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I4B5R2

- I4B5R2_TURPD

UniProt

I4B5R2 - I4B5R2_TURPD

Protein
Submitted name:

D-alanine--D-alanine ligase domain protein

Gene

Turpa_1972

Organism
Turneriella parva (strain ATCC BAA-1111 / DSM 21527 / NCTC 11395 / H) (Leptospira parva)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 12 (01 Oct 2014)
      Sequence version 1 (05 Sep 2012)
      Previous versions | rss
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    Functioni

    Cell wall formation.SAAS annotation

    Catalytic activityi

    ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.SAAS annotation

    Cofactori

    Binds 2 magnesium or manganese ions per subunit.SAAS annotation

    Pathwayi

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. D-alanine-D-alanine ligase activity Source: InterPro
    3. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. peptidoglycan biosynthetic process Source: UniProtKB-UniPathway
    2. regulation of cell shape Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseSAAS annotationImported

    Keywords - Biological processi

    Cell shape, Cell wall biogenesis/degradationSAAS annotation, Peptidoglycan synthesisSAAS annotation

    Keywords - Ligandi

    ATP-bindingSAAS annotation, MagnesiumSAAS annotation, ManganeseSAAS annotation, Metal-bindingSAAS annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciTPAR869212:GLMM-1958-MONOMER.
    UniPathwayiUPA00219.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    D-alanine--D-alanine ligase domain proteinImported
    Gene namesi
    Ordered Locus Names:Turpa_1972Imported
    OrganismiTurneriella parva (strain ATCC BAA-1111 / DSM 21527 / NCTC 11395 / H) (Leptospira parva)Imported
    Taxonomic identifieri869212 [NCBI]
    Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesLeptospiraceaeTurneriella
    ProteomesiUP000006048: Chromosome

    Subcellular locationi

    Cytoplasm SAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmSAAS annotation

    Family & Domainsi

    Sequence similaritiesi

    Contains ATP-grasp domain.SAAS annotation

    Phylogenomic databases

    KOiK01921.

    Family and domain databases

    Gene3Di3.30.1490.20. 1 hit.
    3.30.470.20. 1 hit.
    InterProiIPR011761. ATP-grasp.
    IPR013815. ATP_grasp_subdomain_1.
    IPR013816. ATP_grasp_subdomain_2.
    IPR005905. D_ala_D_ala.
    IPR011095. Dala_Dala_lig_C.
    IPR016185. PreATP-grasp_dom.
    [Graphical view]
    PANTHERiPTHR23132. PTHR23132. 1 hit.
    PfamiPF07478. Dala_Dala_lig_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF52440. SSF52440. 1 hit.
    PROSITEiPS50975. ATP_GRASP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    I4B5R2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRVLVAFDFP TALPKNGDYR SLLHAEDWRP TRNVMEAIAR LGHEPILQGV    50
    YDDILPLVFT IKRKKPDIVF NLLESFRQKR HYEGALAGLF DLLQVPYTGC 100
    SAEALTICRN KSYTKLLLRH TKIKFPRSVV FPRGKTNRSI KDLKFPVIVK 150
    PLGLEGSDGI SQASFVADEA ACIERVKTLH ETYEVDALAE EYIEGREIYA 200
    GVLGLEKLTA LPLREMLFTN FPEDRPKFAT FHAKWNPEFR KKWGIKNTFA 250
    KGIDEKTQAD IEQISKSAFR ALGLSGFARL DLRLTDKNEI FVLEVNPNPN 300
    IANDDEIAYA SQRLGISYDQ LIQKLLDYGK RRRG 334
    Length:334
    Mass (Da):38,104
    Last modified:September 5, 2012 - v1
    Checksum:i355220509FE7DD80
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002959 Genomic DNA. Translation: AFM12619.1.
    RefSeqiWP_014803126.1. NC_018020.1.
    YP_006440125.1. NC_018020.1.

    Genome annotation databases

    EnsemblBacteriaiAFM12619; AFM12619; Turpa_1972.
    GeneIDi13130475.
    KEGGitpx:Turpa_1972.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002959 Genomic DNA. Translation: AFM12619.1 .
    RefSeqi WP_014803126.1. NC_018020.1.
    YP_006440125.1. NC_018020.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AFM12619 ; AFM12619 ; Turpa_1972 .
    GeneIDi 13130475.
    KEGGi tpx:Turpa_1972.

    Phylogenomic databases

    KOi K01921.

    Enzyme and pathway databases

    UniPathwayi UPA00219 .
    BioCyci TPAR869212:GLMM-1958-MONOMER.

    Family and domain databases

    Gene3Di 3.30.1490.20. 1 hit.
    3.30.470.20. 1 hit.
    InterProi IPR011761. ATP-grasp.
    IPR013815. ATP_grasp_subdomain_1.
    IPR013816. ATP_grasp_subdomain_2.
    IPR005905. D_ala_D_ala.
    IPR011095. Dala_Dala_lig_C.
    IPR016185. PreATP-grasp_dom.
    [Graphical view ]
    PANTHERi PTHR23132. PTHR23132. 1 hit.
    Pfami PF07478. Dala_Dala_lig_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52440. SSF52440. 1 hit.
    PROSITEi PS50975. ATP_GRASP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-1111 / DSM 21527 / NCTC 11395 / HImported.

    Entry informationi

    Entry nameiI4B5R2_TURPD
    AccessioniPrimary (citable) accession number: I4B5R2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 5, 2012
    Last sequence update: September 5, 2012
    Last modified: October 1, 2014
    This is version 12 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3