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I4BIU9

- I4BIU9_MYCCN

UniProt

I4BIU9 - I4BIU9_MYCCN

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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Mycobacterium chubuense (strain NBB4)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Magnesium.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei159 – 1591UniRule annotation
Active sitei599 – 5991UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciMCHU710421:GLGL-2431-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Mycch_2433Imported
OrganismiMycobacterium chubuense (strain NBB4)Imported
Taxonomic identifieri710421 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
ProteomesiUP000006057: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

I4BIU9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAQTSDLAPI GSVQRTQGGR EATEPMREDI RLLGAILGDT VREQNGEETF
60 70 80 90 100
DLVERARVES FRVRRSEIDR SELATLFDGI DVGEAIPVIR AFTHFALLAN
110 120 130 140 150
VAEDIHRERR RAIHEAAGEP PQNSSLAATY LKLDGADLDA ATVADALTGA
160 170 180 190 200
LVAPVITAHP TETRRRTVFD TQHRITELMR LRLHGHTTTD DGRDLERELR
210 220 230 240 250
RHILTLWQTA LIRLSRLKIS DEIETGLRYY PAAFFDVIPE VNAQVRAALQ
260 270 280 290 300
ARWPDAGLLE EPILRPGSWI GGDRDGNPNV TADVVRLATG SAAYTAFAHY
310 320 330 340 350
LSELTALEQE LSMSVRLVHI TDALAALADA CHEPARADEP YRRALRVVHA
360 370 380 390 400
RLTATARQIL DRRAEHELDL GMEAYEAPAE LLADLDVIDA SLRGHGSAVL
410 420 430 440 450
ADDRLGRLRE AVRVFGFHLS GLDMRQNSDV HEEVVAELLA WAGVHTDYMS
460 470 480 490 500
LSEPERVDLL AAELATRRPL TGPGAVGVPP ACGGLSELAR KELDIVSAAA
510 520 530 540 550
RAVHVFGAQA VPNYIISMCR SVSDMLEAAI LLKEAGLLDA SSETPYAPVG
560 570 580 590 600
IVPLFETIDD LQRGSATLEA ALDLPLYRAV VAARGDSQEV MLGYSDSNKD
610 620 630 640 650
GGYLAANWAL YRAELDLVES ARKTGIRLRL FHGRGGTVGR GGGPSYEAIL
660 670 680 690 700
AQPPGAVRGS LRITEQGEVI AAKYAEPRIA HRNLETLLAA TLEATLLDVE
710 720 730 740 750
GLGDAAGPAY EVLDDLAERA QRAYAELVHE TPGFVDYFKA STPVSEIGAL
760 770 780 790 800
NIGSRPTSRK PTTSISDLRA IPWVLAWSQS RVMLPGWYGT GTAFEHWIDD
810 820 830 840 850
GNDPDARLEV LRDLYRRWPF FATVLSNMAQ VLAKSDLGLA ARYAELVDDE
860 870 880 890 900
ALRRRVFDKI ADEHERTIRM YKMITGQDDL LADNPALARS VFNRFPYLEP
910 920 930 940
LNHLQVELLR RYRSGDEDEL VQRGILLTMS GLATALRNSG
Length:940
Mass (Da):103,189
Last modified:September 5, 2012 - v1
Checksum:i3C901AADC9C3CD36
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003053 Genomic DNA. Translation: AFM17206.1.
RefSeqiWP_014815686.1. NC_018027.1.
YP_006452885.1. NC_018027.1.

Genome annotation databases

EnsemblBacteriaiAFM17206; AFM17206; Mycch_2433.
GeneIDi13142610.
KEGGimcb:Mycch_2433.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003053 Genomic DNA. Translation: AFM17206.1 .
RefSeqi WP_014815686.1. NC_018027.1.
YP_006452885.1. NC_018027.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFM17206 ; AFM17206 ; Mycch_2433 .
GeneIDi 13142610.
KEGGi mcb:Mycch_2433.

Phylogenomic databases

KOi K01595.

Enzyme and pathway databases

BioCyci MCHU710421:GLGL-2431-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome of Mycobacterium chubuense NBB4."
    US DOE Joint Genome Institute
    Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Mikhailova N., Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Mattes T.
    , Holmes A., Rutledge P., Paulsen I., Coleman N., Woyke T.
    Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NBB4Imported.

Entry informationi

Entry nameiI4BIU9_MYCCN
AccessioniPrimary (citable) accession number: I4BIU9
Entry historyi
Integrated into UniProtKB/TrEMBL: September 5, 2012
Last sequence update: September 5, 2012
Last modified: October 29, 2014
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3