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I6R3J8

- I6R3J8_MYCTX

UniProt

I6R3J8 - I6R3J8_MYCTX

Protein
Submitted name:

ATP dependent DNA ligase

Gene

TBXG_003031

Organism
Mycobacterium tuberculosis KZN 605
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 15 (01 Oct 2014)
      Sequence version 1 (03 Oct 2012)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. ATP binding Source: InterPro
    2. DNA ligase (ATP) activity Source: InterPro
    3. DNA primase activity Source: InterPro

    GO - Biological processi

    1. DNA recombination Source: InterPro
    2. DNA repair Source: InterPro

    Keywords - Molecular functioni

    LigaseImported

    Enzyme and pathway databases

    BioCyciMTUB478435:GLGX-3127-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    ATP dependent DNA ligaseImported
    Gene namesi
    ORF Names:TBXG_003031Imported
    OrganismiMycobacterium tuberculosis KZN 605Imported
    Taxonomic identifieri478435 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
    ProteomesiUP000002898: Chromosome

    Structurei

    3D structure databases

    ProteinModelPortaliI6R3J8.
    SMRiI6R3J8. Positions 2-289, 453-759.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    KOiK01971.

    Family and domain databases

    Gene3Di2.40.50.140. 1 hit.
    InterProiIPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR014146. DNA_pol_LigD_ligase_dom.
    IPR002755. DNA_primase_S.
    IPR014144. LigD_PE_domain.
    IPR014145. LigD_pol.
    IPR012340. NA-bd_OB-fold.
    [Graphical view]
    PfamiPF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF01896. DNA_primase_S. 1 hit.
    PF13298. LigD_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF50249. SSF50249. 1 hit.
    TIGRFAMsiTIGR02777. LigD_PE_dom. 1 hit.
    TIGR02778. ligD_pol. 1 hit.
    TIGR02779. NHEJ_ligase_lig. 1 hit.
    PROSITEiPS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    I6R3J8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGSASEQRVT LTNADKVLYP ATGTTKSDIF DYYAGVAEVM LGHIAGRPAT    50
    RKRWPNGVDQ PAFFEKQLAL SAPPWLSRAT VAHRSGTTTY PIIDSATGLA 100
    WIAQQAALEV HVPQWRFVAE PGSGELNPGP ATRLVFDLDP GEGVMMAQLA 150
    EVARAVRDLL ADIGLVTFPV TSGSKGLHLY TPLDEPVSSR GATVLAKRVA 200
    QRLEQAMPAL VTSTMTKSLR AGKVFVDWSQ NSGSKTTIAP YSLRGRTHPT 250
    VAAPRTWAEL DDPALRQLSY DEVLTRIARD GDLLERLDAD APVADRLTRY 300
    RRMRDASKTP EPIPTAKPVT GDGNTFVIQE HHARRPHYDF RLERDGVLVS 350
    WAVPKNLPDN TSVNHLAIHT EDHPLEYATF EGAIPSGEYG AGKVIIWDSG 400
    TYDTEKFHDD PHTGEVIVNL HGGRISGRYA LIRTNGDRWL AHRLKNQKDQ 450
    KVFEFDNLAP MLATHGTVAG LKASQWAFEG KWDGYRLLVE ADHGAVRLRS 500
    RSGRDVTAEY PQLRALAEDL ADHHVVLDGE AVVLDSSGVP SFSQMQNRGR 550
    DTRVEFWAFD LLYLDGRALL GTRYQDRRKL LETLANATSL TVPELLPGDG 600
    AQAFACSRKH GWEGVIAKRR DSRYQPGRRC ASWVKDKHWN TQEVVIGGWR 650
    AGEGGRSSGV GSLLMGIPGP GGLQFAGRVG TGLSERELAN LKEMLAPLHT 700
    DESPFDVPLP ARDAKGITYV KPALVAEVRY SEWTPEGRLR QSSWRGLRPD 750
    KKPSEVVRE 759
    Length:759
    Mass (Da):83,625
    Last modified:October 3, 2012 - v1
    Checksum:i8E1B59E06A356B3D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001976 Genomic DNA. Translation: AFM50442.1.
    RefSeqiYP_006474519.1. NC_018078.1.

    Genome annotation databases

    EnsemblBacteriaiAFM50442; AFM50442; TBXG_003031.
    GeneIDi13157426.
    KEGGimtz:TBXG_003031.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001976 Genomic DNA. Translation: AFM50442.1 .
    RefSeqi YP_006474519.1. NC_018078.1.

    3D structure databases

    ProteinModelPortali I6R3J8.
    SMRi I6R3J8. Positions 2-289, 453-759.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AFM50442 ; AFM50442 ; TBXG_003031 .
    GeneIDi 13157426.
    KEGGi mtz:TBXG_003031.

    Phylogenomic databases

    KOi K01971.

    Enzyme and pathway databases

    BioCyci MTUB478435:GLGX-3127-MONOMER.

    Family and domain databases

    Gene3Di 2.40.50.140. 1 hit.
    InterProi IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR014146. DNA_pol_LigD_ligase_dom.
    IPR002755. DNA_primase_S.
    IPR014144. LigD_PE_domain.
    IPR014145. LigD_pol.
    IPR012340. NA-bd_OB-fold.
    [Graphical view ]
    Pfami PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF01896. DNA_primase_S. 1 hit.
    PF13298. LigD_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50249. SSF50249. 1 hit.
    TIGRFAMsi TIGR02777. LigD_PE_dom. 1 hit.
    TIGR02778. ligD_pol. 1 hit.
    TIGR02779. NHEJ_ligase_lig. 1 hit.
    PROSITEi PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The Genome Sequence of Mycobacterium tuberculosis strain KZN 605."
      The Broad Institute Genome Sequencing Platform, The Broad Institute Genome Sequencing Center for Infectious Disease.
      Galagan J., Murray M., Pillay M., Borowsky M.L., Young S.K., Zeng Q., Koehrsen M., Fitzgerald M., Abouelleil A., Alvarado L., Arachchi H.M., Berlin A.M., Borenstein D., Brown A., Chapman S.B., Chen Z., Dunbar C., Engels R.
      , Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E.R., Heiman D.I., Howarth C., Jen D., Larson L., Lui A., MacDonald J.P., Mehta T., Montmayeur A., Neiman D., Park D., Pearson M., Priest M., Richards J., Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S.N., Walk T., White J., Yandava C., Haas B., Nusbaum C., Birren B.
      Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: KZN 605Imported.

    Entry informationi

    Entry nameiI6R3J8_MYCTX
    AccessioniPrimary (citable) accession number: I6R3J8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 3, 2012
    Last sequence update: October 3, 2012
    Last modified: October 1, 2014
    This is version 15 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3