TBXG_003031 EMBL AFM50442.1

Organism

Mycobacterium tuberculosis KZN 605 EMBL AFM50442.1

Taxonomic identifier

478435 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex › Mycobacterium tuberculosis

Protein attributes

Sequence length	759 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Ligase EMBL AFM50442.1
Gene Ontology (GO)
Biological_process	DNA recombination Inferred from electronic annotation. Source: InterPro DNA repair Inferred from electronic annotation. Source: InterPro
Molecular_function	ATP binding Inferred from electronic annotation. Source: InterPro DNA ligase (ATP) activity Inferred from electronic annotation. Source: InterPro DNA primase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	I6R3J8 [UniParc]. Last modified October 3, 2012. Version 1. Checksum: 8E1B59E06A356B3D	FASTA	759	83,625
	10 20 30 40 50 60 MGSASEQRVT LTNADKVLYP ATGTTKSDIF DYYAGVAEVM LGHIAGRPAT RKRWPNGVDQ 70 80 90 100 110 120 PAFFEKQLAL SAPPWLSRAT VAHRSGTTTY PIIDSATGLA WIAQQAALEV HVPQWRFVAE 130 140 150 160 170 180 PGSGELNPGP ATRLVFDLDP GEGVMMAQLA EVARAVRDLL ADIGLVTFPV TSGSKGLHLY 190 200 210 220 230 240 TPLDEPVSSR GATVLAKRVA QRLEQAMPAL VTSTMTKSLR AGKVFVDWSQ NSGSKTTIAP 250 260 270 280 290 300 YSLRGRTHPT VAAPRTWAEL DDPALRQLSY DEVLTRIARD GDLLERLDAD APVADRLTRY 310 320 330 340 350 360 RRMRDASKTP EPIPTAKPVT GDGNTFVIQE HHARRPHYDF RLERDGVLVS WAVPKNLPDN 370 380 390 400 410 420 TSVNHLAIHT EDHPLEYATF EGAIPSGEYG AGKVIIWDSG TYDTEKFHDD PHTGEVIVNL 430 440 450 460 470 480 HGGRISGRYA LIRTNGDRWL AHRLKNQKDQ KVFEFDNLAP MLATHGTVAG LKASQWAFEG 490 500 510 520 530 540 KWDGYRLLVE ADHGAVRLRS RSGRDVTAEY PQLRALAEDL ADHHVVLDGE AVVLDSSGVP 550 560 570 580 590 600 SFSQMQNRGR DTRVEFWAFD LLYLDGRALL GTRYQDRRKL LETLANATSL TVPELLPGDG 610 620 630 640 650 660 AQAFACSRKH GWEGVIAKRR DSRYQPGRRC ASWVKDKHWN TQEVVIGGWR AGEGGRSSGV 670 680 690 700 710 720 GSLLMGIPGP GGLQFAGRVG TGLSERELAN LKEMLAPLHT DESPFDVPLP ARDAKGITYV 730 740 750 KPALVAEVRY SEWTPEGRLR QSSWRGLRPD KKPSEVVRE

References

[1]

"The Genome Sequence of Mycobacterium tuberculosis strain KZN 605." The Broad Institute Genome Sequencing Platform, The Broad Institute Genome Sequencing Center for Infectious Disease. Galagan J., Murray M., Pillay M., Borowsky M.L., Young S.K., Zeng Q., Koehrsen M., Fitzgerald M., Abouelleil A., Alvarado L., Arachchi H.M., Berlin A.M., Borenstein D., Brown A., Chapman S.B., Chen Z., Dunbar C., Engels R. , Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E.R., Heiman D.I., Howarth C., Jen D., Larson L., Lui A., MacDonald J.P., Mehta T., Montmayeur A., Neiman D., Park D., Pearson M., Priest M., Richards J., Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S.N., Walk T., White J., Yandava C., Haas B., Nusbaum C., Birren B. Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: KZN 605 EMBL AFM50442.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001976 Genomic DNA. Translation: AFM50442.1.
RefSeq	YP_006474519.1. NC_018078.1.
3D structure databases
ProteinModelPortal	I6R3J8.
SMR	I6R3J8. Positions 2-289, 453-759.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AFM50442; AFM50442; TBXG_003031.
GeneID	13157426.
KEGG	mtz:TBXG_003031.
Phylogenomic databases
KO	K01971.
Family and domain databases
Gene3D	2.40.50.140. 1 hit.
InterPro	IPR012309. DNA_ligase_ATP-dep_C. IPR012310. DNA_ligase_ATP-dep_cent. IPR014146. DNA_pol_LigD_ligase_dom. IPR002755. DNA_primase_S. IPR014144. LigD_PE_domain. IPR014145. LigD_pol. IPR012340. NA-bd_OB-fold. [Graphical view]
Pfam	PF04679. DNA_ligase_A_C. 1 hit. PF01068. DNA_ligase_A_M. 1 hit. PF01896. DNA_primase_S. 1 hit. PF13298. LigD_N. 1 hit. [Graphical view]
SUPFAM	SSF50249. Nucleic_acid_OB. 1 hit.
TIGRFAMs	TIGR02777. LigD_PE_dom. 1 hit. TIGR02778. ligD_pol. 1 hit. TIGR02779. NHEJ_ligase_lig. 1 hit.
PROSITE	PS50160. DNA_LIGASE_A3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

I6R3J8_MYCTU

Accession

Primary (citable) accession number: I6R3J8

Entry history

Integrated into UniProtKB/TrEMBL:	October 3, 2012
Last sequence update:	October 3, 2012
Last modified:	May 1, 2013
This is version 8 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)