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Protein

D-alanine--D-alanine ligase

Gene

Turpa_1972

Organism
Turneriella parva (strain ATCC BAA-1111 / DSM 21527 / NCTC 11395 / H) (Leptospira parva)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cell wall formation.SAAS annotation

Catalytic activityi

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.SAAS annotation

Cofactori

Protein has several cofactor binding sites:
  • Mg2+SAAS annotation
  • Mn2+SAAS annotation

Pathwayi: peptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.SAAS annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigaseSAAS annotationImported
Biological processCell shape, Cell wall biogenesis/degradationSAAS annotation, Peptidoglycan synthesisSAAS annotation
LigandATP-bindingPROSITE-ProRule annotationSAAS annotation, MagnesiumSAAS annotation, ManganeseSAAS annotation, Metal-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciTPAR869212:G1H5V-1990-MONOMER
UniPathwayiUPA00219

Names & Taxonomyi

Protein namesi
Recommended name:
D-alanine--D-alanine ligaseSAAS annotation (EC:6.3.2.4SAAS annotation)
Gene namesi
Ordered Locus Names:Turpa_1972Imported
OrganismiTurneriella parva (strain ATCC BAA-1111 / DSM 21527 / NCTC 11395 / H) (Leptospira parva)Imported
Taxonomic identifieri869212 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesLeptospiralesLeptospiraceaeTurneriella
Proteomesi
  • UP000006048 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini115 – 327ATP-graspInterPro annotationAdd BLAST213

Sequence similaritiesi

Belongs to the D-alanine--D-alanine ligase family.SAAS annotation

Phylogenomic databases

KOiK01921
OMAiDINPNCD
OrthoDBiPOG091H1LUD

Family and domain databases

Gene3Di3.30.1490.201 hit
InterProiView protein in InterPro
IPR011761 ATP-grasp
IPR013815 ATP_grasp_subdomain_1
IPR011095 Dala_Dala_lig_C
IPR016185 PreATP-grasp_dom_sf
PfamiView protein in Pfam
PF07478 Dala_Dala_lig_C, 1 hit
SUPFAMiSSF52440 SSF52440, 1 hit
PROSITEiView protein in PROSITE
PS50975 ATP_GRASP, 1 hit

Sequencei

Sequence statusi: Complete.

I4B5R2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRVLVAFDFP TALPKNGDYR SLLHAEDWRP TRNVMEAIAR LGHEPILQGV
60 70 80 90 100
YDDILPLVFT IKRKKPDIVF NLLESFRQKR HYEGALAGLF DLLQVPYTGC
110 120 130 140 150
SAEALTICRN KSYTKLLLRH TKIKFPRSVV FPRGKTNRSI KDLKFPVIVK
160 170 180 190 200
PLGLEGSDGI SQASFVADEA ACIERVKTLH ETYEVDALAE EYIEGREIYA
210 220 230 240 250
GVLGLEKLTA LPLREMLFTN FPEDRPKFAT FHAKWNPEFR KKWGIKNTFA
260 270 280 290 300
KGIDEKTQAD IEQISKSAFR ALGLSGFARL DLRLTDKNEI FVLEVNPNPN
310 320 330
IANDDEIAYA SQRLGISYDQ LIQKLLDYGK RRRG
Length:334
Mass (Da):38,104
Last modified:September 5, 2012 - v1
Checksum:i355220509FE7DD80
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002959 Genomic DNA Translation: AFM12619.1
RefSeqiWP_014803126.1, NC_018020.1

Genome annotation databases

EnsemblBacteriaiAFM12619; AFM12619; Turpa_1972
KEGGitpx:Turpa_1972
PATRICifig|869212.3.peg.1976

Entry informationi

Entry nameiI4B5R2_TURPD
AccessioniPrimary (citable) accession number: I4B5R2
Entry historyiIntegrated into UniProtKB/TrEMBL: September 5, 2012
Last sequence update: September 5, 2012
Last modified: February 28, 2018
This is version 39 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported