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I4C4C0

- I4C4C0_DESTA

UniProt

I4C4C0 - I4C4C0_DESTA

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Protein
Submitted name: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
Gene
Desti_1700
Organism
Desulfomonile tiedjei (strain ATCC 49306 / DSM 6799 / DCB-1)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Cofactori

Pyridoxal phosphate By similarity.SAAS annotations

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity Source: UniProtKB-EC
  3. UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity Source: InterPro
  4. alanine racemase activity Source: InterPro

GO - Biological processi

  1. alanine metabolic process Source: InterPro
  2. biosynthetic process Source: InterPro
  3. cell division Source: InterPro
  4. regulation of cell shape Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseSAAS annotations, LigaseImported

Keywords - Ligandi

Pyridoxal phosphateSAAS annotations

Enzyme and pathway databases

BioCyciDTIE706587:GLCI-1698-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligaseImported (EC:6.3.2.10Imported)
Gene namesi
Ordered Locus Names:Desti_1700Imported
OrganismiDesulfomonile tiedjei (strain ATCC 49306 / DSM 6799 / DCB-1)Imported
Taxonomic identifieri706587 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaSyntrophobacteralesSyntrophaceaeDesulfomonile
ProteomesiUP000006055: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: InterPro
Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliI4C4C0.

Family & Domainsi

Phylogenomic databases

KOiK01775.
OMAiMHENASI.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
3.40.1190.10. 1 hit.
3.40.1390.10. 1 hit.
3.90.190.20. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR004101. Mur_ligase_C.
IPR013221. Mur_ligase_cen.
IPR000713. Mur_ligase_N.
IPR029066. PLP-binding_barrel.
IPR005863. UDP-N-AcMur-pentapeptide_synth.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
PF01225. Mur_ligase. 1 hit.
PF02875. Mur_ligase_C. 1 hit.
PF08245. Mur_ligase_M. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
SSF53244. SSF53244. 1 hit.
SSF53623. SSF53623. 1 hit.
SSF63418. SSF63418. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
TIGR01143. murF. 1 hit.

Sequencei

Sequence statusi: Complete.

I4C4C0-1 [UniParc]FASTAAdd to Basket

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MISETTKNST PIADAECVDP VSACARSNSV EKQGIANTGF LDLSELIGIL    50
KPIRVQGPLA GPISGISIDT RKPMSEDFIF WAIRGEHFNG NDFVEDALSA 100
GARAVVASRD DCFQNGSWPD ATLIQVQDTL QALQDLAATY RNRFRYPVIG 150
ITGSNGKTLV KEMLASILCL ERKTYRSPLS YNTQIGAALG LLGMRPEHQV 200
AIIEAGISLP GEMDRLERMI RPDHGILTII SKAHIGGLGT LENTIAEKRR 250
LFKNLKEDSF LVLNADDPLS MELAQDSKAR VVTFGMSPQA DVRAENITSI 300
PDRGHQFIMQ IFGNAQQIML PVAGRFNVLN ALAASAAATL LGASPEAIAE 350
GLKDFRPSPM RLEMHTTVTG VTLINDTYNS DPVSVKGALD VLAKVGKGRR 400
KIAILSEMLD LGLHSREEHL AVGKEVVRSQ VDQLITVGEN AAIIGHAAAT 450
EGMNPKRITH TRSHKEAALE LEKIMNRGDV VLFKGSRWFR LERIAKELVG 500
SIGATRLLVN LDAIAANVKK IRGIVGEDVA IMSVVKSFGY GNDSIRTSRV 550
ALENGANYLA VAFPDEGTTL RENRIDAPIL VFNVLPEEVD KIIKHDLSCV 600
VASLETAAAL DRAATGRRKI PVHVKIDTGM GRSGIWVEDA VPFIEQVLCF 650
RNLAVEGIMT HFSSADDPAS DDYTLQQITA FEALLSELKQ RGHSFRYIHA 700
ANTSALVRFP QTHYTMVRPG LAIYGMYPSE AVKSYIQLEQ VIAFTTKIAQ 750
LKEHPPGRCI SYNRRYVTSR NCRIATLHVG YNDGYPRFQS NVGEVLVHGK 800
RAPVVGTVCM DTIMIDVTEI PEARVGDEVV LIGKQGDEEI LPDDIAANGN 850
TINYEIACKI SPRVTRIFVQ S 871
Length:871
Mass (Da):95,148
Last modified:September 5, 2012 - v1
Checksum:iF513B2A430A6A3A4
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003360 Genomic DNA. Translation: AFM24411.1.
RefSeqiYP_006446675.1. NC_018025.1.

Genome annotation databases

EnsemblBacteriaiAFM24411; AFM24411; Desti_1700.
GeneIDi13138745.
KEGGidti:Desti_1700.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003360 Genomic DNA. Translation: AFM24411.1 .
RefSeqi YP_006446675.1. NC_018025.1.

3D structure databases

ProteinModelPortali I4C4C0.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFM24411 ; AFM24411 ; Desti_1700 .
GeneIDi 13138745.
KEGGi dti:Desti_1700.

Phylogenomic databases

KOi K01775.
OMAi MHENASI.

Enzyme and pathway databases

BioCyci DTIE706587:GLCI-1698-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
3.40.1190.10. 1 hit.
3.40.1390.10. 1 hit.
3.90.190.20. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR004101. Mur_ligase_C.
IPR013221. Mur_ligase_cen.
IPR000713. Mur_ligase_N.
IPR029066. PLP-binding_barrel.
IPR005863. UDP-N-AcMur-pentapeptide_synth.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
PF01225. Mur_ligase. 1 hit.
PF02875. Mur_ligase_C. 1 hit.
PF08245. Mur_ligase_M. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
SSF53244. SSF53244. 1 hit.
SSF53623. SSF53623. 1 hit.
SSF63418. SSF63418. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
TIGR01143. murF. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 49306 / DSM 6799 / DCB-1.

Entry informationi

Entry nameiI4C4C0_DESTA
AccessioniPrimary (citable) accession number: I4C4C0
Entry historyi
Integrated into UniProtKB/TrEMBL: September 5, 2012
Last sequence update: September 5, 2012
Last modified: June 11, 2014
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3