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I4IY78

- I4IY78_HUMAN

UniProt

I4IY78 - I4IY78_HUMAN

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Protein
Submitted name:

MHC class I antigen

Gene

HLA-B

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. peptide antigen binding Source: InterPro

GO - Biological processi

  1. antigen processing and presentation of peptide antigen via MHC class I Source: InterPro
  2. immune response Source: InterPro
  3. positive regulation of T cell mediated cytotoxicity Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
MHC class I antigenImported
Gene namesi
Name:HLA-BImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. MHC class I protein complex Source: InterPro
Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliI4IY78.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MHC class I family.UniRule annotation

Family and domain databases

Gene3Di3.30.500.10. 1 hit.
InterProiIPR011161. MHC_I-like_Ag-recog.
IPR011162. MHC_I/II-like_Ag-recog.
IPR027648. MHC_I_a.
IPR001039. MHC_I_a_a1/a2.
[Graphical view]
PfamiPF00129. MHC_I. 1 hit.
[Graphical view]
PRINTSiPR01638. MHCCLASSI.
SUPFAMiSSF54452. SSF54452. 1 hit.

Sequencei

Sequence statusi: Fragment.

I4IY78-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
LPLHEVFPHL RVPARPRGAP LHHRGLRGRH PVREVRQRRR ESEDGAPGAV
60 70 80 90 100
DRARGAGVLG PEHTDLQDQH TDLPREPAEP ARLLQPERGR SHTLQRMYGC
110 120 130 140 150
DVGPDGRLLR GHDQSAYDGK DYIALNEDLS SWTAADTAAQ ITQRKWEAAR
160
VAEQLRAYLE GTCV
Length:164
Mass (Da):18,392
Last modified:October 3, 2012 - v2
Checksum:iC751A69BC62D0945
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei164 – 1641Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE860493 Genomic DNA. Translation: CCI69287.2.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE860493 Genomic DNA. Translation: CCI69287.2 .

3D structure databases

ProteinModelPortali I4IY78.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

ChiTaRSi HLA-B. human.
NextBioi 35533846.

Family and domain databases

Gene3Di 3.30.500.10. 1 hit.
InterProi IPR011161. MHC_I-like_Ag-recog.
IPR011162. MHC_I/II-like_Ag-recog.
IPR027648. MHC_I_a.
IPR001039. MHC_I_a_a1/a2.
[Graphical view ]
Pfami PF00129. MHC_I. 1 hit.
[Graphical view ]
PRINTSi PR01638. MHCCLASSI.
SUPFAMi SSF54452. SSF54452. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "A novel HLA-B*18 allele identified by SBT typing in an Italian bone marrow volunteer donor."
    Vecchiato C., Lochmann E., Frison S., Poli F., Moscetti A.
    Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Peripheral bloodImported.

Entry informationi

Entry nameiI4IY78_HUMAN
AccessioniPrimary (citable) accession number: I4IY78
Entry historyi
Integrated into UniProtKB/TrEMBL: September 5, 2012
Last sequence update: October 3, 2012
Last modified: October 29, 2014
This is version 10 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.