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I4DZB5

- I4DZB5_STRIJ

UniProt

I4DZB5 - I4DZB5_STRIJ

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Protein

Phosphoenolpyruvate carboxylase

Gene
ppc, SCIM_0601
Organism
Streptococcus intermedius (strain JTH08)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity.UniRule annotationSAAS annotations

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotations

Cofactori

Magnesium By similarity.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381 By similarityUniRule annotation
Active sitei561 – 5611 By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotations

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotations, PyruvateImported

Enzyme and pathway databases

BioCyciSINT591365:GLL4-633-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:SCIM_0601Imported
OrganismiStreptococcus intermedius (strain JTH08)Imported
Taxonomic identifieri591365 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcusStreptococcus anginosus group
ProteomesiUP000002897: Chromosome

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.
OMAiELSTISC.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

I4DZB5-1 [UniParc]FASTAAdd to Basket

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MSLQKLENYN NKEVIQEEVT ILTDLLEEVT QNMLSPETFE KIIALKELAA    50
VGNYEGLNEI VQNLSNKEMF YISRYFSILP LLINISEDVD LAFEINYQNN 100
VGQDYLGKLS TTIDLVAEKE NAAEILEHLN VVPVLTAHPT QVQRTTMLDL 150
TNHIHVLLRK YRDVRMGLLN EEKWHNDLRR YIEIIMRTDM IREKKLKVTN 200
EITNVMEYYN SSLLQAVTNL AEEYKRLAKK HGISLKNPTP ITMGMWIGGD 250
RDGNPYVTSE TLKKSALTQC EVIMNYYDAK IANLYREFSL STGIVKVSEA 300
VQEMAYLSED NSIYREKELY RRAFYYIQTK LKNTKTYFID QAEVEPHYHN 350
IEEFKHDLLA IKQSLLENKG EAMISGEFTE LLQAVEVFGF YLASIDMRQD 400
SSVHEACVAE LLASAGIVEH YSELSEGEKC HVLLNELLYD PRILSATHAE 450
KSDLLQKELQ IFQTARELKD MLGDAVIKQT IISHATSVSD LLELAVMHKE 500
VGLIDKESAR VQIVPLFETI EDLDNSYDTM KKYLSLPIAQ KWIASNNNYQ 550
EIMLGYSDSN KDGGYLSSCW TLYKAQQQLT AIGDEFGVKI TFFHGRGGTV 600
GRGGGPTYEA ITSQPLRSIN DRIRLTEQGE VIGNKYGNKD AAYYNLEMLV 650
SATINRMITK KKSDTNTSNH YESIMDQVVD RSYQIYRDLV FGNEHFYDYF 700
FESSPIKAIS SFNIGSRPAA RKTITEIGGL RAIPWVFSWS QSRVMFPGWY 750
GVGSSFKEFI DENPKENLAF LRKMYKNWPF FRSLLSNVDM VLSKSNMNIA 800
FEYAKLCEDE KVQEIYYTIL DEWQLTKNVI LAIEDYDELL QENPYLRDSL 850
DYRMRYFNIL NYIQLELIKR QRRGELSPDE ERLIHVTING IATGLRNSG 899
Length:899
Mass (Da):103,603
Last modified:September 5, 2012 - v1
Checksum:i5A41981388FC42E9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP010969 Genomic DNA. Translation: BAM23255.1.
RefSeqiYP_006469503.1. NC_018073.1.

Genome annotation databases

EnsemblBacteriaiBAM23255; BAM23255; SCIM_0601.
GeneIDi13155562.
KEGGisie:SCIM_0601.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP010969 Genomic DNA. Translation: BAM23255.1 .
RefSeqi YP_006469503.1. NC_018073.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAM23255 ; BAM23255 ; SCIM_0601 .
GeneIDi 13155562.
KEGGi sie:SCIM_0601.

Phylogenomic databases

KOi K01595.
OMAi ELSTISC.

Enzyme and pathway databases

BioCyci SINT591365:GLL4-633-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequencing of Streptococcus intermedius, a pathogen of human purulent infections."
    Kikuchi K., Baba T., Sasaki T., Kishii K., Takeuchi F., Watanabe S., Sekine M., Matsuo M., Cui L., Ito T., Hiramatsu K.
    Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JTH08Imported.

Entry informationi

Entry nameiI4DZB5_STRIJ
AccessioniPrimary (citable) accession number: I4DZB5
Entry historyi
Integrated into UniProtKB/TrEMBL: September 5, 2012
Last sequence update: September 5, 2012
Last modified: June 11, 2014
This is version 11 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi