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I5AMT5

- I5AMT5_DROPS

UniProt

I5AMT5 - I5AMT5_DROPS

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Protein
Submitted name:

GA13730, isoform B

Gene

Dpse\GA13730

Organism
Drosophila pseudoobscura pseudoobscura (Fruit fly)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. oxoglutarate dehydrogenase (succinyl-transferring) activity Source: UniProtKB-EC
  2. thiamine pyrophosphate binding Source: InterPro

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
GA13730, isoform BImported (EC:1.2.4.2Imported)
Gene namesi
Name:Dpse\GA13730Imported
ORF Names:Dpse_GA13730Imported, GA13730Imported
OrganismiDrosophila pseudoobscura pseudoobscura (Fruit fly)Imported
Taxonomic identifieri46245 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000001819: Chromosome 2

Organism-specific databases

FlyBaseiFBgn0073766. Dpse\GA13730.

Family & Domainsi

Phylogenomic databases

KOiK15791.
OrthoDBiEOG7CZK4Z.

Family and domain databases

Gene3Di3.40.50.970. 2 hits.
InterProiIPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.

Sequencei

Sequence statusi: Complete.

I5AMT5-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MALKFPTIKR YGGEGAESML AFFWQLLRDS VQANIEHVVL AMPHRGRTPL
60 70 80 90 100
QAALLNMRPA KVFRKLSGAS EFGEDIEAMS DVISHFHVSE QLEVLGRPLN
110 120 130 140 150
FSMVRNPSHL EAANPVAMGK ARSKQQTRGD GAFGPDSQPF GQHVLNVILH
160 170 180 190 200
GDAAFAGQGI NQECLNMAYV PHFEVGGSLH LIVNNQVGFT TPGDRGRSTA
210 220 230 240 250
YTSDLAKSIQ APVFHVNGDD PEALARISKL AFRYQREFRK DIFIDLNCFR
260 270 280 290 300
RWGHNELDDP TFTNPLVYQI VHQRQSVPDL YVQRLAKEEV LSESQAKEMR
310 320 330 340 350
DNYMKYLGEE LALAPSYQPP PTYFEKQWAG LQLAPSKELT YWDTGVDYGL
360 370 380 390 400
LHFIGQQSVS YPADFNIHPH LQKTFVNARL KKLEAGSKID WATAEALALG
410 420 430 440 450
SLMYQGHNIR ISGEDVGRGT FSHRHAMLVD QNTNEMFIPL NSMEGGNGGK
460 470 480 490 500
LELAHSILSE EAVLGFEYGM AIDNPQNLII WEAQFGDFAN GAQIIIDAFI
510 520 530 540 550
VSGETKWMES NALVMLLPHG YDGAASEHSS CRIERFLQLC DSKETSADGD
560 570 580 590 600
SVNVHIVSPT TPAQYYHVLR RQLARNFRKP LVVVGPKTLL RLPAATSTHE
610 620 630 640 650
DFQPGTLFHN VLGDTKVQAD QVRKVVLCSG KHYYALAEER EKRQAYDTAI
660 670 680 690 700
LRLESLCPFP LQELQAQLAQ YGHVQSFVWS QEEHRNMGAW TFVRPRFENL
710 720 730
IGQQLHYCGR YEAPTPATGI GKVHKREVDE IVAAPFEL
Length:738
Mass (Da):82,728
Last modified:September 5, 2012 - v1
Checksum:iFF04F9E1DAF66EA0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000070 Genomic DNA. Translation: EIM52270.1.
RefSeqiXP_003736197.1. XM_003736149.1.

Genome annotation databases

EnsemblMetazoaiFBtr0304082; FBpp0293043; FBgn0073766.
GeneIDi4800345.
KEGGidpo:Dpse_GA13730.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000070 Genomic DNA. Translation: EIM52270.1 .
RefSeqi XP_003736197.1. XM_003736149.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai FBtr0304082 ; FBpp0293043 ; FBgn0073766 .
GeneIDi 4800345.
KEGGi dpo:Dpse_GA13730.

Organism-specific databases

FlyBasei FBgn0073766. Dpse\GA13730.

Phylogenomic databases

KOi K15791.
OrthoDBi EOG7CZK4Z.

Family and domain databases

Gene3Di 3.40.50.970. 2 hits.
InterProi IPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view ]
PANTHERi PTHR23152. PTHR23152. 1 hit.
Pfami PF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view ]
PIRSFi PIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTi SM00861. Transket_pyr. 1 hit.
[Graphical view ]
SUPFAMi SSF52518. SSF52518. 2 hits.
ProtoNeti Search...

Publicationsi

  1. "Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution."
    Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S., Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P., Couronne O., Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J., van Batenburg M.F., Howells S.L.
    , Scherer S.E., Sodergren E., Matthews B.B., Crosby M.A., Schroeder A.J., Ortiz-Barrientos D., Rives C.M., Metzker M.L., Muzny D.M., Scott G., Steffen D., Wheeler D.A., Worley K.C., Havlak P., Durbin K.J., Egan A., Gill R., Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y., Waldron L., Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.F., Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.M., Weinstock G.M., Gibbs R.A.
    Genome Res. 15:1-18(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MV2-25 / Tucson 14011-0121.94Imported.
  2. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MV2-25Imported.

Entry informationi

Entry nameiI5AMT5_DROPS
AccessioniPrimary (citable) accession number: I5AMT5
Entry historyi
Integrated into UniProtKB/TrEMBL: September 5, 2012
Last sequence update: September 5, 2012
Last modified: October 1, 2014
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3