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Protein

Superoxide dismutase [Cu-Zn]

Gene

Mycch_0510

Organism
Mycobacterium chubuense (strain NBB4)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

Cofactori

Protein has several cofactor binding sites:
  • Cu cationUniRule annotationNote: Binds 1 copper ion per subunit.UniRule annotation
  • Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. superoxide dismutase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Ligandi

CopperUniRule annotation, Metal-bindingUniRule annotation, ZincUniRule annotation

Enzyme and pathway databases

BioCyciMCHU710421:GLGL-510-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutase [Cu-Zn]UniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Mycch_0510Imported
OrganismiMycobacterium chubuense (strain NBB4)Imported
Taxonomic identifieri710421 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
ProteomesiUP000006057: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2929 PotentialImportedAdd
BLAST
Chaini30 – 266237 PotentialImportedPRO_5000912635Add
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the Cu-Zn superoxide dismutase family.UniRule annotation

Keywords - Domaini

SignalImported

Phylogenomic databases

KOiK04565.

Family and domain databases

Gene3Di2.60.40.200. 1 hit.
InterProiIPR018152. SOD_Cu/Zn_BS.
IPR001424. SOD_Cu_Zn_dom.
[Graphical view]
PfamiPF00080. Sod_Cu. 1 hit.
[Graphical view]
SUPFAMiSSF49329. SSF49329. 1 hit.
PROSITEiPS00332. SOD_CU_ZN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

I4BDH3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIRTVAAVTL FAAPALALTA CSPPGEVPAN SPGTPPPVWT GSPSPSSSMG
60 70 80 90 100
EQGAGEQGGV RQGGLAGVPQ EGGAQGRAGQ VGGNQSAPQQ AQSGGESLKA
110 120 130 140 150
DLKLADGTTV ASADIAFSGG YATVTVRTTA AGKLAPGFHG MHIHSVGKCE
160 170 180 190 200
PNSVAPTGGA PGNFNSAGGH LQVGGRSDHP ASGDLASLQV RGDGSAELVT
210 220 230 240 250
TTDAFTAQDL LNGAGTAIIV HEKADNFANI PADRYRQLDG APPPDQNTLA
260
TGDAGARVAC GVITRG
Length:266
Mass (Da):26,091
Last modified:September 5, 2012 - v1
Checksum:i3C62D34BB7DCCA5A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003053 Genomic DNA. Translation: AFM15330.1.
RefSeqiWP_014813822.1. NC_018027.1.
YP_006451009.1. NC_018027.1.

Genome annotation databases

EnsemblBacteriaiAFM15330; AFM15330; Mycch_0510.
GeneIDi13143645.
KEGGimcb:Mycch_0510.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003053 Genomic DNA. Translation: AFM15330.1.
RefSeqiWP_014813822.1. NC_018027.1.
YP_006451009.1. NC_018027.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFM15330; AFM15330; Mycch_0510.
GeneIDi13143645.
KEGGimcb:Mycch_0510.

Phylogenomic databases

KOiK04565.

Enzyme and pathway databases

BioCyciMCHU710421:GLGL-510-MONOMER.

Family and domain databases

Gene3Di2.60.40.200. 1 hit.
InterProiIPR018152. SOD_Cu/Zn_BS.
IPR001424. SOD_Cu_Zn_dom.
[Graphical view]
PfamiPF00080. Sod_Cu. 1 hit.
[Graphical view]
SUPFAMiSSF49329. SSF49329. 1 hit.
PROSITEiPS00332. SOD_CU_ZN_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of chromosome of Mycobacterium chubuense NBB4."
    US DOE Joint Genome Institute
    Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Mikhailova N., Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Mattes T.
    , Holmes A., Rutledge P., Paulsen I., Coleman N., Woyke T.
    Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NBB4Imported.

Entry informationi

Entry nameiI4BDH3_MYCCN
AccessioniPrimary (citable) accession number: I4BDH3
Entry historyi
Integrated into UniProtKB/TrEMBL: September 5, 2012
Last sequence update: September 5, 2012
Last modified: February 4, 2015
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.