Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

UniProtKB - I4BGZ8 (I4BGZ8_MYCCN)

UniProt

I4BGZ8 - I4BGZ8_MYCCN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Probable DNA ligase

Gene

lig

Organism
Mycobacterium chubuense (strain NBB4)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.UniRule annotation

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei213 – 2131ATPUniRule annotation
Active sitei215 – 2151N6-AMP-lysine intermediateUniRule annotation
Binding sitei220 – 2201ATPUniRule annotation
Binding sitei235 – 2351ATPUniRule annotation
Binding sitei264 – 2641ATPUniRule annotation
Binding sitei303 – 3031ATPUniRule annotation
Binding sitei375 – 3751ATPUniRule annotation
Binding sitei381 – 3811ATPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationImported

Keywords - Biological processi

Cell cycle, Cell divisionUniRule annotation, DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, MagnesiumUniRule annotation, Metal-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciMCHU710421:GLGL-1763-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Alternative name(s):
Polydeoxyribonucleotide synthase [ATP]UniRule annotation
Gene namesi
Name:ligUniRule annotation
Ordered Locus Names:Mycch_1764Imported
OrganismiMycobacterium chubuense (strain NBB4)Imported
Taxonomic identifieri710421 [NCBI]
Taxonomic lineageiBacteria › Actinobacteria › Corynebacteriales › Mycobacteriaceae › Mycobacterium ›
Proteomesi
  • UP000006057 Componenti: Chromosome

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini291 – 415125DNA_LIGASE_A3InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

KOiK10747.
OMAiDVETLDC.
OrthoDBiPOG091H0BGA.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 2 hits.
HAMAPiMF_00407. DNA_ligase. 1 hit.
InterProiIPR022865. DNA_ligae_ATP-dep_bac/arc.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

I4BGZ8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLLVEVAQAS ADVAAASARL AKIARIADLL RSAAAAGDPR LVAVVVSWLS 
        60         70         80         90        100
GELTQRQIGV GWASLRALPE PAAEPTLTVL GVDGALGDIG TTSGKGSQAR 
       110        120        130        140        150
RARLVAELFS AATAIEQTFL RRLLTGELRQ GALVGVMADA VSKAAGIDPA 
       160        170        180        190        200
AARRAAMLSG DLPTVAAAAV TGGVAALEAF TLQVGRPVGP MLAQTATSVA 
       210        220        230        240        250
DALERLDGRA VFEAKLDGAR VQIHRRGDSV SVFTRSLDDV TARLPEVVDA 
       260        270        280        290        300
ALALPVTDLI ADAEAIALRP DGRPQRFQVT ASRFGRRGGT AGPDTQKLSV 
       310        320        330        340        350
FFFDLLHVDG VDVLDQPAHE RVARLDAIVP DRQRVDRLLT TDPAEAQTFL 
       360        370        380        390        400
DTTLAAGHEG VMAKSPTAPY EAGRRGAGWL KVKPVHTLDL VVLAVEWGSG 
       410        420        430        440        450
RRTGKLSNIH LGARDPQTGG FVMLGKTFKG MTDEMLAWQT ERFLELADGL 
       460        470        480        490        500
TSGYSVRVRP EQVVEIAFDG LQTSSRYPGG MALRFARVLR YRDDKSAAEA 
       510 
DTIDTVRALY ERSD
Length:514
Mass (Da):54,463
Last modified:September 5, 2012 - v1
Checksum:i593838EFAEA08301
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003053 Genomic DNA. Translation: AFM16555.1.
RefSeqiWP_014815036.1. NC_018027.1.

Genome annotation databases

EnsemblBacteriaiAFM16555; AFM16555; Mycch_1764.
KEGGimcb:Mycch_1764.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003053 Genomic DNA. Translation: AFM16555.1.
RefSeqiWP_014815036.1. NC_018027.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFM16555; AFM16555; Mycch_1764.
KEGGimcb:Mycch_1764.

Phylogenomic databases

KOiK10747.
OMAiDVETLDC.
OrthoDBiPOG091H0BGA.

Enzyme and pathway databases

BioCyciMCHU710421:GLGL-1763-MONOMER.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 2 hits.
HAMAPiMF_00407. DNA_ligase. 1 hit.
InterProiIPR022865. DNA_ligae_ATP-dep_bac/arc.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiI4BGZ8_MYCCN
AccessioniPrimary (citable) accession number: I4BGZ8
Entry historyi
Integrated into UniProtKB/TrEMBL: September 5, 2012
Last sequence update: September 5, 2012
Last modified: September 7, 2016
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.