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I4IY78

- I4IY78_HUMAN

UniProt

I4IY78 - I4IY78_HUMAN

Protein
Submitted name:

MHC class I antigen

Gene

HLA-B

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein inferred from homologyi
  1. Functioni

    GO - Molecular functioni

    1. peptide antigen binding Source: InterPro

    GO - Biological processi

    1. antigen processing and presentation of peptide antigen via MHC class I Source: InterPro
    2. immune response Source: InterPro
    3. positive regulation of T cell mediated cytotoxicity Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    MHC class I antigenImported
    Gene namesi
    Name:HLA-BImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. MHC class I protein complex Source: InterPro

    Structurei

    3D structure databases

    ProteinModelPortaliI4IY78.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the MHC class I family.UniRule annotation

    Family and domain databases

    Gene3Di3.30.500.10. 1 hit.
    InterProiIPR011161. MHC_I-like_Ag-recog.
    IPR011162. MHC_I/II-like_Ag-recog.
    IPR027648. MHC_I_a.
    IPR001039. MHC_I_a_a1/a2.
    [Graphical view]
    PfamiPF00129. MHC_I. 1 hit.
    [Graphical view]
    PRINTSiPR01638. MHCCLASSI.
    SUPFAMiSSF54452. SSF54452. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    I4IY78-1 [UniParc]FASTAAdd to Basket

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    LPLHEVFPHL RVPARPRGAP LHHRGLRGRH PVREVRQRRR ESEDGAPGAV    50
    DRARGAGVLG PEHTDLQDQH TDLPREPAEP ARLLQPERGR SHTLQRMYGC 100
    DVGPDGRLLR GHDQSAYDGK DYIALNEDLS SWTAADTAAQ ITQRKWEAAR 150
    VAEQLRAYLE GTCV 164
    Length:164
    Mass (Da):18,392
    Last modified:October 3, 2012 - v2
    Checksum:iC751A69BC62D0945
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported
    Non-terminal residuei164 – 1641Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    HE860493 Genomic DNA. Translation: CCI69287.2.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    HE860493 Genomic DNA. Translation: CCI69287.2 .

    3D structure databases

    ProteinModelPortali I4IY78.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Miscellaneous databases

    ChiTaRSi HLA-B. human.
    NextBioi 35533846.

    Family and domain databases

    Gene3Di 3.30.500.10. 1 hit.
    InterProi IPR011161. MHC_I-like_Ag-recog.
    IPR011162. MHC_I/II-like_Ag-recog.
    IPR027648. MHC_I_a.
    IPR001039. MHC_I_a_a1/a2.
    [Graphical view ]
    Pfami PF00129. MHC_I. 1 hit.
    [Graphical view ]
    PRINTSi PR01638. MHCCLASSI.
    SUPFAMi SSF54452. SSF54452. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "A novel HLA-B*18 allele identified by SBT typing in an Italian bone marrow volunteer donor."
      Vecchiato C., Lochmann E., Frison S., Poli F., Moscetti A.
      Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: Peripheral bloodImported.

    Entry informationi

    Entry nameiI4IY78_HUMAN
    AccessioniPrimary (citable) accession number: I4IY78
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 5, 2012
    Last sequence update: October 3, 2012
    Last modified: October 1, 2014
    This is version 9 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.