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I4DZB8

- I4DZB8_STRIJ

UniProt

I4DZB8 - I4DZB8_STRIJ

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Protein
Elongation factor Tu
Gene
tuf, SCIM_0604
Organism
Streptococcus intermedius (strain JTH08)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 268GTP By similarityUniRule annotation
Nucleotide bindingi84 – 885GTP By similarityUniRule annotation
Nucleotide bindingi139 – 1424GTP By similarityUniRule annotation

GO - Molecular functioni

  1. GTP binding Source: UniProtKB-HAMAP
  2. GTPase activity Source: InterPro
  3. translation elongation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    Elongation factorUniRule annotationImported

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciSINT591365:GLL4-636-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor TuUniRule annotation
    Short name:
    EF-TuUniRule annotation
    Gene namesi
    Name:tufUniRule annotationImported
    Ordered Locus Names:SCIM_0604Imported
    OrganismiStreptococcus intermedius (strain JTH08)Imported
    Taxonomic identifieri591365 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcusStreptococcus anginosus group
    ProteomesiUP000002897: Chromosome

    Subcellular locationi

    Cytoplasm By similarity UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    Complete GO annotation...

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    Interactioni

    Subunit structurei

    Monomer By similarity.UniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    KOiK02358.
    OMAiGTEMCMP.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00118_B. EF_Tu_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS00301. EFACTOR_GTP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    I4DZB8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAKEKYDRSK PHVNIGTIGH VDHGKTTLTA AITTVLARRL PSSVNQPKDY    50
    SSIDAAPEER ERGITINTAH VEYETAKRHY AHIDAPGHAD YVKNMITGAA 100
    QMDGAILVVA STDGPMPQTR EHILLSRQVG VKYLIVFMNK VDLVDDEELL 150
    ELVEMEIRDL LSEYDFPGDD IPVIQGSALK ALEGDEKYED IIMELMNTVD 200
    EYIPEPERDT DKPLLLPVED VFSITGRGTV ASGRIDRGTV KVNDEVEIVG 250
    IREEIQKAVV TGVEMFRKQL DEGLAGDNVG VLLRGIQRDE IERGQVLAKP 300
    GSIHPHTKFK GEVYILTKEE GGRHTPFFNN YRPQFYFRTT DVTGSIELPA 350
    GTEMVMPGDN VTIDVELIHP IAVEQGTTFS IREGGRTVGS GMVTEIEA 398
    Length:398
    Mass (Da):44,062
    Last modified:September 5, 2012 - v1
    Checksum:i9B05FC140EDB4A5E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP010969 Genomic DNA. Translation: BAM23258.1.
    RefSeqiYP_006469506.1. NC_018073.1.

    Genome annotation databases

    EnsemblBacteriaiBAM23258; BAM23258; SCIM_0604.
    GeneIDi13154357.
    KEGGisie:SCIM_0604.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP010969 Genomic DNA. Translation: BAM23258.1 .
    RefSeqi YP_006469506.1. NC_018073.1.

    3D structure databases

    ModBasei Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAM23258 ; BAM23258 ; SCIM_0604 .
    GeneIDi 13154357.
    KEGGi sie:SCIM_0604.

    Phylogenomic databases

    KOi K02358.
    OMAi GTEMCMP.

    Enzyme and pathway databases

    BioCyci SINT591365:GLL4-636-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00118_B. EF_Tu_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS00301. EFACTOR_GTP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequencing of Streptococcus intermedius, a pathogen of human purulent infections."
      Kikuchi K., Baba T., Sasaki T., Kishii K., Takeuchi F., Watanabe S., Sekine M., Matsuo M., Cui L., Ito T., Hiramatsu K.
      Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: JTH08Imported.

    Entry informationi

    Entry nameiI4DZB8_STRIJ
    AccessioniPrimary (citable) accession number: I4DZB8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 5, 2012
    Last sequence update: September 5, 2012
    Last modified: June 11, 2014
    This is version 11 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    External Data

    Dasty 3

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