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I4B5R2

- I4B5R2_TURPD

UniProt

I4B5R2 - I4B5R2_TURPD

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Protein
Submitted name: D-alanine--D-alanine ligase domain protein
Gene
Turpa_1972
Organism
Turneriella parva (strain ATCC BAA-1111 / DSM 21527 / NCTC 11395 / H) (Leptospira parva)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Cell wall formation By similarity.SAAS annotations

Catalytic activityi

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.SAAS annotations

Cofactori

Binds 2 magnesium or manganese ions per subunit By similarity.SAAS annotations

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. D-alanine-D-alanine ligase activity Source: InterPro
  3. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. peptidoglycan biosynthetic process Source: UniProtKB-UniPathway
  2. regulation of cell shape Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseSAAS annotationsImported

Keywords - Biological processi

Cell shape, Cell wall biogenesis/degradationSAAS annotations, Peptidoglycan synthesisSAAS annotations

Keywords - Ligandi

ATP-bindingSAAS annotations, MagnesiumSAAS annotations, ManganeseSAAS annotations, Metal-bindingSAAS annotations, Nucleotide-binding

Enzyme and pathway databases

BioCyciTPAR869212:GLMM-1958-MONOMER.
UniPathwayiUPA00219.

Names & Taxonomyi

Protein namesi
Submitted name:
D-alanine--D-alanine ligase domain proteinImported
Gene namesi
Ordered Locus Names:Turpa_1972Imported
OrganismiTurneriella parva (strain ATCC BAA-1111 / DSM 21527 / NCTC 11395 / H) (Leptospira parva)Imported
Taxonomic identifieri869212 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesLeptospiraceaeTurneriella
ProteomesiUP000006048: Chromosome

Subcellular locationi

Cytoplasm By similarity SAAS annotations

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmSAAS annotations

Family & Domainsi

Sequence similaritiesi

Contains ATP-grasp domain.SAAS annotations

Phylogenomic databases

KOiK01921.

Family and domain databases

Gene3Di3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
InterProiIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERiPTHR23132. PTHR23132. 1 hit.
PfamiPF07478. Dala_Dala_lig_C. 1 hit.
[Graphical view]
SUPFAMiSSF52440. SSF52440. 1 hit.
PROSITEiPS50975. ATP_GRASP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

I4B5R2-1 [UniParc]FASTAAdd to Basket

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MRVLVAFDFP TALPKNGDYR SLLHAEDWRP TRNVMEAIAR LGHEPILQGV    50
YDDILPLVFT IKRKKPDIVF NLLESFRQKR HYEGALAGLF DLLQVPYTGC 100
SAEALTICRN KSYTKLLLRH TKIKFPRSVV FPRGKTNRSI KDLKFPVIVK 150
PLGLEGSDGI SQASFVADEA ACIERVKTLH ETYEVDALAE EYIEGREIYA 200
GVLGLEKLTA LPLREMLFTN FPEDRPKFAT FHAKWNPEFR KKWGIKNTFA 250
KGIDEKTQAD IEQISKSAFR ALGLSGFARL DLRLTDKNEI FVLEVNPNPN 300
IANDDEIAYA SQRLGISYDQ LIQKLLDYGK RRRG 334
Length:334
Mass (Da):38,104
Last modified:September 5, 2012 - v1
Checksum:i355220509FE7DD80
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002959 Genomic DNA. Translation: AFM12619.1.
RefSeqiWP_014803126.1. NC_018020.1.
YP_006440125.1. NC_018020.1.

Genome annotation databases

EnsemblBacteriaiAFM12619; AFM12619; Turpa_1972.
GeneIDi13130475.
KEGGitpx:Turpa_1972.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002959 Genomic DNA. Translation: AFM12619.1 .
RefSeqi WP_014803126.1. NC_018020.1.
YP_006440125.1. NC_018020.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFM12619 ; AFM12619 ; Turpa_1972 .
GeneIDi 13130475.
KEGGi tpx:Turpa_1972.

Phylogenomic databases

KOi K01921.

Enzyme and pathway databases

UniPathwayi UPA00219 .
BioCyci TPAR869212:GLMM-1958-MONOMER.

Family and domain databases

Gene3Di 3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
InterProi IPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR016185. PreATP-grasp_dom.
[Graphical view ]
PANTHERi PTHR23132. PTHR23132. 1 hit.
Pfami PF07478. Dala_Dala_lig_C. 1 hit.
[Graphical view ]
SUPFAMi SSF52440. SSF52440. 1 hit.
PROSITEi PS50975. ATP_GRASP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-1111 / DSM 21527 / NCTC 11395 / H.

Entry informationi

Entry nameiI4B5R2_TURPD
AccessioniPrimary (citable) accession number: I4B5R2
Entry historyi
Integrated into UniProtKB/TrEMBL: September 5, 2012
Last sequence update: September 5, 2012
Last modified: September 3, 2014
This is version 11 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3