I5AMT5 (I5AMT5_DROPS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
GA13730, isoform B EMBL EIM52270.1
EC=1.2.4.2 EMBL EIM52270.1

Gene names

Name:	Dpse\GA13730 EMBL EIM52270.1
ORF Names:	Dpse_GA13730 EMBL EIM52270.1, GA13730 FlyBase FBgn0073766

Organism

Drosophila pseudoobscura pseudoobscura (Fruit fly) [Reference proteome] EMBL EIM52270.1

Taxonomic identifier

46245 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Eremoneura › Cyclorrhapha › Schizophora › Acalyptratae › Ephydroidea › Drosophilidae › Drosophilinae › Drosophilini › Drosophilina › Drosophiliti › Drosophila › Sophophora › obscura group › pseudoobscura subgroup › Drosophila pseudoobscura

Protein attributes

Sequence length	738 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Oxidoreductase EMBL EIM52270.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	tricarboxylic acid cycle Inferred from electronic annotation. Source: InterPro
Molecular_function	oxoglutarate dehydrogenase (succinyl-transferring) activity Inferred from electronic annotation. Source: EC thiamine pyrophosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	I5AMT5 [UniParc]. Last modified September 5, 2012. Version 1. Checksum: FF04F9E1DAF66EA0	FASTA	738	82,728
	10 20 30 40 50 60 MALKFPTIKR YGGEGAESML AFFWQLLRDS VQANIEHVVL AMPHRGRTPL QAALLNMRPA 70 80 90 100 110 120 KVFRKLSGAS EFGEDIEAMS DVISHFHVSE QLEVLGRPLN FSMVRNPSHL EAANPVAMGK 130 140 150 160 170 180 ARSKQQTRGD GAFGPDSQPF GQHVLNVILH GDAAFAGQGI NQECLNMAYV PHFEVGGSLH 190 200 210 220 230 240 LIVNNQVGFT TPGDRGRSTA YTSDLAKSIQ APVFHVNGDD PEALARISKL AFRYQREFRK 250 260 270 280 290 300 DIFIDLNCFR RWGHNELDDP TFTNPLVYQI VHQRQSVPDL YVQRLAKEEV LSESQAKEMR 310 320 330 340 350 360 DNYMKYLGEE LALAPSYQPP PTYFEKQWAG LQLAPSKELT YWDTGVDYGL LHFIGQQSVS 370 380 390 400 410 420 YPADFNIHPH LQKTFVNARL KKLEAGSKID WATAEALALG SLMYQGHNIR ISGEDVGRGT 430 440 450 460 470 480 FSHRHAMLVD QNTNEMFIPL NSMEGGNGGK LELAHSILSE EAVLGFEYGM AIDNPQNLII 490 500 510 520 530 540 WEAQFGDFAN GAQIIIDAFI VSGETKWMES NALVMLLPHG YDGAASEHSS CRIERFLQLC 550 560 570 580 590 600 DSKETSADGD SVNVHIVSPT TPAQYYHVLR RQLARNFRKP LVVVGPKTLL RLPAATSTHE 610 620 630 640 650 660 DFQPGTLFHN VLGDTKVQAD QVRKVVLCSG KHYYALAEER EKRQAYDTAI LRLESLCPFP 670 680 690 700 710 720 LQELQAQLAQ YGHVQSFVWS QEEHRNMGAW TFVRPRFENL IGQQLHYCGR YEAPTPATGI 730 GKVHKREVDE IVAAPFEL

References

[1]

"Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution." Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S., Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P., Couronne O., Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J., van Batenburg M.F., Howells S.L. , Scherer S.E., Sodergren E., Matthews B.B., Crosby M.A., Schroeder A.J., Ortiz-Barrientos D., Rives C.M., Metzker M.L., Muzny D.M., Scott G., Steffen D., Wheeler D.A., Worley K.C., Havlak P., Durbin K.J., Egan A., Gill R., Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y., Waldron L., Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.F., Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.M., Weinstock G.M., Gibbs R.A. Genome Res. 15:1-18(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MV2-25 / Tucson 14011-0121.94.

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Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CM000070 Genomic DNA. Translation: EIM52270.1.
RefSeq	XP_003736197.1. XM_003736149.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0304082; FBpp0293043; FBgn0073766.
GeneID	4800345.
KEGG	dpo:Dpse_GA13730.
Organism-specific databases
FlyBase	FBgn0073766. Dpse\GA13730.
Phylogenomic databases
KO	K15791.
Family and domain databases
InterPro	IPR011603. 2oxoglutarate_DH_E1. IPR001017. DH_E1. IPR005475. Transketolase-like_Pyr-bd. [Graphical view]
PANTHER	PTHR23152. PTHR23152. 1 hit.
Pfam	PF00676. E1_dh. 1 hit. PF02779. Transket_pyr. 1 hit. [Graphical view]
PIRSF	PIRSF000157. Oxoglu_dh_E1. 1 hit.
SMART	SM00861. Transket_pyr. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

I5AMT5_DROPS

Accession

Primary (citable) accession number: I5AMT5

Entry history

Integrated into UniProtKB/TrEMBL:	September 5, 2012
Last sequence update:	September 5, 2012
Last modified:	May 29, 2013
This is version 7 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)