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Protein
Submitted name:

Sialidase A

Gene

nanA

Organism
Streptococcus intermedius (strain JTH08)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. exo-alpha-sialidase activity Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

BioCyciSINT591365:GLL4-12-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Sialidase AImported
Gene namesi
Name:nanAImported
Ordered Locus Names:SCIM_0012Imported
OrganismiStreptococcus intermedius (strain JTH08)Imported
Taxonomic identifieri591365 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcusStreptococcus anginosus group
ProteomesiUP000002897 Componenti: Chromosome

Structurei

3D structure databases

ProteinModelPortaliI4DXM6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

KOiK01186.
OMAiGGPKREN.

Family and domain databases

Gene3Di2.120.10.10. 2 hits.
2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR004124. Glyco_hydro_33_N.
IPR001791. Laminin_G.
IPR019931. LPXTG_anchor.
IPR026856. Sialidase_fam.
IPR011040. Sialidases.
[Graphical view]
PANTHERiPTHR10628. PTHR10628. 1 hit.
PfamiPF02973. Sialidase. 1 hit.
[Graphical view]
SMARTiSM00282. LamG. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF50939. SSF50939. 2 hits.
TIGRFAMsiTIGR01167. LPXTG_anchor. 1 hit.
PROSITEiPS50847. GRAM_POS_ANCHORING. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

I4DXM6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNWSFFDWKK QDKIRKLVVG ATFIVIGIAI FLALSGLKQV NTVLANTKKV
60 70 80 90 100
ESGINNSIAD LLKETNVIPR DYYARQLENV QTIFEKENVV TNDSNNQRID
110 120 130 140 150
LSGELDKLKQ LQTATIHIEF KADANAPRFY NLFSVSSDKV KNEYFTMAVY
160 170 180 190 200
NNTAIVEGRD KDGKQFYNSY NDAPLKIKSG QWNSVTFTVD GPNSDHPNGQ
210 220 230 240 250
VRLYVNGVLS RTSKLSGRFI KDMPDVNHVQ IGKTNRAGSM MWGSNLHVRN
260 270 280 290 300
LTVYNRALTS EEVQKRSQLF KRSDLEKRLP EGALLTEKTD VFKSGYNNQP
310 320 330 340 350
NSEGINSYRI PALLRTDKGT LIAGADQRRL HHADYGDIGM VVRRSEDNGK
360 370 380 390 400
TWGDKKVLSN LRDNPDAKDP VAPSPLNIDM TLVQDPTTKR IFAIYDMFPE
410 420 430 440 450
GKGIFGMPKI NEKAYEQVGD KTYQILYKQG EFGHYTIREN GEVYDANNQK
460 470 480 490 500
TDYRVVVNPT KADYRDKGDI YKGQELVGNI YFAQSKKNPF RIAYTSYLWM
510 520 530 540 550
SYSDDDGKTW SAPRDITSGV RKDWMKFLGT GPGTGIVLRT GKHKGRILIP
560 570 580 590 600
VYTTNNVSHL NGSQSSRLIY SDDHGETWHA GEAINDNRQV GGQKIHSSTM
610 620 630 640 650
NNRNAQNTES TVVQLNNGDI KLFMRGLMGD LQVATSKDGG ATWEKEIKRY
660 670 680 690 700
PQVKDVYVQM SAIHTMHDGI EYVVLSNAGG PERTNGLVHL ARVEKNGELT
710 720 730 740 750
WLKHNLIQKG EFAYNSLQDL GNGEYGLFYE HRENGQNPYT LSYKKFNWDF
760 770 780 790 800
LSKDLISPKE VKVKKAVDRG KGVVGLEFDS EVLVNQAPTL KLTNGKIATF
810 820 830 840 850
ITQYDSKTLL FKVDKGAIGQ KITGLASGSI ESIHNLPVNL TGASIPGGVN
860 870 880 890 900
GGKGTVNEVP EYKEKKSTKK PATEKKQANK VLTNHHNLPS TGSTTNVSIL
910 920
FLGIATIILG LLTMINKRKQ
Length:920
Mass (Da):103,023
Last modified:September 5, 2012 - v1
Checksum:iD0D1827F7C1D13C6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP010969 Genomic DNA. Translation: BAM22666.1.
RefSeqiYP_006468914.1. NC_018073.1.

Genome annotation databases

EnsemblBacteriaiBAM22666; BAM22666; SCIM_0012.
KEGGisie:SCIM_0012.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP010969 Genomic DNA. Translation: BAM22666.1.
RefSeqiYP_006468914.1. NC_018073.1.

3D structure databases

ProteinModelPortaliI4DXM6.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAM22666; BAM22666; SCIM_0012.
KEGGisie:SCIM_0012.

Phylogenomic databases

KOiK01186.
OMAiGGPKREN.

Enzyme and pathway databases

BioCyciSINT591365:GLL4-12-MONOMER.

Family and domain databases

Gene3Di2.120.10.10. 2 hits.
2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR004124. Glyco_hydro_33_N.
IPR001791. Laminin_G.
IPR019931. LPXTG_anchor.
IPR026856. Sialidase_fam.
IPR011040. Sialidases.
[Graphical view]
PANTHERiPTHR10628. PTHR10628. 1 hit.
PfamiPF02973. Sialidase. 1 hit.
[Graphical view]
SMARTiSM00282. LamG. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF50939. SSF50939. 2 hits.
TIGRFAMsiTIGR01167. LPXTG_anchor. 1 hit.
PROSITEiPS50847. GRAM_POS_ANCHORING. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequencing of Streptococcus intermedius, a pathogen of human purulent infections."
    Kikuchi K., Baba T., Sasaki T., Kishii K., Takeuchi F., Watanabe S., Sekine M., Matsuo M., Cui L., Ito T., Hiramatsu K.
    Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JTH08Imported.

Entry informationi

Entry nameiI4DXM6_STRIJ
AccessioniPrimary (citable) accession number: I4DXM6
Entry historyi
Integrated into UniProtKB/TrEMBL: September 5, 2012
Last sequence update: September 5, 2012
Last modified: April 1, 2015
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.