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I4C4C0

- I4C4C0_DESTA

UniProt

I4C4C0 - I4C4C0_DESTA

Protein
Submitted name:

UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase

Gene

Desti_1700

Organism
Desulfomonile tiedjei (strain ATCC 49306 / DSM 6799 / DCB-1)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 15 (01 Oct 2014)
      Sequence version 1 (05 Sep 2012)
      Previous versions | rss
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    Functioni

    Cofactori

    Pyridoxal phosphate.SAAS annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: InterPro
    2. ATP binding Source: InterPro
    3. UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity Source: InterPro
    4. UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity Source: UniProtKB-EC

    GO - Biological processi

    1. alanine metabolic process Source: InterPro
    2. biosynthetic process Source: InterPro
    3. cell division Source: InterPro
    4. regulation of cell shape Source: InterPro

    Keywords - Molecular functioni

    IsomeraseSAAS annotation, LigaseImported

    Keywords - Ligandi

    Pyridoxal phosphateSAAS annotation

    Enzyme and pathway databases

    BioCyciDTIE706587:GLCI-1698-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligaseImported (EC:6.3.2.10Imported)
    Gene namesi
    Ordered Locus Names:Desti_1700Imported
    OrganismiDesulfomonile tiedjei (strain ATCC 49306 / DSM 6799 / DCB-1)Imported
    Taxonomic identifieri706587 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaSyntrophobacteralesSyntrophaceaeDesulfomonile
    ProteomesiUP000006055: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: InterPro

    Structurei

    3D structure databases

    ProteinModelPortaliI4C4C0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    KOiK01775.
    OMAiMHENASI.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    3.40.1190.10. 1 hit.
    3.40.1390.10. 1 hit.
    3.90.190.20. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR004101. Mur_ligase_C.
    IPR013221. Mur_ligase_cen.
    IPR000713. Mur_ligase_N.
    IPR029066. PLP-binding_barrel.
    IPR005863. UDP-N-AcMur-pentapeptide_synth.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    PF01225. Mur_ligase. 1 hit.
    PF02875. Mur_ligase_C. 1 hit.
    PF08245. Mur_ligase_M. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    SSF53244. SSF53244. 1 hit.
    SSF53623. SSF53623. 1 hit.
    SSF63418. SSF63418. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.
    TIGR01143. murF. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    I4C4C0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MISETTKNST PIADAECVDP VSACARSNSV EKQGIANTGF LDLSELIGIL    50
    KPIRVQGPLA GPISGISIDT RKPMSEDFIF WAIRGEHFNG NDFVEDALSA 100
    GARAVVASRD DCFQNGSWPD ATLIQVQDTL QALQDLAATY RNRFRYPVIG 150
    ITGSNGKTLV KEMLASILCL ERKTYRSPLS YNTQIGAALG LLGMRPEHQV 200
    AIIEAGISLP GEMDRLERMI RPDHGILTII SKAHIGGLGT LENTIAEKRR 250
    LFKNLKEDSF LVLNADDPLS MELAQDSKAR VVTFGMSPQA DVRAENITSI 300
    PDRGHQFIMQ IFGNAQQIML PVAGRFNVLN ALAASAAATL LGASPEAIAE 350
    GLKDFRPSPM RLEMHTTVTG VTLINDTYNS DPVSVKGALD VLAKVGKGRR 400
    KIAILSEMLD LGLHSREEHL AVGKEVVRSQ VDQLITVGEN AAIIGHAAAT 450
    EGMNPKRITH TRSHKEAALE LEKIMNRGDV VLFKGSRWFR LERIAKELVG 500
    SIGATRLLVN LDAIAANVKK IRGIVGEDVA IMSVVKSFGY GNDSIRTSRV 550
    ALENGANYLA VAFPDEGTTL RENRIDAPIL VFNVLPEEVD KIIKHDLSCV 600
    VASLETAAAL DRAATGRRKI PVHVKIDTGM GRSGIWVEDA VPFIEQVLCF 650
    RNLAVEGIMT HFSSADDPAS DDYTLQQITA FEALLSELKQ RGHSFRYIHA 700
    ANTSALVRFP QTHYTMVRPG LAIYGMYPSE AVKSYIQLEQ VIAFTTKIAQ 750
    LKEHPPGRCI SYNRRYVTSR NCRIATLHVG YNDGYPRFQS NVGEVLVHGK 800
    RAPVVGTVCM DTIMIDVTEI PEARVGDEVV LIGKQGDEEI LPDDIAANGN 850
    TINYEIACKI SPRVTRIFVQ S 871
    Length:871
    Mass (Da):95,148
    Last modified:September 5, 2012 - v1
    Checksum:iF513B2A430A6A3A4
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003360 Genomic DNA. Translation: AFM24411.1.
    RefSeqiYP_006446675.1. NC_018025.1.

    Genome annotation databases

    EnsemblBacteriaiAFM24411; AFM24411; Desti_1700.
    GeneIDi13138745.
    KEGGidti:Desti_1700.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003360 Genomic DNA. Translation: AFM24411.1 .
    RefSeqi YP_006446675.1. NC_018025.1.

    3D structure databases

    ProteinModelPortali I4C4C0.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AFM24411 ; AFM24411 ; Desti_1700 .
    GeneIDi 13138745.
    KEGGi dti:Desti_1700.

    Phylogenomic databases

    KOi K01775.
    OMAi MHENASI.

    Enzyme and pathway databases

    BioCyci DTIE706587:GLCI-1698-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    3.40.1190.10. 1 hit.
    3.40.1390.10. 1 hit.
    3.90.190.20. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR004101. Mur_ligase_C.
    IPR013221. Mur_ligase_cen.
    IPR000713. Mur_ligase_N.
    IPR029066. PLP-binding_barrel.
    IPR005863. UDP-N-AcMur-pentapeptide_synth.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    PF01225. Mur_ligase. 1 hit.
    PF02875. Mur_ligase_C. 1 hit.
    PF08245. Mur_ligase_M. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    SSF53244. SSF53244. 1 hit.
    SSF53623. SSF53623. 1 hit.
    SSF63418. SSF63418. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    TIGR01143. murF. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 49306 / DSM 6799 / DCB-1Imported.

    Entry informationi

    Entry nameiI4C4C0_DESTA
    AccessioniPrimary (citable) accession number: I4C4C0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 5, 2012
    Last sequence update: September 5, 2012
    Last modified: October 1, 2014
    This is version 15 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3