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I4B751

- I4B751_TURPD

UniProt

I4B751 - I4B751_TURPD

Protein

Alanine racemase

Gene

Turpa_2466

Organism
Turneriella parva (strain ATCC BAA-1111 / DSM 21527 / NCTC 11395 / H) (Leptospira parva)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 16 (01 Oct 2014)
      Sequence version 1 (05 Sep 2012)
      Previous versions | rss
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    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotationSAAS annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei45 – 451Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei141 – 1411SubstrateUniRule annotation
    Active sitei277 – 2771Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei322 – 3221Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotation

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciTPAR869212:GLMM-2455-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Ordered Locus Names:Turpa_2466Imported
    OrganismiTurneriella parva (strain ATCC BAA-1111 / DSM 21527 / NCTC 11395 / H) (Leptospira parva)Imported
    Taxonomic identifieri869212 [NCBI]
    Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesLeptospiraceaeTurneriella
    ProteomesiUP000006048: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei45 – 451N6-(pyridoxal phosphate)lysineUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliI4B751.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    KOiK01775.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.
    PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    I4B751-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIDSTQTNHD SAPPVTLRIH ADALRHNLAR FRQLAPRSKI LLPVKANAYG    50
    CGLQTLFPVF QKNDVDVLGV ANCNEAVELR ALGWQKPVLN LGGFFRGNIQ 100
    SILDHQISAS ITDLWQVNEL NAAASGATVR VHLKLDLGMG RIGIRQNELP 150
    DLVSALKAAP NLQIDGMFTH FPHSGPEAAP FTLAQNENFV RISHELINEL 200
    QLERGSVTLH AANSYSAAFF SQTHHDMIRP GILFYGYYQS ESDRVQFNER 250
    FGFRPALELV ATPISVRTLR RGDGISYASL YHVTEEQETV AVLPLGYADG 300
    IPRALSNQIT FGRHPLRGRV TMDQIILGNA EGTSPIRLLG EGLPSLEYWG 350
    ELSHSFSYEL MSHLGNRIQR VLVD 374
    Length:374
    Mass (Da):41,463
    Last modified:September 5, 2012 - v1
    Checksum:i1A19486AAADDBBE9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002959 Genomic DNA. Translation: AFM13108.1.
    RefSeqiWP_014803614.1. NC_018020.1.
    YP_006440614.1. NC_018020.1.

    Genome annotation databases

    EnsemblBacteriaiAFM13108; AFM13108; Turpa_2466.
    GeneIDi13130972.
    KEGGitpx:Turpa_2466.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002959 Genomic DNA. Translation: AFM13108.1 .
    RefSeqi WP_014803614.1. NC_018020.1.
    YP_006440614.1. NC_018020.1.

    3D structure databases

    ProteinModelPortali I4B751.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AFM13108 ; AFM13108 ; Turpa_2466 .
    GeneIDi 13130972.
    KEGGi tpx:Turpa_2466.

    Phylogenomic databases

    KOi K01775.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci TPAR869212:GLMM-2455-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-1111 / DSM 21527 / NCTC 11395 / HImported.

    Entry informationi

    Entry nameiI4B751_TURPD
    AccessioniPrimary (citable) accession number: I4B751
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 5, 2012
    Last sequence update: September 5, 2012
    Last modified: October 1, 2014
    This is version 16 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3