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I4E1A6 (I4E1A6_STRIJ) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 12. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length368 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 RuleBase RU004247 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201 RuleBase RU004247

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site401Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2631Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1361Substrate By similarity HAMAP-Rule MF_01201
Binding site3101Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue401N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
I4E1A6 [UniParc].

Last modified September 5, 2012. Version 1.
Checksum: EE810F97C47D724B

FASTA36840,166
        10         20         30         40         50         60 
MKTSNHRPTK AIVDLAAIHF NIKQIAAHIP GDVEKWAVVK ADAYGHGAVA VTQSIEPIVD 

        70         80         90        100        110        120 
GFCVSNIDEA LELREAGISK KILVLGVSTI QSVPLAMKYK ITYTVASLEW IDLLLQSNID 

       130        140        150        160        170        180 
VTGLVVHIKI DSGMGRIGFR NSQDAQEAIH RLKKVGAQVE GIFTHFATAD EADTQKFAAQ 

       190        200        210        220        230        240 
LARFKEILER LDIVPPIVHA SNSATTLWHA DTVMKAVRLG DIIYGLNPSG RTLELPYEMK 

       250        260        270        280        290        300 
PALSLISELV HVKQLEAGAD IGYGATYTSD SPQFIGTIPL GYADGWTRDM QGFNVLIDGK 

       310        320        330        340        350        360 
ACPVVGRVSM DQITVRLPRF YPIGTSVVFI GKSGEEVISA TDVAEKRGTI NYEVVCLLSD 


RVPRIYKK 

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References

[1]"Complete genome sequencing of Streptococcus intermedius, a pathogen of human purulent infections."
Kikuchi K., Baba T., Sasaki T., Kishii K., Takeuchi F., Watanabe S., Sekine M., Matsuo M., Cui L., Ito T., Hiramatsu K.
Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JTH08 EMBL BAM23946.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP010969 Genomic DNA. Translation: BAM23946.1.
RefSeqYP_006470194.1. NC_018073.1.

3D structure databases

ProteinModelPortalI4E1A6.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAM23946; BAM23946; SCIM_1292.
GeneID13155743.
KEGGsie:SCIM_1292.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01775.

Enzyme and pathway databases

BioCycSINT591365:GLL4-1344-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameI4E1A6_STRIJ
AccessionPrimary (citable) accession number: I4E1A6
Entry history
Integrated into UniProtKB/TrEMBL: September 5, 2012
Last sequence update: September 5, 2012
Last modified: February 19, 2014
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)