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I4B5R2

- I4B5R2_TURPD

UniProt

I4B5R2 - I4B5R2_TURPD

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Protein
Submitted name:

D-alanine--D-alanine ligase domain protein

Gene

Turpa_1972

Organism
Turneriella parva (strain ATCC BAA-1111 / DSM 21527 / NCTC 11395 / H) (Leptospira parva)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

Cell wall formation.SAAS annotation

Catalytic activityi

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.SAAS annotation

Cofactori

Note: Binds 2 magnesium or manganese ions per subunit.SAAS annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. D-alanine-D-alanine ligase activity Source: InterPro
  3. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. cell wall organization Source: UniProtKB-KW
  2. peptidoglycan biosynthetic process Source: UniProtKB-UniPathway
  3. regulation of cell shape Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseSAAS annotationImported

Keywords - Biological processi

Cell shape, Cell wall biogenesis/degradationSAAS annotation, Peptidoglycan synthesisSAAS annotation

Keywords - Ligandi

ATP-bindingSAAS annotation, MagnesiumSAAS annotation, ManganeseSAAS annotation, Metal-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciTPAR869212:GLMM-1958-MONOMER.
UniPathwayiUPA00219.

Names & Taxonomyi

Protein namesi
Submitted name:
D-alanine--D-alanine ligase domain proteinImported
Gene namesi
Ordered Locus Names:Turpa_1972Imported
OrganismiTurneriella parva (strain ATCC BAA-1111 / DSM 21527 / NCTC 11395 / H) (Leptospira parva)Imported
Taxonomic identifieri869212 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesLeptospiraceaeTurneriella
ProteomesiUP000006048: Chromosome

Subcellular locationi

Cytoplasm SAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmSAAS annotation

Family & Domainsi

Sequence similaritiesi

Contains ATP-grasp domain.SAAS annotation

Phylogenomic databases

KOiK01921.

Family and domain databases

Gene3Di3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
InterProiIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERiPTHR23132. PTHR23132. 1 hit.
PfamiPF07478. Dala_Dala_lig_C. 1 hit.
[Graphical view]
SUPFAMiSSF52440. SSF52440. 1 hit.
PROSITEiPS50975. ATP_GRASP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

I4B5R2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRVLVAFDFP TALPKNGDYR SLLHAEDWRP TRNVMEAIAR LGHEPILQGV
60 70 80 90 100
YDDILPLVFT IKRKKPDIVF NLLESFRQKR HYEGALAGLF DLLQVPYTGC
110 120 130 140 150
SAEALTICRN KSYTKLLLRH TKIKFPRSVV FPRGKTNRSI KDLKFPVIVK
160 170 180 190 200
PLGLEGSDGI SQASFVADEA ACIERVKTLH ETYEVDALAE EYIEGREIYA
210 220 230 240 250
GVLGLEKLTA LPLREMLFTN FPEDRPKFAT FHAKWNPEFR KKWGIKNTFA
260 270 280 290 300
KGIDEKTQAD IEQISKSAFR ALGLSGFARL DLRLTDKNEI FVLEVNPNPN
310 320 330
IANDDEIAYA SQRLGISYDQ LIQKLLDYGK RRRG
Length:334
Mass (Da):38,104
Last modified:September 5, 2012 - v1
Checksum:i355220509FE7DD80
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002959 Genomic DNA. Translation: AFM12619.1.
RefSeqiWP_014803126.1. NC_018020.1.
YP_006440125.1. NC_018020.1.

Genome annotation databases

EnsemblBacteriaiAFM12619; AFM12619; Turpa_1972.
GeneIDi13130475.
KEGGitpx:Turpa_1972.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002959 Genomic DNA. Translation: AFM12619.1 .
RefSeqi WP_014803126.1. NC_018020.1.
YP_006440125.1. NC_018020.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFM12619 ; AFM12619 ; Turpa_1972 .
GeneIDi 13130475.
KEGGi tpx:Turpa_1972.

Phylogenomic databases

KOi K01921.

Enzyme and pathway databases

UniPathwayi UPA00219 .
BioCyci TPAR869212:GLMM-1958-MONOMER.

Family and domain databases

Gene3Di 3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
InterProi IPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR016185. PreATP-grasp_dom.
[Graphical view ]
PANTHERi PTHR23132. PTHR23132. 1 hit.
Pfami PF07478. Dala_Dala_lig_C. 1 hit.
[Graphical view ]
SUPFAMi SSF52440. SSF52440. 1 hit.
PROSITEi PS50975. ATP_GRASP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-1111 / DSM 21527 / NCTC 11395 / HImported.

Entry informationi

Entry nameiI4B5R2_TURPD
AccessioniPrimary (citable) accession number: I4B5R2
Entry historyi
Integrated into UniProtKB/TrEMBL: September 5, 2012
Last sequence update: September 5, 2012
Last modified: November 26, 2014
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3